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Magnetic Resonance Materials in Physics, Biology and Medicine

Published in:

01-10-2014 | Research Article

Automated segmentation and volumetric analysis of renal cortex, medulla, and pelvis based on non-contrast-enhanced T1- and T2-weighted MR images

Authors: Susanne Will, Petros Martirosian, Christian Würslin, Fritz Schick

Published in: Magnetic Resonance Materials in Physics, Biology and Medicine | Issue 5/2014

Abstract

Object

The aim of our study was to enable automatic volumetry of the entire kidneys as well as their internal structures (cortex, medulla, and pelvis) from native magnetic resonance imaging (MRI) data sets.

Materials and methods

Segmentation of the entire kidneys and differentiation of their internal structures were performed in 12 healthy volunteers based on non-contrast-enhanced T1- and T2-weighted MR images. Two data sets (each acquired in one breath-hold) were co-registered using a rigid registration algorithm compensating for possible breathing-related displacements. An automatic algorithm based on thresholding and shape detection segmented the kidneys into their compartments and was compared to a manual labeling procedure.

Results

The resulting kidney volumes of the automated segmentation correlated well with those created manually (R ² = 0.96). Average volume errors were determined to be 4.97 ± 4.08 % (entire kidney parenchyma), 7.03 ± 5.56 % (cortex), 12.33 ± 7.35 % (medulla), and 17.57 ± 14.47 % (pelvis). The variation of the kidney volume resulting from the automatic algorithm was found to be 4.76 % based on the measuring of one volunteer with three independent examinations.

Conclusion

The results demonstrate the feasibility of an accurate and repeatable automatic segmentation of the kidneys and their internal structures from non-contrast-enhanced magnetic resonance images.

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Title: Automated segmentation and volumetric analysis of renal cortex, medulla, and pelvis based on non-contrast-enhanced T1- and T2-weighted MR images
Authors: Susanne Will
Petros Martirosian
Christian Würslin
Fritz Schick
Publication date: 01-10-2014
Publisher: Springer Berlin Heidelberg
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine / Issue 5/2014
Print ISSN: 0968-5243
Electronic ISSN: 1352-8661
DOI: https://doi.org/10.1007/s10334-014-0429-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Automated segmentation and volumetric analysis of renal cortex, medulla, and pelvis based on non-contrast-enhanced T1- and T2-weighted MR images

Abstract

Object

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Object

Materials and methods

Results

Conclusion

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