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Published in: Lasers in Medical Science 8/2018

01-11-2018 | Original Article

Determining the optimal parameters of 420-nm intense pulsed light on Trichophyton rubrum growth in vitro

Authors: Hao Huang, Hongfeng Tang, Meiling Huang, Xiufen Zheng, Ruihua Wang, Yong Hu, Wenyi Lv

Published in: Lasers in Medical Science | Issue 8/2018

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Abstract

The effect of and the optimal parameters for intense pulsed light (IPL) with a 420-nm filter on an isolate of the fungus Trichophyton rubrum (T. rubrum) were examined in vitro. Colonies of T. rubrum were irradiated by using 420-nm IPL with various pulse numbers and energies. Colony areas were photographed and compared with those of untreated colonies to assess growth inhibition. Statistically significant inhibition of T. rubrum growth was detected in colonies treated with 12 pulses of greater than or equal to 12 J/cm2. The optimal parameters of 420-nm IPL were 12 pulses of 12 J/cm2. However, more in vitro and in vivo studies are necessary to investigate and explore this mechanism to determine whether IPL would have a potential use in the treatment of fungal infections of the skin.
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Metadata
Title
Determining the optimal parameters of 420-nm intense pulsed light on Trichophyton rubrum growth in vitro
Authors
Hao Huang
Hongfeng Tang
Meiling Huang
Xiufen Zheng
Ruihua Wang
Yong Hu
Wenyi Lv
Publication date
01-11-2018
Publisher
Springer London
Published in
Lasers in Medical Science / Issue 8/2018
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-018-2512-y

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