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Published in: AIDS and Behavior 4/2015

01-04-2015 | Original Paper

Factors Enhancing Utilization of and Adherence to Prevention of Mother-to-Child Transmission (PMTCT) Service in an Urban Setting in Kenya

Authors: Lydia Karuta Murithi, Saba W. Masho, Allison A. Vanderbilt

Published in: AIDS and Behavior | Issue 4/2015

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Abstract

Despite expansive scale-up of prevention of mother-to-child transmission (PMTCT) of HIV services in Kenya over the last decade, Kenya remains one of the countries contributing to high numbers of children living with HIV globally and is among the 22 PMTCT global plan priority countries. Using structured and in-depth interviews this study examined enabling factors that enhance utilization of and adherence to PMTCT services in an urban setting in Kenya. HIV-positive birthmothers (N = 55) whose infants were HIV-negative at the time of the study completed a structured interview and a subset (n = 15) participated in in-depth interviews. The majority of the mothers (98 %) delivered at a health facility and 91 % exclusively breastfed. Further, 91 % attended clinic appointments regularly and 69.1 % strictly adhered to prescribed medication dosage and schedules. However, 18 % had not disclosed their HIV status to anybody, 27 % did not use condom during sex, 95 % did not participate in AIDS support groups and 53 % of their male partners were not involved in PMTCT. Four key themes facilitating PMTCT success emerged from the qualitative data: supportive counseling, striving for motherhood, assurance of confidentiality; and confirmation, affirmation and admiration. HIV/AIDS related stigma and gender imbalances create many missed opportunities for HIV-positive mothers to reach out for support from family and community, apply acquired knowledge and access more affordable care. To be successful, PMTCT programs should be aware of these factors and ensure that mothers are provided with culturally competent care.
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Literature
3.
go back to reference UNAIDS. Global report: UNAIDS report on the global AIDS epidemic: 2010. Geneva: Joint United Nations Programme on HIV/AIDS; 2010. UNAIDS. Global report: UNAIDS report on the global AIDS epidemic: 2010. Geneva: Joint United Nations Programme on HIV/AIDS; 2010.
5.
go back to reference Laher F, Cescon A, Lazarus E, Kaida A, Makongoza M, Hogg RS, et al. Conversations with mothers: exploring reasons for prevention of mother-to-child transmission (PMTCT) failures in the era of programmatic scale-up in Soweto, South Africa. AIDS Behav. 2012;16(1):91–8.CrossRefPubMed Laher F, Cescon A, Lazarus E, Kaida A, Makongoza M, Hogg RS, et al. Conversations with mothers: exploring reasons for prevention of mother-to-child transmission (PMTCT) failures in the era of programmatic scale-up in Soweto, South Africa. AIDS Behav. 2012;16(1):91–8.CrossRefPubMed
7.
go back to reference De Cock KM, Fowler MG, Mercier E, de Vincenzi I, Saba J, Hoff E, et al. Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice. JAMA J Am Med Assoc. 2000;283(9):1175–82.CrossRef De Cock KM, Fowler MG, Mercier E, de Vincenzi I, Saba J, Hoff E, et al. Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice. JAMA J Am Med Assoc. 2000;283(9):1175–82.CrossRef
8.
go back to reference McIntyre J, Lallemant M. The prevention of mother-to-child transmission of HIV: are we translating scientific success into programmatic failure? Curr Opin HIV AIDS. 2008;3(2):139–45.CrossRefPubMed McIntyre J, Lallemant M. The prevention of mother-to-child transmission of HIV: are we translating scientific success into programmatic failure? Curr Opin HIV AIDS. 2008;3(2):139–45.CrossRefPubMed
9.
go back to reference Both J, van Roosmalen J. The impact of prevention of mother to child transmission (PMTCT) programmes on maternal health care in resource-poor settings: looking beyond the PMTCT programme—a systematic review. BJOG Int J Obstet Gynaecol. 2010;117(12):1444–50.CrossRef Both J, van Roosmalen J. The impact of prevention of mother to child transmission (PMTCT) programmes on maternal health care in resource-poor settings: looking beyond the PMTCT programme—a systematic review. BJOG Int J Obstet Gynaecol. 2010;117(12):1444–50.CrossRef
13.
go back to reference Kagaayi J, Dreyfuss ML, Kigozi G, Chen MZ, Wabwire-Mangen F, Serwadda D, et al. Maternal self-medication and provision of nevirapine to newborns by women in Rakai, Uganda. J Acquir Immune Defic Syndr 1999. 2005;39(1):121–4.CrossRef Kagaayi J, Dreyfuss ML, Kigozi G, Chen MZ, Wabwire-Mangen F, Serwadda D, et al. Maternal self-medication and provision of nevirapine to newborns by women in Rakai, Uganda. J Acquir Immune Defic Syndr 1999. 2005;39(1):121–4.CrossRef
14.
go back to reference Songok EM, Fujiyama Y, Tukei PM, Vulule JM, Kiptoo MK, Adungo NO, et al. The use of short-course zidovudine to prevent perinatal transmission of human immunodeficiency virus in rural Kenya. Am J Trop Med Hyg. 2003;69(1):8–13.PubMed Songok EM, Fujiyama Y, Tukei PM, Vulule JM, Kiptoo MK, Adungo NO, et al. The use of short-course zidovudine to prevent perinatal transmission of human immunodeficiency virus in rural Kenya. Am J Trop Med Hyg. 2003;69(1):8–13.PubMed
15.
go back to reference Stringer EM, Ekouevi DK, Coetzee D, et al. Coverage of nevirapine-based services to prevent mother-to-child hiv transmission in 4 african countries. JAMA. 2010;304(3):293–302.CrossRefPubMed Stringer EM, Ekouevi DK, Coetzee D, et al. Coverage of nevirapine-based services to prevent mother-to-child hiv transmission in 4 african countries. JAMA. 2010;304(3):293–302.CrossRefPubMed
16.
go back to reference Ekouevi DK, Leroy V, Viho A, Bequet L, Horo A, Rouet F, et al. Acceptability and uptake of a package to prevent mother-to-child transmission using rapid HIV testing in Abidjan, Côte d’Ivoire. AIDS Lond Engl. 2004;18(4):697–700.CrossRef Ekouevi DK, Leroy V, Viho A, Bequet L, Horo A, Rouet F, et al. Acceptability and uptake of a package to prevent mother-to-child transmission using rapid HIV testing in Abidjan, Côte d’Ivoire. AIDS Lond Engl. 2004;18(4):697–700.CrossRef
17.
go back to reference Mandala J, Torpey K, Kasonde P, Kabaso M, Dirks R, Suzuki C, et al. Prevention of mother-to-child transmission of HIV in Zambia: implementing efficacious ARV regimens in primary health centers. BMC Public Health. 2009;9(1):314.CrossRefPubMedCentralPubMed Mandala J, Torpey K, Kasonde P, Kabaso M, Dirks R, Suzuki C, et al. Prevention of mother-to-child transmission of HIV in Zambia: implementing efficacious ARV regimens in primary health centers. BMC Public Health. 2009;9(1):314.CrossRefPubMedCentralPubMed
18.
go back to reference Manzi M, Zachariah R, Teck R, Buhendwa L, Kazima J, Bakali E, et al. High acceptability of voluntary counselling and HIV-testing but unacceptable loss to follow up in a prevention of mother-to-child HIV transmission programme in rural Malawi: scaling-up requires a different way of acting. Trop Med Int Health TM IH. 2005;10(12):1242–50.CrossRef Manzi M, Zachariah R, Teck R, Buhendwa L, Kazima J, Bakali E, et al. High acceptability of voluntary counselling and HIV-testing but unacceptable loss to follow up in a prevention of mother-to-child HIV transmission programme in rural Malawi: scaling-up requires a different way of acting. Trop Med Int Health TM IH. 2005;10(12):1242–50.CrossRef
19.
go back to reference Meda N, Leroy V, Viho I, Msellati P, Yaro S, Mandelbrot L, et al. Field acceptability and effectiveness of the routine utilization of zidovudine to reduce mother-to-child transmission of HIV-1 in West Africa. AIDS Lond Engl. 2002;16(17):2323–8.CrossRef Meda N, Leroy V, Viho I, Msellati P, Yaro S, Mandelbrot L, et al. Field acceptability and effectiveness of the routine utilization of zidovudine to reduce mother-to-child transmission of HIV-1 in West Africa. AIDS Lond Engl. 2002;16(17):2323–8.CrossRef
20.
go back to reference Perez F, Orne-Gliemann J, Mukotekwa T, Miller A, Glenshaw M, Mahomva A, et al. Prevention of mother to child transmission of HIV: evaluation of a pilot programme in a district hospital in rural Zimbabwe. BMJ. 2004;329(7475):1147–50.CrossRefPubMedCentralPubMed Perez F, Orne-Gliemann J, Mukotekwa T, Miller A, Glenshaw M, Mahomva A, et al. Prevention of mother to child transmission of HIV: evaluation of a pilot programme in a district hospital in rural Zimbabwe. BMJ. 2004;329(7475):1147–50.CrossRefPubMedCentralPubMed
21.
go back to reference Stringer JS, Sinkala M, Maclean CC, Levy J, Kankasa C, Degroot A, et al. Effectiveness of a city-wide program to prevent mother-to-child HIV transmission in Lusaka, Zambia. AIDS Lond Engl. 2005;19(12):1309–15.CrossRef Stringer JS, Sinkala M, Maclean CC, Levy J, Kankasa C, Degroot A, et al. Effectiveness of a city-wide program to prevent mother-to-child HIV transmission in Lusaka, Zambia. AIDS Lond Engl. 2005;19(12):1309–15.CrossRef
22.
go back to reference Arulogun OS, Adewole IF, Olayinka-Alli L, Adesina AO. Community gate keepers’ awareness and perception of prevention of mother-to-child transmission of HIV services in Ibadan, Nigeria. Afr J Reprod Health. 2007;11(1):67–75.CrossRefPubMed Arulogun OS, Adewole IF, Olayinka-Alli L, Adesina AO. Community gate keepers’ awareness and perception of prevention of mother-to-child transmission of HIV services in Ibadan, Nigeria. Afr J Reprod Health. 2007;11(1):67–75.CrossRefPubMed
23.
go back to reference Omowunmi A, Nkiru O, Yekeen R, Chinyere E, Muinat J, Segun A, et al. Knowledge, attitudes and perceptions of HIV/AIDS among traditional birth attendants and herbal practitioners in Lagos State, Nigeria. Afr J AIDS Res. 2005;3(2):191–6.CrossRef Omowunmi A, Nkiru O, Yekeen R, Chinyere E, Muinat J, Segun A, et al. Knowledge, attitudes and perceptions of HIV/AIDS among traditional birth attendants and herbal practitioners in Lagos State, Nigeria. Afr J AIDS Res. 2005;3(2):191–6.CrossRef
24.
go back to reference Mbonye AK, Hansen KS, Wamono F, Magnussen P. Barriers to prevention of mother-to-child transmission of HIV services in Uganda. J Biosoc Sci. 2010;42(2):271–83.CrossRefPubMed Mbonye AK, Hansen KS, Wamono F, Magnussen P. Barriers to prevention of mother-to-child transmission of HIV services in Uganda. J Biosoc Sci. 2010;42(2):271–83.CrossRefPubMed
25.
go back to reference Panditrao M, Darak S, Kulkarni V, Kulkarni S, Parchure R. Socio-demographic factors associated with loss to follow-up of HIV-infected women attending a private sector PMTCT program in Maharashtra, India. AIDS Care. 2011;23(5):593–600.CrossRefPubMed Panditrao M, Darak S, Kulkarni V, Kulkarni S, Parchure R. Socio-demographic factors associated with loss to follow-up of HIV-infected women attending a private sector PMTCT program in Maharashtra, India. AIDS Care. 2011;23(5):593–600.CrossRefPubMed
26.
go back to reference Mepham S, Zondi Z, Mbuyazi A, Mkhwanazi N, Newell ML. Challenges in PMTCT antiretroviral adherence in northern KwaZulu-Natal, South Africa. AIDS Care. 2011;23(6):741–7.CrossRefPubMed Mepham S, Zondi Z, Mbuyazi A, Mkhwanazi N, Newell ML. Challenges in PMTCT antiretroviral adherence in northern KwaZulu-Natal, South Africa. AIDS Care. 2011;23(6):741–7.CrossRefPubMed
27.
go back to reference Otieno PA, Kohler PK, Bosire RK, Brown ER, Macharia SW, John-Stewart GC. Determinants of failure to access care in mothers referred to HIV treatment programs in Nairobi, Kenya. AIDS Care. 2010;22(6):729–36.CrossRefPubMedCentralPubMed Otieno PA, Kohler PK, Bosire RK, Brown ER, Macharia SW, John-Stewart GC. Determinants of failure to access care in mothers referred to HIV treatment programs in Nairobi, Kenya. AIDS Care. 2010;22(6):729–36.CrossRefPubMedCentralPubMed
28.
go back to reference Peltzer K, Sikwane E, Majaja M. Factors associated with short-course antiretroviral prophylaxis (dual therapy) adherence for PMTCT in Nkangala district, South Africa. Acta Paediatr Oslo Nor 1992. 2011;100(9):1253–7. Peltzer K, Sikwane E, Majaja M. Factors associated with short-course antiretroviral prophylaxis (dual therapy) adherence for PMTCT in Nkangala district, South Africa. Acta Paediatr Oslo Nor 1992. 2011;100(9):1253–7.
29.
go back to reference Knafl KA. Patton, M.Q. (1990). Qualitative evaluation and research methods (2nd ed.). Newbury Park, CA: Sage, 532 pp., $28.00 (hardcover). Res Nurs Health. 1991;14 Suppl 1:73–4. Knafl KA. Patton, M.Q. (1990). Qualitative evaluation and research methods (2nd ed.). Newbury Park, CA: Sage, 532 pp., $28.00 (hardcover). Res Nurs Health. 1991;14 Suppl 1:73–4.
30.
go back to reference Krippendorff K. Content analysis: an introduction to its methodology […] […]. Thousand Oaks [u.a.: SAGE; 2004. Krippendorff K. Content analysis: an introduction to its methodology […] […]. Thousand Oaks [u.a.: SAGE; 2004.
31.
go back to reference De Cock KM, Mbori-Ngacha D, Marum E. Shadow on the continent: public health and HIV/AIDS in Africa in the 21st century. Lancet. 2002;360(9326):67–72.CrossRefPubMed De Cock KM, Mbori-Ngacha D, Marum E. Shadow on the continent: public health and HIV/AIDS in Africa in the 21st century. Lancet. 2002;360(9326):67–72.CrossRefPubMed
32.
go back to reference Gupta GR, ICRW. Approaches for empowering women in the HIV/Aids Pandemic–a Gender Perspective. Womens Int Netw News. 2001 Winter;27(1):14. Gupta GR, ICRW. Approaches for empowering women in the HIV/Aids Pandemic–a Gender Perspective. Womens Int Netw News. 2001 Winter;27(1):14.
33.
go back to reference Joy R, Druyts EF, Brandson EK, Lima VD, Rustad CA, Zhang W, et al. Impact of neighborhood-level socioeconomic status on HIV disease progression in a universal health care setting. J Acquir Immune Defic Syndr 1999. 2008;47(4):500–5.CrossRef Joy R, Druyts EF, Brandson EK, Lima VD, Rustad CA, Zhang W, et al. Impact of neighborhood-level socioeconomic status on HIV disease progression in a universal health care setting. J Acquir Immune Defic Syndr 1999. 2008;47(4):500–5.CrossRef
34.
go back to reference Kiwanuka SN, Ekirapa EK, Peterson S, Okui O, Rahman MH, Peters D, et al. Access to and utilisation of health services for the poor in Uganda: a systematic review of available evidence. Trans R Soc Trop Med Hyg. 2008;102(11):1067–74.CrossRefPubMed Kiwanuka SN, Ekirapa EK, Peterson S, Okui O, Rahman MH, Peters D, et al. Access to and utilisation of health services for the poor in Uganda: a systematic review of available evidence. Trans R Soc Trop Med Hyg. 2008;102(11):1067–74.CrossRefPubMed
35.
go back to reference Smith JA, Flowers P, Larkin M. Interpretative phenomenological analysis: theory, method and research. Los Angeles: SAGE; 2009. Smith JA, Flowers P, Larkin M. Interpretative phenomenological analysis: theory, method and research. Los Angeles: SAGE; 2009.
Metadata
Title
Factors Enhancing Utilization of and Adherence to Prevention of Mother-to-Child Transmission (PMTCT) Service in an Urban Setting in Kenya
Authors
Lydia Karuta Murithi
Saba W. Masho
Allison A. Vanderbilt
Publication date
01-04-2015
Publisher
Springer US
Published in
AIDS and Behavior / Issue 4/2015
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-014-0939-0

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