Skip to main content
Top
Published in: Gastric Cancer 3/2012

01-07-2012 | Original article

The flow angle beneath the gastrojejunostomy predicts delayed gastric emptying in Roux-en-Y reconstruction after distal gastrectomy

Authors: Toshihiko Masui, Toyonari Kubora, Yasutaka Nakanishi, Keiko Aoki, Shinichi Sugimoto, Michio Takamura, Hiroshi Takeda, Koji Hashimoto, Atsuo Tokuka

Published in: Gastric Cancer | Issue 3/2012

Login to get access

Abstract

Background

Delayed gastric emptying without mechanical obstruction after Roux-en-Y reconstruction has been defined as Roux stasis syndrome. It occurs in 10–30% of patients after such reconstruction. So far, the cause of this stasis has not been completely identified. This study aimed to reduce Roux stasis using surgical techniques.

Methods

From November 2007 to October 2010, we performed 101 distal gastrectomies with Roux-en-Y reconstruction. All the gastrojejunostomies were performed with end-to-end anastomoses. Roux stasis was analyzed with respect to tumor location, extent of the dissection, tumor progression, operation time, antecolic/retrocolic reconstruction, and the shape of the gastrojejunostomy. The shape of the gastrojejunostomy was evaluated by contrast gastroradiography 4 days after the operation.

Results

Roux stasis syndrome was observed in 17 of the 101 patients. There was no relationship between the extent of the dissection, tumor progression, or operation time and the occurrence of Roux stasis. There was no difference in the incidence of Roux stasis between antecolic and retrocolic reconstructions. However, the group that displayed a straight anastomotic shape on contrast radiography demonstrated an apparently lower incidence of Roux stasis (p = 0.0003). In addition, Roux-en-Y reconstruction following gastric cancer was more frequently followed by Roux stasis in the antrum than in the midstomach (p = 0.0036). Cases of Roux stasis occurred 11.8 days after surgery on average and resolved within 2 weeks on average.

