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Published in: Breast Cancer Research and Treatment 1/2020

01-01-2020 | Breast Surgery | Rebuttal Letter

Risk-reducing mastectomy in BRCA mutation carriers: survival is one of the issues—author's reply

Authors: Bernadette Anna Maria Heemskerk-Gerritsen, Maartje Joanneke Hooning

Published in: Breast Cancer Research and Treatment | Issue 1/2020

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Excerpt

Words can do a lot of harm. One wrong headline in the lay press, shared on social media, can lead to a lot of misery. Misery for the women who underwent preventive breast surgery in the past and now could read in the news that this drastic operation may have been unnecessary. Misery for all dedicated clinicians who had to reassure these women that they had made the right decision, and also frustration for all investigators involved in the original paper who saw their message being framed so wrongly. …
Literature
1.
go back to reference Heemskerk-Gerritsen BAM, Jager A, Koppert LB, Obdeijn AI-M, Collée M, Meijers-Heijboer HEJ, Jenner DJ, Oldenburg HSA, van Engelen K, de Vries J, van Asperen CJ, Devilee P, Blok MJ, Kets CM, Ausems MGEM, Seynaeve C, Rookus MA, Hooning MJ (2019) Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 177(3):723–733CrossRef Heemskerk-Gerritsen BAM, Jager A, Koppert LB, Obdeijn AI-M, Collée M, Meijers-Heijboer HEJ, Jenner DJ, Oldenburg HSA, van Engelen K, de Vries J, van Asperen CJ, Devilee P, Blok MJ, Kets CM, Ausems MGEM, Seynaeve C, Rookus MA, Hooning MJ (2019) Survival after bilateral risk-reducing mastectomy in healthy BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 177(3):723–733CrossRef
2.
go back to reference Neven P, Punie K, Wildiers H, Willers N, Van Ongeval C, Van Buggenhout G, Legius E (2019) Risk-reducing mastectomy in BRCA carriers: survival is not the issue. Breast Cancer Res Treat Neven P, Punie K, Wildiers H, Willers N, Van Ongeval C, Van Buggenhout G, Legius E (2019) Risk-reducing mastectomy in BRCA carriers: survival is not the issue. Breast Cancer Res Treat
3.
go back to reference Evans DG, Howell SJ, Howell A (2019) Should unaffected female BRCA2 pathogenic variant carriers be told there is little or no advantage from risk reducing mastectomy? Fam Cancer 18(4):377–379CrossRef Evans DG, Howell SJ, Howell A (2019) Should unaffected female BRCA2 pathogenic variant carriers be told there is little or no advantage from risk reducing mastectomy? Fam Cancer 18(4):377–379CrossRef
Metadata
Title
Risk-reducing mastectomy in BRCA mutation carriers: survival is one of the issues—author's reply
Authors
Bernadette Anna Maria Heemskerk-Gerritsen
Maartje Joanneke Hooning
Publication date
01-01-2020
Publisher
Springer US
Published in
Breast Cancer Research and Treatment / Issue 1/2020
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-019-05487-3

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