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AIDS and Behavior
Published in: AIDS and Behavior 5/2018

01-05-2018 | Original Paper

Psychological Factors Associated With Painful Versus Non-Painful HIV-Associated Sensory Neuropathy

Authors: Prinisha Pillay, Antonia L. Wadley, Catherine L. Cherry, Alan S. Karstaedt, Peter R. Kamerman

Published in: AIDS and Behavior | Issue 5/2018

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Abstract

HIV-associated sensory neuropathy (HIV-SN) is a common, and frequently painful complication of HIV, but factors that determine the presence of pain are unresolved. We investigated: (i) if psychological factors associated with painful (n = 125) versus non-painful HIV-SN (n = 72), and (ii) if pain and psychological factors affected quality of life (QoL). We assessed anxiety and depression using the Hopkins Symptoms Checklist-25. Pain catastrophizing and QoL were assessed using the Pain Catastrophizing Scale and Euroqol-5D, respectively. Presence of neuropathy was detected using the Brief Neuropathy Screening Tool, and pain was characterised using the Wisconsin Brief Pain Questionnaire. Overall, there was a high burden of pain, depression and anxiety in the cohort. None of the psychological variables associated with having painful HIV-SN. Greater depressive symptoms and presence of pain were independently associated with lower QoL. In those participants with painful HIV-SN, greater depressive symptom scores were associated with increased pain intensity. In conclusion, in a cohort with high background levels of psychological dysfunction, psychological factors do not predict the presence of pain, but both depression and presence of pain are associated with poor quality of life.
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Metadata
Title
Psychological Factors Associated With Painful Versus Non-Painful HIV-Associated Sensory Neuropathy
Authors
Prinisha Pillay
Antonia L. Wadley
Catherine L. Cherry
Alan S. Karstaedt
Peter R. Kamerman
Publication date
01-05-2018
Publisher
Springer US
Published in
AIDS and Behavior / Issue 5/2018
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-017-1856-9

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