Conclusions

Our findings demonstrate the substantial benefits of a straight anastomosis of the gastrojejunostomy for the prevention of Roux stasis syndrome.
Literature
1.
go back to reference Fukuhara K, Osugi H, Takada N, Takemura M, Higashino M, Kinoshita H. Reconstructive procedure after distal gastrectomy for gastric cancer that best prevents duodenogastroesophageal reflux. World J Surg. 2002;26(12):1452–7.PubMedCrossRef Fukuhara K, Osugi H, Takada N, Takemura M, Higashino M, Kinoshita H. Reconstructive procedure after distal gastrectomy for gastric cancer that best prevents duodenogastroesophageal reflux. World J Surg. 2002;26(12):1452–7.PubMedCrossRef
2.
go back to reference Fukuhara K, Osugi H, Takada N, Takemura M, Ohmoto Y, Kinoshita H. Quantitative determinations of duodenogastric reflux, prevalence of Helicobacter pylori infection, and concentrations of interleukin-8. World J Surg. 2003;27(5):567–70.PubMedCrossRef Fukuhara K, Osugi H, Takada N, Takemura M, Ohmoto Y, Kinoshita H. Quantitative determinations of duodenogastric reflux, prevalence of Helicobacter pylori infection, and concentrations of interleukin-8. World J Surg. 2003;27(5):567–70.PubMedCrossRef
3.
go back to reference Langhans P, Schonleben K, Bunte H. The routine use of Roux-en-Y anastomosis in gastric surgery. Scand J Gastroenterol Suppl. 1981;67:247–9.PubMed Langhans P, Schonleben K, Bunte H. The routine use of Roux-en-Y anastomosis in gastric surgery. Scand J Gastroenterol Suppl. 1981;67:247–9.PubMed
4.
go back to reference Hoya Y, Mitsumori N, Yanaga K. The advantages and disadvantages of a Roux-en-Y reconstruction after a distal gastrectomy for gastric cancer. Surg Today. 2009;39(8):647–51.PubMedCrossRef Hoya Y, Mitsumori N, Yanaga K. The advantages and disadvantages of a Roux-en-Y reconstruction after a distal gastrectomy for gastric cancer. Surg Today. 2009;39(8):647–51.PubMedCrossRef
5.
go back to reference Mathias JR, Fernandez A, Sninsky CA, Clench MH, Davis RH. Nausea, vomiting, and abdominal pain after Roux-en-Y anastomosis: motility of the jejunal limb. Gastroenterology. 1985;88(1 Pt 1):101–7.PubMed Mathias JR, Fernandez A, Sninsky CA, Clench MH, Davis RH. Nausea, vomiting, and abdominal pain after Roux-en-Y anastomosis: motility of the jejunal limb. Gastroenterology. 1985;88(1 Pt 1):101–7.PubMed
6.
go back to reference Miedema BW, Kelly KA, Camilleri M, et al. Human gastric and jejunal transit and motility after Roux gastrojejunostomy. Gastroenterology. 1992;103(4):1133–43.PubMed Miedema BW, Kelly KA, Camilleri M, et al. Human gastric and jejunal transit and motility after Roux gastrojejunostomy. Gastroenterology. 1992;103(4):1133–43.PubMed
7.
go back to reference Bar-Natan M, Larson GM, Stephens G, Massey T. Delayed gastric emptying after gastric surgery. Am J Surg. 1996;172(1):24–8.PubMedCrossRef Bar-Natan M, Larson GM, Stephens G, Massey T. Delayed gastric emptying after gastric surgery. Am J Surg. 1996;172(1):24–8.PubMedCrossRef
8.
go back to reference Britton JP, Johnston D, Ward DC, Axon AT, Barker MC. Gastric emptying and clinical outcome after Roux-en-Y diversion. Br J Surg. 1987;74(10):900–4.PubMedCrossRef Britton JP, Johnston D, Ward DC, Axon AT, Barker MC. Gastric emptying and clinical outcome after Roux-en-Y diversion. Br J Surg. 1987;74(10):900–4.PubMedCrossRef
9.
go back to reference Gustavsson S, Ilstrup DM, Morrison P, Kelly KA. Roux-Y stasis syndrome after gastrectomy. Am J Surg. 1988;155(3):490–4.PubMedCrossRef Gustavsson S, Ilstrup DM, Morrison P, Kelly KA. Roux-Y stasis syndrome after gastrectomy. Am J Surg. 1988;155(3):490–4.PubMedCrossRef
10.
go back to reference Herrington JL Jr, Scott HW Jr, Sawyers JL. Experience with vagotomy–antrectomy and Roux-en-Y gastrojejunostomy in surgical treatment of duodenal, gastric, and stomal ulcers. Ann Surg. 1984;199(5):590–7.PubMedCrossRef Herrington JL Jr, Scott HW Jr, Sawyers JL. Experience with vagotomy–antrectomy and Roux-en-Y gastrojejunostomy in surgical treatment of duodenal, gastric, and stomal ulcers. Ann Surg. 1984;199(5):590–7.PubMedCrossRef
11.
go back to reference Hermon-Taylor J, Code CF. Localization of the duodenal pacemaker and its role in the organization of duodenal myoelectric activity. Gut. 1971;12(1):40–7.PubMedCrossRef Hermon-Taylor J, Code CF. Localization of the duodenal pacemaker and its role in the organization of duodenal myoelectric activity. Gut. 1971;12(1):40–7.PubMedCrossRef
12.
go back to reference van der Mijle HC, Kleibeuker JH, Limburg AJ, Bleichrodt RP, Beekhuis H, van Schilfgaarde R. Manometric and scintigraphic studies of the relation between motility disturbances in the Roux limb and the Roux-en-Y syndrome. Am J Surg. 1993;166(1):11–7.PubMedCrossRef van der Mijle HC, Kleibeuker JH, Limburg AJ, Bleichrodt RP, Beekhuis H, van Schilfgaarde R. Manometric and scintigraphic studies of the relation between motility disturbances in the Roux limb and the Roux-en-Y syndrome. Am J Surg. 1993;166(1):11–7.PubMedCrossRef
13.
go back to reference Mathias JR, Khanna R, Nealon WH, Browne RM, Reeves-Darby VG, Clench MH. Roux-limb motility after total gastrectomy and Roux-en-Y anastomosis in patients with Zollinger–Ellison syndrome. Dig Dis Sci. 1992;37(4):545–50.PubMedCrossRef Mathias JR, Khanna R, Nealon WH, Browne RM, Reeves-Darby VG, Clench MH. Roux-limb motility after total gastrectomy and Roux-en-Y anastomosis in patients with Zollinger–Ellison syndrome. Dig Dis Sci. 1992;37(4):545–50.PubMedCrossRef
14.
go back to reference Miedema BW, Kelly KA. The Roux stasis syndrome. Treatment by pacing and prevention by use of an ‘uncut’ Roux limb. Arch Surg. 1992;127(3):295–300.PubMedCrossRef Miedema BW, Kelly KA. The Roux stasis syndrome. Treatment by pacing and prevention by use of an ‘uncut’ Roux limb. Arch Surg. 1992;127(3):295–300.PubMedCrossRef
15.
go back to reference Ou-Uti K, Sugiyama Y, Hada R. rho-Shaped anastomosis: a reconstruction of the alimentary tract after total gastrectomy. Am J Surg. 1979;137(3):332–7.PubMedCrossRef Ou-Uti K, Sugiyama Y, Hada R. rho-Shaped anastomosis: a reconstruction of the alimentary tract after total gastrectomy. Am J Surg. 1979;137(3):332–7.PubMedCrossRef
16.
go back to reference Hirao M, Kurokawa Y, Fujitani K, Tsujinaka T. Randomized controlled trial of Roux-en-Y versus rho-shaped-Roux-en-Y reconstruction after distal gastrectomy for gastric cancer. World J Surg. 2009;33(2):290–5.PubMedCrossRef Hirao M, Kurokawa Y, Fujitani K, Tsujinaka T. Randomized controlled trial of Roux-en-Y versus rho-shaped-Roux-en-Y reconstruction after distal gastrectomy for gastric cancer. World J Surg. 2009;33(2):290–5.PubMedCrossRef
17.
go back to reference NM Mimae T, Nishizaki M, Harano M, Aoki H, Onoda T, Shiozaki S, Oono S, Higaki K, Takakura N. Clinical study of Roux stasis syndrome after distal gastrectomy. Jpn Soc Gastroenterol Surg. 2008;41(8):1551–6.CrossRef NM Mimae T, Nishizaki M, Harano M, Aoki H, Onoda T, Shiozaki S, Oono S, Higaki K, Takakura N. Clinical study of Roux stasis syndrome after distal gastrectomy. Jpn Soc Gastroenterol Surg. 2008;41(8):1551–6.CrossRef
18.
go back to reference Bertucci W, Yadegar J, Takahashi A, et al. Antecolic laparoscopic Roux-en-Y gastric bypass is not associated with higher complication rates. Am Surg. 2005;71(9):735–7.PubMed Bertucci W, Yadegar J, Takahashi A, et al. Antecolic laparoscopic Roux-en-Y gastric bypass is not associated with higher complication rates. Am Surg. 2005;71(9):735–7.PubMed
19.
go back to reference Murakami Y, Uemura K, Sudo T, et al. An antecolic Roux-en Y type reconstruction decreased delayed gastric emptying after pylorus-preserving pancreatoduodenectomy. J Gastrointest Surg. 2008;12(6):1081–6.PubMedCrossRef Murakami Y, Uemura K, Sudo T, et al. An antecolic Roux-en Y type reconstruction decreased delayed gastric emptying after pylorus-preserving pancreatoduodenectomy. J Gastrointest Surg. 2008;12(6):1081–6.PubMedCrossRef
20.
go back to reference Tani M, Terasawa H, Kawai M, et al. Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial. Ann Surg. 2006;243(3):316–20.PubMedCrossRef Tani M, Terasawa H, Kawai M, et al. Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial. Ann Surg. 2006;243(3):316–20.PubMedCrossRef
21.
go back to reference Behrns KE, Sarr MG. Diagnosis and management of gastric emptying disorders. Adv Surg. 1994;27:233–55.PubMed Behrns KE, Sarr MG. Diagnosis and management of gastric emptying disorders. Adv Surg. 1994;27:233–55.PubMed
22.
go back to reference Cozzaglio L, Coladonato M, Dagrada CT, Doci R, Gennari L. [Does the Roux-en-Y-stasis syndrome still exist?]. Chir Ital. 2005;57(1):27–34.PubMed Cozzaglio L, Coladonato M, Dagrada CT, Doci R, Gennari L. [Does the Roux-en-Y-stasis syndrome still exist?]. Chir Ital. 2005;57(1):27–34.PubMed
23.
go back to reference Fraser SA, Shrier I, Miller G, Gordon PH. Immediate postlaparotomy small bowel obstruction: a 16-year retrospective analysis. Am Surg. 2002;68(9):780–2.PubMed Fraser SA, Shrier I, Miller G, Gordon PH. Immediate postlaparotomy small bowel obstruction: a 16-year retrospective analysis. Am Surg. 2002;68(9):780–2.PubMed
Metadata
Title
The flow angle beneath the gastrojejunostomy predicts delayed gastric emptying in Roux-en-Y reconstruction after distal gastrectomy
Authors
Toshihiko Masui
Toyonari Kubora
Yasutaka Nakanishi
Keiko Aoki
Shinichi Sugimoto
Michio Takamura
Hiroshi Takeda
Koji Hashimoto
Atsuo Tokuka
Publication date
01-07-2012
Publisher
Springer Japan
Published in
Gastric Cancer / Issue 3/2012
Print ISSN: 1436-3291
Electronic ISSN: 1436-3305
DOI
https://doi.org/10.1007/s10120-011-0107-4

Other articles of this Issue 3/2012

Gastric Cancer 3/2012 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.