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01-12-2016 | Original Article

Photobiomodulation therapy (PBMT) and/or cryotherapy in skeletal muscle restitution, what is better? A randomized, double-blinded, placebo-controlled clinical trial

Authors: Paulo Roberto Vicente de Paiva, Shaiane Silva Tomazoni, Douglas Scott Johnson, Adriane Aver Vanin, Gianna Móes Albuquerque-Pontes, Caroline dos Santos Monteiro Machado, Heliodora Leão Casalechi, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior

Published in: Lasers in Medical Science | Issue 9/2016

Abstract

Cryotherapy for post-exercise recovery remains widely used despite the lack of quality evidence. Photobiomodulation therapy (PBMT) studies (with both low-level laser therapy and light-emitting diode therapy) have demonstrated positive scientific evidence to suggest its use. The study aims to evaluate PBMT and cryotherapy as a single or combined treatment on skeletal muscle recovery after eccentric contractions of knee extensors. Fifty healthy male volunteers were recruited and randomized into five groups (PBMT, cryotherapy, cryotherapy + PBMT, PMBT + cryotherapy, or placebo) for a randomized, double-blinded, placebo-controlled trial that evaluated exercise performance (maximum voluntary contraction (MVC)), delayed onset muscle soreness (DOMS), and muscle damage (creatine kinase (CK)). Assessments were performed at baseline; immediately after; and at 1, 24, 48, 72, and 96 h. Comparator treatments was performed 3 min after exercise and repeated at 24, 48, and 72 h. PBMT was applied employing a cordless, portable GameDay^™ device (combination of 905 nm super-pulsed laser and 875- and 640-nm light-emitting diodes (LEDs); manufactured by Multi Radiance Medical^™, Solon - OH, USA), and cryotherapy by flexible rubber ice packs. PBMT alone was optimal for post-exercise recovery with improved MVC, decreased DOMS, and CK activity (p < 0.05) from 24 to 96 h compared to placebo, cryotherapy, and cryotherapy + PBMT. In the PBMT + cryotherapy group, the effect of PBMT was decreased (p > 0.05) but demonstrated significant improvement in MVC, decreased DOMS, and CK activity (p < 0.05). Cryotherapy as single treatment and cryotherapy + PBMT were similar to placebo (p > 0.05). We conclude that PBMT used as single treatment is the best modality for enhancement of post-exercise restitution, leading to complete recovery to baseline levels from 24 h after high-intensity eccentric contractions.

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Title: Photobiomodulation therapy (PBMT) and/or cryotherapy in skeletal muscle restitution, what is better? A randomized, double-blinded, placebo-controlled clinical trial
Authors: Paulo Roberto Vicente de Paiva
Shaiane Silva Tomazoni
Douglas Scott Johnson
Adriane Aver Vanin
Gianna Móes Albuquerque-Pontes
Caroline dos Santos Monteiro Machado
Heliodora Leão Casalechi
Paulo de Tarso Camillo de Carvalho
Ernesto Cesar Pinto Leal-Junior
Publication date: 01-12-2016
Publisher: Springer London
Published in: Lasers in Medical Science / Issue 9/2016
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-016-2071-z

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Photobiomodulation therapy (PBMT) and/or cryotherapy in skeletal muscle restitution, what is better? A randomized, double-blinded, placebo-controlled clinical trial

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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