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Published in: Modern Rheumatology 1/2009

01-02-2009 | Case Report

Masked early symptoms of pneumonia in patients with rheumatoid arthritis during tocilizumab treatment: a report of two cases

Authors: Hiroshi Fujiwara, Norihiro Nishimoto, Yoshimasa Hamano, Nobuyuki Asanuma, Shunji Miki, Soji Kasayama, Masaki Suemura

Published in: Modern Rheumatology | Issue 1/2009

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Abstract

Although reports of serious infections in clinical trials for rheumatoid arthritis (RA) with tocilizumab, anti-interleukin6 (IL-6) receptor antibody, have been relatively few, there is still some concern about infections. We report here two cases of patients who developed severe pneumonia during tocilizumab treatment for RA. Both patients initially presented with only minimal clinical symptoms and modest elevations in serum C-reactive protein. Tocilizumab might suppress the early inflammatory symptoms of pneumonia.
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Metadata
Title
Masked early symptoms of pneumonia in patients with rheumatoid arthritis during tocilizumab treatment: a report of two cases
Authors
Hiroshi Fujiwara
Norihiro Nishimoto
Yoshimasa Hamano
Nobuyuki Asanuma
Shunji Miki
Soji Kasayama
Masaki Suemura
Publication date
01-02-2009
Publisher
Springer Japan
Published in
Modern Rheumatology / Issue 1/2009
Print ISSN: 1439-7595
Electronic ISSN: 1439-7609
DOI
https://doi.org/10.1007/s10165-008-0111-7

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