Skip to main content
Top
Published in: Breast Cancer Research and Treatment 2/2009

01-07-2009 | Epidemiology

Complementary and alternative therapies among very long-term breast cancer survivors

Authors: C. L. Carpenter, P. A. Ganz, L. Bernstein

Published in: Breast Cancer Research and Treatment | Issue 2/2009

Login to get access

Abstract

Breast cancer patients may have different complementary and alternative medicine (CAM) usage rates and may turn to CAM for different reasons than healthy adults. CAM has mostly been studied in recently diagnosed women; no studies have included survivors 10 years post-diagnosis. We examined very long-term breast cancer survivors to determine whether CAM users had dissimilar patterns of association with survivorship factors. Interviews of 374 breast cancer case patients from a population-based case–control breast cancer study of young women from Los Angeles County, California, during the 1980s occurred at follow-up; 371 patients with complete information were included. CAM represented 28 herbal remedies. Quality-of-life originated from the Medical Outcomes Study Short Form 36 questionnaire (SF-36). Higher rates of CAM (59%) usage occurred compared to nationwide estimates. CAM users resembled non-users on follow-up age, exercise, original disease, treatment, smoking, body-mass index, alcohol, and fear of recurrence. CAM users had a higher prevalence of medical co-morbidities (P = 0.0005), and scored significantly lower on the SF-36 emotional well-being subscale than non-CAM users (P = 0.01). CAM users and non-users did not differ on the SF-36 physical sub-scale. Very long-term breast cancer survivors who use CAM may have poorer emotional functioning and more medical problems than non-users.
Literature
1.
go back to reference Barnes PM, Powell-Griner E, McFann K, Nahin RL (2004) Complementary and alternative medicine use among adults: United States, 2002. Adv Data from Vital Health Stat 343:1–20 Barnes PM, Powell-Griner E, McFann K, Nahin RL (2004) Complementary and alternative medicine use among adults: United States, 2002. Adv Data from Vital Health Stat 343:1–20
4.
go back to reference Boon HS, Olatunde F, Zick SM (2007) Trends in complementary and alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005. BMC Womens Health 7(4):1–7 Boon HS, Olatunde F, Zick SM (2007) Trends in complementary and alternative medicine use by breast cancer survivors: comparing survey data from 1998 and 2005. BMC Womens Health 7(4):1–7
6.
go back to reference Buettner C, Kroenke CH, Phillips RS, Davis RB, Eisenberg DM, Holmes MD (2006) Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses’ health study. Breast Cancer Res Treat 100:219–227. doi:10.1007/s10549-006-9239-3 PubMedCrossRef Buettner C, Kroenke CH, Phillips RS, Davis RB, Eisenberg DM, Holmes MD (2006) Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses’ health study. Breast Cancer Res Treat 100:219–227. doi:10.​1007/​s10549-006-9239-3 PubMedCrossRef
10.
go back to reference Patterson RE, Neuhouser ML, Hedderson MM, Schwartz SM, Standish LJ, Bowen DJ et al (2002) Types of alternative medicine used by patients with breast colon or prostate cancer: predictors, motives, and costs. J Altern Complement Med 8:477–485. doi:10.1089/107555302760253676 PubMedCrossRef Patterson RE, Neuhouser ML, Hedderson MM, Schwartz SM, Standish LJ, Bowen DJ et al (2002) Types of alternative medicine used by patients with breast colon or prostate cancer: predictors, motives, and costs. J Altern Complement Med 8:477–485. doi:10.​1089/​1075553027602536​76 PubMedCrossRef
11.
go back to reference Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR (2002) Quality-of-life in long-term, disease-free survivors of breast cancer: a follow-up study. J Natl Cancer Inst 94:39–49PubMed Ganz PA, Desmond KA, Leedham B, Rowland JH, Meyerowitz BE, Belin TR (2002) Quality-of-life in long-term, disease-free survivors of breast cancer: a follow-up study. J Natl Cancer Inst 94:39–49PubMed
14.
