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Lasers in Medical Science
Published in: Lasers in Medical Science 4/2008

01-10-2008 | Original Article

The effects of laser irradiation on Trichophyton rubrum growth

Authors: Emre Vural, Harry L. Winfield, Alexander W. Shingleton, Thomas D. Horn, Gal Shafirstein

Published in: Lasers in Medical Science | Issue 4/2008

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Abstract

The effects of various laser wavelengths and fluences on the fungal isolate, Trichophyton rubrum, were examined in vitro. Standard-size isolates of T. rubrum were irradiated by using various laser systems. Colony areas were compared for growth inhibition on days 1, 3, and 6 after laser irradiation. Statistically significant growth inhibition of T. rubrum was detected in colonies treated with the 1,064-nm Q-switched Nd:YAG laser at 4 and 8 J/cm2 and 532-nm Q-switched Nd:YAG laser at 8 J/cm2. Q-switched Nd:YAG laser at 532- and 1,064-nm wavelengths produced significant inhibitory effect upon the fungal isolate T. rubrum in this in vitro study. However, more in vitro and in vivo studies are necessary to investigate if lasers would have a potential use in the treatment of fungal infections of skin and its adnexa.
Literature
1.
Arenas R, Dominguez-Cherit J, Fernandez LM (1995) Open randomized comparison of itraconazole versus terbinafine in onychomycosis. Int J Dermatol 34:138–143PubMedCrossRef
2.
Aly R, Hay RJ, Del Palacio A, Galimberti R (2000) Epidemiology of tinea capitis. Med Mycol 38:183–188PubMed
3.
Aman S, Haroon TS, Hussain I, Bokhari MA, Khurshid K (2001) Tinea unguium in Lahore, Pakistan. Med Mycol 39:177–180PubMedCrossRef
4.
Elewsk BE (2000) Tinea capitis: a current perspective. J Am Acad Dermatol 42:1–20CrossRef
5.
Evans EG (1998) Causative pathogens in onychomycosis and the possibility of treatment resistance: a review. J Am Acad Dermatol 38:S32–S36PubMedCrossRef
6.
Nweze EI (2001) Etiology of dermatophytoses amongst children in northeastern Nigeria. Med Mycol 39:181–184PubMedCrossRef
7.
Lesher JL Jr (1999) Oral therapy of common superficial fungal infections of the skin. J Am Acad Dermatol 40(6 pt 2):S31–S34PubMedCrossRef
8.
Koehler AM, Maibach HI (2001) Electronic monitoring in medication adherence measurement. Implications for dermatology. Am J Clin Dermatol 2:7–12PubMedCrossRef
9.
Scher RK (1999) Onychomycosis: therapeutic update. J Am Acad Dermatol 40(6 Pt 2):S21–S26PubMed
10.
Elewski BE (2000) Onychomycosis. Treatment, quality of life, and economic issues. Am J Clin Dermatol 1:19–26PubMedCrossRef
11.
Joish VN, Armstrong EP (2001) Which antifungal agent for onychomycosis? A pharmacoeconomic analysis. Pharmacoeconomics 19:983–1002PubMedCrossRef
12.
Kamp H, Tietz HJ, Lutz M, Piazena H, Sowyrda P, Lademann J, Blume-Peytavi U (2005) Antifungal effect of 5-aminolevulinic acid PDT in trichophyton rubrum. Mycoses 48:101–107PubMedCrossRef
13.
Smijs TG, van der Haas RN, Lugtenburg J, Liu Y, de Jong RL, Schuitmaker HJ (2004) Photodynamic treatment of the dermatophyte trichophyton rubrum and its microconidia with porphyrin photosensitizers. Photochem Photobiol 80:197–202PubMedCrossRef
14.
Smijs TG, Schuitmaker HJ (2003) Photodynamic inactivation of the dermatophyte Trichophyton rubrum. Photochem Photobiol 77:556–560PubMedCrossRef
15.
Tanzi EL, Lupton JR, Alster TS (2003) Lasers in dermatology: four decades of progress. J Am Acad Dermatol 49:1–31PubMedCrossRef
16.
Keates RH, Drago PC, Rothchild EJ (1988) Effect of excimer laser on microbiological organisms. Ophthalmic Surg 19:715–718PubMed
17.
Ouf SA, Abdel-Hady NF (1999) Influence of He–Ne laser irradiation of soybean seeds on seed mycoflora, growth, nodulation, and resistance to Fusarium solani. Folia Microbiol 44:388–396CrossRef
18.
Antony FC, Harland CC (2001) Red ink tattoo reactions: successful treatment with the Q-switched 532 nm Nd:YAG laser. Br J Dermatol 149:94–98CrossRef
19.
Gupta AK, Ahmad I, Borst I, Summebrbell RC (2000) Detection of xanthomegnin in epidermal materials infected with Trichophyton rubrum. J Invest Dermatol 115:901–905PubMedCrossRef
20.
Van Gemert MJ, Welch AJ, Pickering JW, Tan OT, Gijsbers GH (1995) Wavelengths for laser treatment of port wine stains and telangiectasia. Laser Surg Med 16:147–155CrossRef
21.
Bjerring P, Christiansen K, Troilius A (2003) Intense pulsed light source for the treatment of dye laser resistant port-wine stains. J Cosmet Laser Ther 5:7–13PubMedCrossRef
22.
Raulin C, Greve B, Grema H (2003) IPL Technology: a review. Laser Surg Med 32:78–87CrossRef
23.
Shafirstein G, Baumler W, Lapidoth M, Ferguson S, North PE, Waner M (2004) A new mathematical approach to the diffusion approximation theory for selective photothermolysis modeling and its implication in laser treatment of port-wine stains. Laser Surg Med 34:335–347CrossRef
24.
Wu-Yuan CD, Hashimoto T (1977) Architecture and chemistry of microconidial walls of trichophyton mentagrophytes. J Bacteriol 129:1584–1592PubMed
25.
Hashimoto T, Wu-Yuan CD, Blumenthal HJ (1976) Isolation and characterization of the rodlet layer of Trichophyton mentagrophytes microconidial wall. J Bacteriol 127:1543–1549PubMed
26.
Suthamjariya K, Farinelli WA, Koh W, Anderson RR (2004) Mechanisms of microvascular response to laser pulses. J Invest Dermatol 122:518–525PubMedCrossRef
27.
Alster TS (1999) Cutaneous resurfacing with CO2 and erbium: YAG lasers: preoperative, intraoperative and postoperative considerations. Plast Reconstr Surg 103:619–632PubMedCrossRef
Metadata
Title
The effects of laser irradiation on Trichophyton rubrum growth
Authors
Emre Vural
Harry L. Winfield
Alexander W. Shingleton
Thomas D. Horn
Gal Shafirstein
Publication date
01-10-2008
Publisher
Springer-Verlag
Published in
Lasers in Medical Science / Issue 4/2008
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-007-0492-4

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