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Lasers in Medical Science
Published in: Lasers in Medical Science 1/2022

01-02-2022 | Laser | Review Article

Mechanistic aspects of photobiomodulation therapy in the nervous system

Authors: Fatemeh Ramezani, Ali Neshasteh-Riz, Alireza Ghadaksaz, Seyedalireza Moghadas Fazeli, Atousa Janzadeh, Michael R. Hamblin

Published in: Lasers in Medical Science | Issue 1/2022

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Abstract

Photobiomodulation therapy (PBMT) previously known as low-level laser therapy (LLLT) has been used for over 30 years, to treat neurological diseases. Low-powered lasers are commonly used for clinical applications, although recently LEDs have become popular. Due to the growing application of this type of laser in brain and neural-related diseases, this review focuses on the mechanisms of laser action. The most important points to consider include the photon absorption by intracellular structures; the effect on the oxidative state of cells; and the effect on the expression of proteins involved in oxidative stress, inflammation, pain, and neuronal growth.
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Metadata
Title
Mechanistic aspects of photobiomodulation therapy in the nervous system
Authors
Fatemeh Ramezani
Ali Neshasteh-Riz
Alireza Ghadaksaz
Seyedalireza Moghadas Fazeli
Atousa Janzadeh
Michael R. Hamblin
Publication date
01-02-2022
Publisher
Springer London
Keyword
Laser
Published in
Lasers in Medical Science / Issue 1/2022
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-021-03277-2

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