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Keynote webinar | Spotlight on medication adherence

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AIDS and Behavior
Published in: AIDS and Behavior 3/2006

01-05-2006

The Differential Impact of PTSD and Depression on HIV Disease Markers and Adherence to HAART in People Living with HIV

Authors: Jessica M. Boarts, Eve M. Sledjeski, Laura M. Bogart, Douglas L. Delahanty

Published in: AIDS and Behavior | Issue 3/2006

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Abstract

Despite high rates of comorbidity, research has typically focused on the independent impact of posttraumatic stress disorder (PTSD) and depression symptoms in people living with HIV (PLWH). The present study examined the independent and comorbid influence of PTSD and depression symptoms on medication adherence, CD4 cell counts, and viral load, over the course of 3 months in 57 PLWH (82% men, 54% Caucasian, 44% African American) recruited from a clinic or social service agency. Both PTSD and depressive symptoms predicted lower subsequent adherence. However, only depressive symptoms predicted lower CD4 counts and presence of a detectable viral load. Participants reporting symptoms consistent with diagnostic levels of comorbid PTSD and depression were less likely to adhere to HAART and were more likely to have a detectable viral load. These results highlight the influences of PTSD and depression on adherence and HIV disease markers, and underscore the importance of examining comorbid symptomatology in PLWH.
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Metadata
Title
The Differential Impact of PTSD and Depression on HIV Disease Markers and Adherence to HAART in People Living with HIV
Authors
Jessica M. Boarts
Eve M. Sledjeski
Laura M. Bogart
Douglas L. Delahanty
Publication date
01-05-2006
Publisher
Springer US
Published in
AIDS and Behavior / Issue 3/2006
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-006-9069-7

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