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Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
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AIDS and Behavior
Published in: AIDS and Behavior 1/2009

01-02-2009 | Original Research

Adherence to Antiretroviral Medication Regimens: A Test of a Psychosocial Model

Authors: Colleen DiIorio, Frances McCarty, Lara DePadilla, Ken Resnicow, Marcia McDonnell Holstad, Katherine Yeager, Sanjay M. Sharma, Donald E. Morisky, Brita Lundberg

Published in: AIDS and Behavior | Issue 1/2009

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Abstract

Objective The primary aim of this study was to test a psychosocial model of medication adherence among people taking antiretroviral medications. This model was based primarily on social cognitive theory and included personal (self-efficacy, outcome expectancy, stigma, depression, and spirituality), social (social support, difficult life circumstances), and provider (patient satisfaction and decision-making) variables. Design The data for this analysis were obtained from the parent study, which was a randomized controlled trial (Get Busy Living) designed to evaluate an intervention to foster medication adherence. Factor analysis was used to develop the constructs for the model, and structural equation modeling was used to test the model. Only baseline data were used in this cross sectional analysis. Methods Participants were recruited from a HIV/AIDS clinic in Atlanta, GA. Prior to group assignment, participants were asked to complete a questionnaire that included assessment of the study variables. Results A total of 236 participants were included in the analysis. The mean age of the participants was 41 years; the majority were male, and most were African-American. In the final model, self-efficacy and depression demonstrated direct associations with adherence; whereas stigma, patient satisfaction, and social support were indirectly related to adherence through their association with either self-efficacy or depression. Conclusion These findings provide evidence to reinforce the belief that medication-taking behaviors are affected by a complex set of interactions among psychosocial variables and provide direction for adherence interventions.
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Metadata
Title
Adherence to Antiretroviral Medication Regimens: A Test of a Psychosocial Model
Authors
Colleen DiIorio
Frances McCarty
Lara DePadilla
Ken Resnicow
Marcia McDonnell Holstad
Katherine Yeager
Sanjay M. Sharma
Donald E. Morisky
Brita Lundberg
Publication date
01-02-2009
Publisher
Springer US
Published in
AIDS and Behavior / Issue 1/2009
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-007-9318-4

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