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Keynote webinar | Spotlight on medication adherence

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AIDS and Behavior
Published in: AIDS and Behavior 5/2011

01-07-2011 | Original Paper

A Preliminary Randomized Controlled Trial of a Nurse-Delivered Medication Adherence Intervention Among HIV-Positive Outpatients Initiating Antiretroviral Therapy in Beijing, China

Authors: Jane M. Simoni, Wei-Ti Chen, David Huh, Karen I. Fredriksen-Goldsen, Cynthia Pearson, Hongxin Zhao, Cheng-Shi Shiu, Xin Wang, Fujie Zhang

Published in: AIDS and Behavior | Issue 5/2011

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Abstract

We evaluated a nurse-delivered adherence intervention in a preliminary randomized controlled trial among 70 HIV-positive outpatients initiating antiretroviral therapy (ART) in Beijing, China. In both arms, participants received a 30-min educational session, a pillbox, and a referral to a peer support group. In the enhanced arm, participants could choose an electronic reminder device, three sessions of counseling either alone or with a treatment adherence partner, or both reminder and counseling. Survey assessments and blood draws occurred at baseline, post-intervention (13 weeks), and follow-up (25 weeks). Primary outcomes were 7-day and 30-day adherence assessed by self-report and electronic drug monitoring (EDM), and secondary outcomes were HIV-1 RNA viral load and CD4 count. The intervention was feasible and well received. It led to some improvement in self-reported and EDM-assessed adherence but not the biological outcomes. Providing counseling and facilitating the use of electronic reminders to patients initiating ART merits further investigation as a culturally viable means of promoting adherence in China.
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Metadata
Title
A Preliminary Randomized Controlled Trial of a Nurse-Delivered Medication Adherence Intervention Among HIV-Positive Outpatients Initiating Antiretroviral Therapy in Beijing, China
Authors
Jane M. Simoni
Wei-Ti Chen
David Huh
Karen I. Fredriksen-Goldsen
Cynthia Pearson
Hongxin Zhao
Cheng-Shi Shiu
Xin Wang
Fujie Zhang
Publication date
01-07-2011
Publisher
Springer US
Published in
AIDS and Behavior / Issue 5/2011
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-010-9828-3

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Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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