go back to reference Enger SM, Ross RK, Henderson BE, Bernstein L (1997) Breast feeding history, pregnancy experience and risk of breast cancer. Br J Cancer 76:118–123PubMed Enger SM, Ross RK, Henderson BE, Bernstein L (1997) Breast feeding history, pregnancy experience and risk of breast cancer. Br J Cancer 76:118–123PubMed
15.
go back to reference Mahue-Giangreco M, Ursin G, Sullivan-Halley J, Bernstein L (2003) Induced abortion, miscarriage and breast cancer risk of young women. Cancer Epidemiol Biomarkers Prev 12:209–214PubMed Mahue-Giangreco M, Ursin G, Sullivan-Halley J, Bernstein L (2003) Induced abortion, miscarriage and breast cancer risk of young women. Cancer Epidemiol Biomarkers Prev 12:209–214PubMed
19.
go back to reference Ware JE, Kosinski M (1994) SF-36 physical and mental health summary scales: a user’s manual. The Health Institute, Boston Ware JE, Kosinski M (1994) SF-36 physical and mental health summary scales: a user’s manual. The Health Institute, Boston
20.
go back to reference Ware JE, Kosinski M, Baylis MS, McHorney CA, Rogers WH, Raczek A (1995) Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the medical outcomes study. Med Care 33:AS264–AS279. doi:10.1097/00005650-199501001-00005 PubMedCrossRef Ware JE, Kosinski M, Baylis MS, McHorney CA, Rogers WH, Raczek A (1995) Comparison of methods for the scoring and statistical analysis of SF-36 health profile and summary measures: summary of results from the medical outcomes study. Med Care 33:AS264–AS279. doi:10.​1097/​00005650-199501001-00005 PubMedCrossRef
23.
go back to reference Ganz PA, Rowland JH, Desmond K, Meyerowitz BE, Wyatt GE (1998) Life after breast cancer: understanding women’s health-related quality-of-life and sexual functioning. J Clin Oncol 16:501–514PubMed Ganz PA, Rowland JH, Desmond K, Meyerowitz BE, Wyatt GE (1998) Life after breast cancer: understanding women’s health-related quality-of-life and sexual functioning. J Clin Oncol 16:501–514PubMed
27.
go back to reference Statistical Analysis System (2003) SAS Statistics Software, version 9.1.3 Statistical Analysis System (2003) SAS Statistics Software, version 9.1.3
28.
go back to reference Goldstein MS, Lee JH, Ballard-Barbash R, Brown ER (2008) The use and perceived benefit of complementary and alternative medicine among Californians with cancer. Psychooncology 17:19–25. doi:10.1002/pon.1193 PubMedCrossRef Goldstein MS, Lee JH, Ballard-Barbash R, Brown ER (2008) The use and perceived benefit of complementary and alternative medicine among Californians with cancer. Psychooncology 17:19–25. doi:10.​1002/​pon.​1193 PubMedCrossRef
29.
go back to reference Goldstein MS, Brown ER, Ballard-Barbash R, Morgenstern H, Bastani R, Lee J, Gatto N, Ambs A (2005) The use of complementary and alternative medicine among California adults with and without cancer. Evid Based Complement Alternat Med 2:557–565PubMedCrossRef Goldstein MS, Brown ER, Ballard-Barbash R, Morgenstern H, Bastani R, Lee J, Gatto N, Ambs A (2005) The use of complementary and alternative medicine among California adults with and without cancer. Evid Based Complement Alternat Med 2:557–565PubMedCrossRef
30.
go back to reference Barry D (1996) Differential recall bias and spurious associations in case–control studies. Stat Med 15:2603–2616. doi :10.1002/(SICI)1097-0258(19961215)15:23<2603::AID-SIM371>3.0.CO;2-GPubMedCrossRef Barry D (1996) Differential recall bias and spurious associations in case–control studies. Stat Med 15:2603–2616. doi :10.1002/(SICI)1097-0258(19961215)15:23<2603::AID-SIM371>3.0.CO;2-GPubMedCrossRef
Metadata
Title
Complementary and alternative therapies among very long-term breast cancer survivors
Authors
C. L. Carpenter
P. A. Ganz
L. Bernstein
Publication date
01-07-2009
Publisher
Springer US
Published in
Breast Cancer Research and Treatment / Issue 2/2009
Print ISSN: 0167-6806
Electronic ISSN: 1573-7217
DOI
https://doi.org/10.1007/s10549-008-0158-3

Other articles of this Issue 2/2009

Breast Cancer Research and Treatment 2/2009 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine