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Published in: AIDS and Behavior 3/2013

01-03-2013 | Original Paper

Prevalence and Predictors of Drug Use Among Adolescents with HIV Infection Acquired Perinatally or Later in Life

Authors: Latoya C. Conner, Jeffrey Wiener, Jennifer V. Lewis, Rhonda Phill, Ligia Peralta, Sulachni Chandwani, Linda J. Koenig

Published in: AIDS and Behavior | Issue 3/2013

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Abstract

We examined the prevalence and predictors of drug use among a diverse group of adolescents living with HIV infection acquired perinatally or through sexual risk behaviors (“behaviorally acquired”). Adolescents ages 13–21 (n = 166) who were receiving care at one of five pediatric/adolescent HIV clinics in three US cities (Baltimore MD, Washington DC, and New York NY) and were enrolled in a behavioral intervention were interviewed at baseline regarding lifetime drug use experiences and depression symptoms. A majority of study participants reported using alcohol (57.2%) and marijuana (51.2%); 48.8% reported tobacco/cigarette use. The mean age of onset of use for each type of drug was 14 years or younger. A larger proportion of participants with behaviorally acquired HIV than adolescents with perinatally acquired HIV reported lifetime use of alcohol (76.1 vs. 44.4%), marijuana (73.1 vs. 36.4%), tobacco (70.2 vs. 34.3%), and club drugs (22.4 vs. 3%) (all p < 0.001).
Literature
2.
go back to reference Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report, 2007. Vol. 19. [Table 1]. Atlanta: U.S. Department of Health and Human Services; 2009. Centers for Disease Control and Prevention. HIV/AIDS Surveillance Report, 2007. Vol. 19. [Table 1]. Atlanta: U.S. Department of Health and Human Services; 2009.
4.
go back to reference Whitmore SK, Hughes DP, Taylor AW, Koenig LJ. Estimated numbers and demographic characteristics of persons living with perinatally acquired HIV disease, 34 States, United States, 2007. 2010 July. Poster presented at the 18th international AIDS conference (Vienna, Austria). Whitmore SK, Hughes DP, Taylor AW, Koenig LJ. Estimated numbers and demographic characteristics of persons living with perinatally acquired HIV disease, 34 States, United States, 2007. 2010 July. Poster presented at the 18th international AIDS conference (Vienna, Austria).
5.
go back to reference Centers for Disease Control and Prevention. Youth risk behavior survey surveillance—United States, 2005. MMWR. 2005;55:14–22. Centers for Disease Control and Prevention. Youth risk behavior survey surveillance—United States, 2005. MMWR. 2005;55:14–22.
6.
go back to reference Johnston LD, O’Malley PM, Bachman JG. Monitoring the future national results in adolescent drug use: overview of key findings, 2002. Rockville, MD: National Institute on Drug Abuse; 2002. NIH publication No. 06-5882. Johnston LD, O’Malley PM, Bachman JG. Monitoring the future national results in adolescent drug use: overview of key findings, 2002. Rockville, MD: National Institute on Drug Abuse; 2002. NIH publication No. 06-5882.
8.
go back to reference Suris JC, Parera N. Sex, drugs and chronic illness: health behaviours among chronically ill youth. Eur J Public Health. 2005;15(5):484–8.PubMedCrossRef Suris JC, Parera N. Sex, drugs and chronic illness: health behaviours among chronically ill youth. Eur J Public Health. 2005;15(5):484–8.PubMedCrossRef
9.
go back to reference Rosenblum A, Magura S, Fong C. Substance use among young adolescents in HIV-affected families: resiliency, peer deviance, and family functioning. Subst Use Misuse. 2005;40:581–603.PubMedCrossRef Rosenblum A, Magura S, Fong C. Substance use among young adolescents in HIV-affected families: resiliency, peer deviance, and family functioning. Subst Use Misuse. 2005;40:581–603.PubMedCrossRef
10.
go back to reference Houck CD, Lescano CM, Brown LK, Tolou-Shams M, Thompson J, DiClemente R, et al. “Islands of risk”: subgroups of adolescents at risk for HIV. J Pediatr Psychol. 2006;31:619–29.PubMedCrossRef Houck CD, Lescano CM, Brown LK, Tolou-Shams M, Thompson J, DiClemente R, et al. “Islands of risk”: subgroups of adolescents at risk for HIV. J Pediatr Psychol. 2006;31:619–29.PubMedCrossRef
11.
go back to reference Bachanas PJ, Morris MK, Lewis-Gess JK, Sarett-Cuasay EJ, Flores AL, Sirl KS, et al. Psychological adjustment, substance use, HIV knowledge, and risky sexual behavior in at-risk minority females: developmental differences during adolescence. J Pediatr Psychol. 2002;27(4):373–84.PubMedCrossRef Bachanas PJ, Morris MK, Lewis-Gess JK, Sarett-Cuasay EJ, Flores AL, Sirl KS, et al. Psychological adjustment, substance use, HIV knowledge, and risky sexual behavior in at-risk minority females: developmental differences during adolescence. J Pediatr Psychol. 2002;27(4):373–84.PubMedCrossRef
12.
go back to reference Taney MR, Naar-King S, Murphy DA, Parsons JT, Janisse H. Multiple risk behaviors among youth living with Human Immunodeficiency Virus in five U.S. cities. J Adolesc Health. 2010;46:11–6.CrossRef Taney MR, Naar-King S, Murphy DA, Parsons JT, Janisse H. Multiple risk behaviors among youth living with Human Immunodeficiency Virus in five U.S. cities. J Adolesc Health. 2010;46:11–6.CrossRef
13.
go back to reference American Academy of Pediatrics Committee on Pediatric AIDS. Reducing the risk of HIV infection associated with illicit drug use. Pediatrics. 2006;117(2):566–71.CrossRef American Academy of Pediatrics Committee on Pediatric AIDS. Reducing the risk of HIV infection associated with illicit drug use. Pediatrics. 2006;117(2):566–71.CrossRef
15.
go back to reference Kennedy CA, Hill JM, Schleifer SJ. HIV/AIDS and substance use disorders. In: Frances RJ, Miller SI, Mack AH, editors. Clinical textbook of addictive disorders. 3rd ed. New York: The Guilford Press; 2005. p. 411–36. Kennedy CA, Hill JM, Schleifer SJ. HIV/AIDS and substance use disorders. In: Frances RJ, Miller SI, Mack AH, editors. Clinical textbook of addictive disorders. 3rd ed. New York: The Guilford Press; 2005. p. 411–36.
16.
go back to reference Nath A, Hauser KF, Wojna V, Booze RM, Maragos W, Prendergast M, et al. Molecular basis for interactions of HIV and drugs of abuse. J Acquir Immune Defic Syndr. 2002;31(2):62–9.CrossRef Nath A, Hauser KF, Wojna V, Booze RM, Maragos W, Prendergast M, et al. Molecular basis for interactions of HIV and drugs of abuse. J Acquir Immune Defic Syndr. 2002;31(2):62–9.CrossRef
17.
go back to reference Zweben JE, Denning P. The alcohol and drug wildcard: Substance use and psychiatric problems in people with HIV. San Francisco: UCSF AIDS Health Project; 1998. Zweben JE, Denning P. The alcohol and drug wildcard: Substance use and psychiatric problems in people with HIV. San Francisco: UCSF AIDS Health Project; 1998.
18.
go back to reference Chesney MA, Farmer P, Leandre F, Malow R, Starace F. Human immunodeficiency virus and acquired immunodeficiency syndrome. In: Sabate E, editor. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization; 2003. p. 95–106. Chesney MA, Farmer P, Leandre F, Malow R, Starace F. Human immunodeficiency virus and acquired immunodeficiency syndrome. In: Sabate E, editor. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization; 2003. p. 95–106.
19.
go back to reference Ammassari A, Trotta MP, Murri R, Castelli F, Narcisco P, Noto P, et al. Correlates and predictors of adherence to highly active retroviral therapy: overview of published literature. J Acquir Immune Defic Syndr. 2002;31(3):S123–7.PubMedCrossRef Ammassari A, Trotta MP, Murri R, Castelli F, Narcisco P, Noto P, et al. Correlates and predictors of adherence to highly active retroviral therapy: overview of published literature. J Acquir Immune Defic Syndr. 2002;31(3):S123–7.PubMedCrossRef
20.
go back to reference Comulada WS, Swendeman DT, Rotheram-Borus MJ, Mattes KM, Weiss RE. Use of HAART among young people living with HIV. Am J Health Behav. 2003;27:389–400.PubMedCrossRef Comulada WS, Swendeman DT, Rotheram-Borus MJ, Mattes KM, Weiss RE. Use of HAART among young people living with HIV. Am J Health Behav. 2003;27:389–400.PubMedCrossRef
21.
go back to reference Murphy DA, Belzer M, Durako SJ, Sarr M, Wilson CM, Muenz LR. Longitudinal antiretroviral adherence among adolescents infected with human immunodeficiency virus. Arch Pediatr Adolesc Med. 2005;159:764–70.PubMedCrossRef Murphy DA, Belzer M, Durako SJ, Sarr M, Wilson CM, Muenz LR. Longitudinal antiretroviral adherence among adolescents infected with human immunodeficiency virus. Arch Pediatr Adolesc Med. 2005;159:764–70.PubMedCrossRef
22.
go back to reference Naar-King S, Templin T, Wright K, Frey M, Parsons JT, Lam P. Psychosocial factors and medication adherence in HIV-positive youth. AIDS Patient Care STDs. 2006;20:44–7.PubMedCrossRef Naar-King S, Templin T, Wright K, Frey M, Parsons JT, Lam P. Psychosocial factors and medication adherence in HIV-positive youth. AIDS Patient Care STDs. 2006;20:44–7.PubMedCrossRef
23.
go back to reference Lyketsos CG, Treisman GJ. Mood disorders in HIV infection. Psychiatr Ann. 2001;31(1):45–9. Lyketsos CG, Treisman GJ. Mood disorders in HIV infection. Psychiatr Ann. 2001;31(1):45–9.
24.
go back to reference Brown G. The impact of HIV/AIDS on the African American woman and child: epidemiology, cultural and psychosocial issues and nursing management. Assoc Black Nurs Faculty J. 2001;12(3):60–2. Brown G. The impact of HIV/AIDS on the African American woman and child: epidemiology, cultural and psychosocial issues and nursing management. Assoc Black Nurs Faculty J. 2001;12(3):60–2.
25.
go back to reference Pence BW, Miller WC, Whetten K, Eron JJ, Gaynes BN. Prevalence of DSM-IV—defined mood, anxiety, and substance use disorders in an HIV clinic in the southeastern United States. J Acquir Immune Defic Synd. 2006;42(3):298–306.CrossRef Pence BW, Miller WC, Whetten K, Eron JJ, Gaynes BN. Prevalence of DSM-IV—defined mood, anxiety, and substance use disorders in an HIV clinic in the southeastern United States. J Acquir Immune Defic Synd. 2006;42(3):298–306.CrossRef
26.
go back to reference Colibazzi T, Hsu TT, Gilmer WS. Human immunodeficiency virus and depression in primary care: a clinical review. Prim Care Companion J Clin Psychiatr. 2006;8(4):201–11.CrossRef Colibazzi T, Hsu TT, Gilmer WS. Human immunodeficiency virus and depression in primary care: a clinical review. Prim Care Companion J Clin Psychiatr. 2006;8(4):201–11.CrossRef
27.
go back to reference Pao M, Lyon M, D’Angelo LJ, Schuman WB, Tipnis T, Mrazek DA. Psychiatric diagnoses in adolescents seropositive for the human immunodeficiency virus. Arch Pediatr Adol Med. 2000;154:240–4. Pao M, Lyon M, D’Angelo LJ, Schuman WB, Tipnis T, Mrazek DA. Psychiatric diagnoses in adolescents seropositive for the human immunodeficiency virus. Arch Pediatr Adol Med. 2000;154:240–4.
28.
go back to reference Marhefka SL, Lyon M, Koenig LJ, Orban L, Stein R, Lewis J, et al. Emotional and behavioral problems and mental health service utilization of youth living with HIV acquired perinatally or later in life. AIDS Care. 2009;21(11):1447–54.PubMedCrossRef Marhefka SL, Lyon M, Koenig LJ, Orban L, Stein R, Lewis J, et al. Emotional and behavioral problems and mental health service utilization of youth living with HIV acquired perinatally or later in life. AIDS Care. 2009;21(11):1447–54.PubMedCrossRef
29.
go back to reference Williams PL, Leister E, Chernoff M, Nachman S, Morse E, Di Poalo V, et al. Substance use and its association with psychiatric symptoms in perinatally HIV-infected and HIV-Affected adolescents. AIDS Behav. 2010;14:1072–82.PubMedCrossRef Williams PL, Leister E, Chernoff M, Nachman S, Morse E, Di Poalo V, et al. Substance use and its association with psychiatric symptoms in perinatally HIV-infected and HIV-Affected adolescents. AIDS Behav. 2010;14:1072–82.PubMedCrossRef
30.
go back to reference Mellins CA, Brackis-Cott E, Dolezal C, Abrams EJ. Psychiatric disorders in youth with perinatally acquired human immunodeficiency virus infection. Pediatr Inf Dis J. 2006;25(5):432–7.CrossRef Mellins CA, Brackis-Cott E, Dolezal C, Abrams EJ. Psychiatric disorders in youth with perinatally acquired human immunodeficiency virus infection. Pediatr Inf Dis J. 2006;25(5):432–7.CrossRef
31.
go back to reference Perkins DO, Leserman J, Stern RA, Baum SF, Liao D, Golden RN, et al. Somatic symptoms and HIV infection: relationship to depressive symptoms and indicators of HIV disease. Am J Psychiatr. 1995;152:1776–81.PubMed Perkins DO, Leserman J, Stern RA, Baum SF, Liao D, Golden RN, et al. Somatic symptoms and HIV infection: relationship to depressive symptoms and indicators of HIV disease. Am J Psychiatr. 1995;152:1776–81.PubMed
32.
go back to reference Coleman CL, Holzemer WL, Eller LS, Corless I, Reynolds N, Nokes KM, et al. Gender differences in use of prayer as a self-care strategy for managing symptoms in African Americans living with HIV/AIDS. J Assoc Nurses AIDS Care. 2006;17(4):16–23.PubMedCrossRef Coleman CL, Holzemer WL, Eller LS, Corless I, Reynolds N, Nokes KM, et al. Gender differences in use of prayer as a self-care strategy for managing symptoms in African Americans living with HIV/AIDS. J Assoc Nurses AIDS Care. 2006;17(4):16–23.PubMedCrossRef
33.
go back to reference Shacham E, Basta TB, Reece M. Symptoms of psychological distress among African Americans seeking HIV-related mental health care. AIDS Patient Care STDs. 2002;22(5):413–21.CrossRef Shacham E, Basta TB, Reece M. Symptoms of psychological distress among African Americans seeking HIV-related mental health care. AIDS Patient Care STDs. 2002;22(5):413–21.CrossRef
34.
go back to reference Abramowtiz S, Koenig LJ, Chandwani S, Orban L, Stein R, LaGrange R, et al. Characterizing social support: global and specific social support experiences of HIV-infected youth. AIDS Patient Care STDs. 2009;23(5):323–30.CrossRef Abramowtiz S, Koenig LJ, Chandwani S, Orban L, Stein R, LaGrange R, et al. Characterizing social support: global and specific social support experiences of HIV-infected youth. AIDS Patient Care STDs. 2009;23(5):323–30.CrossRef
35.
go back to reference Michaelis A. Living with HIV from birth into young adulthood: key issues facing a pioneering generation of HIV-positive youth in Baltimore. Workshop presented at the 136th annual meeting and expo of the American Public Health Association, Oct 2008, San Diego. Michaelis A. Living with HIV from birth into young adulthood: key issues facing a pioneering generation of HIV-positive youth in Baltimore. Workshop presented at the 136th annual meeting and expo of the American Public Health Association, Oct 2008, San Diego.
36.
go back to reference American Medical Association. Guidelines for adolescent prevention services. Chicago, IL: AMA; 1997. Product No. OP020997. American Medical Association. Guidelines for adolescent prevention services. Chicago, IL: AMA; 1997. Product No. OP020997.
37.
go back to reference Ziv A, Boulet JR, Slap GB. Utilization of physician offices by adolescents in the United States. Pediatrics. 1999;104(1):35–42.PubMedCrossRef Ziv A, Boulet JR, Slap GB. Utilization of physician offices by adolescents in the United States. Pediatrics. 1999;104(1):35–42.PubMedCrossRef
38.
go back to reference Rogers AS, Futterman DK, Moscicki AB, Wilson CM, Ellenberg J, Vermund SH. The REACH project of the adolescent medicine HIV/AIDS research network: design, methods, and selected characteristics of participants. J Adolesc Health. 1998;22:300–11.PubMedCrossRef Rogers AS, Futterman DK, Moscicki AB, Wilson CM, Ellenberg J, Vermund SH. The REACH project of the adolescent medicine HIV/AIDS research network: design, methods, and selected characteristics of participants. J Adolesc Health. 1998;22:300–11.PubMedCrossRef
39.
go back to reference Beck A, Ward C, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatr. 1961;4:561–71.PubMedCrossRef Beck A, Ward C, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatr. 1961;4:561–71.PubMedCrossRef
40.
go back to reference Roberts R, Lewisohn P, Seeley J. Screening for adolescent depression: a comparison of depression scales. J Am Acad Child Adolesc Psychiatr. 1991;30(1):58–66.CrossRef Roberts R, Lewisohn P, Seeley J. Screening for adolescent depression: a comparison of depression scales. J Am Acad Child Adolesc Psychiatr. 1991;30(1):58–66.CrossRef
41.
go back to reference Strober M, Green J, Carlson G. Utility of the beck depression inventory with psychiatrically hospitalized adolescents. J Clin Consult Psychol. 1981;49:482–3.CrossRef Strober M, Green J, Carlson G. Utility of the beck depression inventory with psychiatrically hospitalized adolescents. J Clin Consult Psychol. 1981;49:482–3.CrossRef
42.
go back to reference Teri L. Depression in adolescence: it’s relationship to assertion and various aspects of self-esteem. J Clin Child Psychol. 1982;11:101–6. Teri L. Depression in adolescence: it’s relationship to assertion and various aspects of self-esteem. J Clin Child Psychol. 1982;11:101–6.
43.
go back to reference Leadbeater B, Linares O. Depressive symptoms in black and Puerto Rican adolescent mothers in the first 3 years postpartum. Dev Psychopathol. 1992;4:451–68.CrossRef Leadbeater B, Linares O. Depressive symptoms in black and Puerto Rican adolescent mothers in the first 3 years postpartum. Dev Psychopathol. 1992;4:451–68.CrossRef
44.
go back to reference Barrera M, Garrison-Jones C. Properties of the Beck depression inventory as a screening instrument for adolescent depression. J Abnorm Child Psychol. 1988;16(3):263–73.PubMedCrossRef Barrera M, Garrison-Jones C. Properties of the Beck depression inventory as a screening instrument for adolescent depression. J Abnorm Child Psychol. 1988;16(3):263–73.PubMedCrossRef
45.
46.
go back to reference Anderson JR. Module 3: assessment issues and strategies in HOPE program training package 2006. Washington, DC: American Psychological Association; 2006:3–58.34. Anderson JR. Module 3: assessment issues and strategies in HOPE program training package 2006. Washington, DC: American Psychological Association; 2006:3–58.34.
47.
go back to reference Vega WA, Zimmerman RS, Warheit GJ, Apospori E, Gil AG. Risk factors for early adolescent drug use in four ethnic and racial groups. Am J Public Health. 1993;83(2):185–9.PubMedCrossRef Vega WA, Zimmerman RS, Warheit GJ, Apospori E, Gil AG. Risk factors for early adolescent drug use in four ethnic and racial groups. Am J Public Health. 1993;83(2):185–9.PubMedCrossRef
48.
go back to reference Crepaz N, Marks G. Are negative affective states associated with HIV sexual risk behaviors? A meta-analytic review. Health Psychol. 2001;20:291–9.PubMedCrossRef Crepaz N, Marks G. Are negative affective states associated with HIV sexual risk behaviors? A meta-analytic review. Health Psychol. 2001;20:291–9.PubMedCrossRef
49.
go back to reference O’Leary A, Broadwell SD, Yao P, Hasin D. Major depression, alcohol and drug use disorders do not appear to account for the sexually transmitted disease and HIV epidemics in the Southern United States. Sex Transm Dis. 2006;33(7):S70–7.PubMed O’Leary A, Broadwell SD, Yao P, Hasin D. Major depression, alcohol and drug use disorders do not appear to account for the sexually transmitted disease and HIV epidemics in the Southern United States. Sex Transm Dis. 2006;33(7):S70–7.PubMed
50.
go back to reference Murphy DA, Wilson CM, Durako SJ, Muenz LR, Belzer M. Antiretroviral medication adherence among the REACH HIV-infected adolescent cohort in the USA. AIDS Care. 2001;13(1):27–40.PubMedCrossRef Murphy DA, Wilson CM, Durako SJ, Muenz LR, Belzer M. Antiretroviral medication adherence among the REACH HIV-infected adolescent cohort in the USA. AIDS Care. 2001;13(1):27–40.PubMedCrossRef
51.
52.
go back to reference Marlatt G. Harm reduction: pragmatic strategies for managing high-risk behaviors. New York: The Guilford Press; 1998. Marlatt G. Harm reduction: pragmatic strategies for managing high-risk behaviors. New York: The Guilford Press; 1998.
53.
go back to reference Miller WR, Rollnick S. Motivational interviewing: preparing people for change. New York: The Guilford Press; 2002. Miller WR, Rollnick S. Motivational interviewing: preparing people for change. New York: The Guilford Press; 2002.
54.
go back to reference Prochaska JO, DiClimente CC. Stages of change in the modification of problem behaviors. Sage: Newbury Park; 1992. Prochaska JO, DiClimente CC. Stages of change in the modification of problem behaviors. Sage: Newbury Park; 1992.
Metadata
Title
Prevalence and Predictors of Drug Use Among Adolescents with HIV Infection Acquired Perinatally or Later in Life
Authors
Latoya C. Conner
Jeffrey Wiener
Jennifer V. Lewis
Rhonda Phill
Ligia Peralta
Sulachni Chandwani
Linda J. Koenig
Publication date
01-03-2013
Publisher
Springer US
Published in
AIDS and Behavior / Issue 3/2013
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-011-9950-x

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