Top

Published in:

01-11-2014 | Original Article

Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes

Authors: Fernanda Colella Antonialli, Thiago De Marchi, Shaiane Silva Tomazoni, Adriane Aver Vanin, Vanessa dos Santos Grandinetti, Paulo Roberto Vicente de Paiva, Henrique Dantas Pinto, Eduardo Foschini Miranda, Paulo de Tarso Camillo de Carvalho, Ernesto Cesar Pinto Leal-Junior

Published in: Lasers in Medical Science | Issue 6/2014

Abstract

Recent studies with phototherapy have shown positive results in enhancement of performance and improvement of recovery when applied before exercise. However, several factors still remain unknown such as therapeutic windows, optimal treatment parameters, and effects of combination of different light sources (laser and LEDs). The aim of this study was to evaluate the effects of phototherapy with the combination of different light sources on skeletal muscle performance and post-exercise recovery, and to establish the optimal energy dose. A randomized, double-blinded, placebo-controlled trial with participation of 40 male healthy untrained volunteers was performed. A single phototherapy intervention was performed immediately after pre-exercise (baseline) maximum voluntary contraction (MVC) with a cluster of 12 diodes (4 of 905 nm lasers—0.3125 mW each, 4 of 875 nm LEDs—17.5 mW each, and 4 of 670 nm LEDs—15 mW each- manufactured by Multi Radiance Medical™) and dose of 10, 30, and 50 J or placebo in six sites of quadriceps. MVC, delayed onset muscle soreness (DOMS), and creatine kinase (CK) activity were analyzed. Assessments were performed before, 1 min, 1, 24, 48, 72, and 96 h after eccentric exercise protocol employed to induce fatigue. Phototherapy increased (p < 0.05) MVC was compared to placebo from immediately after to 96 h after exercise with 10 or 30 J doses (better results with 30 J dose). DOMS was significantly decreased compared to placebo (p < 0.05) with 30 J dose from 24 to 96 h after exercise, and with 50 J dose from immediately after to 96 h after exercise. CK activity was significantly decreased (p < 0.05) compared to placebo with all phototherapy doses from 1 to 96 h after exercise (except for 50 J dose at 96 h). Pre-exercise phototherapy with combination of low-level laser and LEDs, mainly with 30 J dose, significantly increases performance, decreases DOMS, and improves biochemical marker related to skeletal muscle damage.

Goldman JA, Chiapella J, Casey H, Bass N, Graham J, McClatchey W, Dronavalli RV, Brown R, Bennett WJ, Miller SB, Wilson CH, Pearson B, Haun C, Persinski L, Huey H, Muckerheide M (1980) Laser therapy of rheumatoid arthritis. Lasers Surg Med 1:93–101PubMedCrossRef

Hegedus B, Viharos L, Gervain M, Gálfi M (2009) The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial. Photomed Laser Surg 27:577–584PubMedCrossRefPubMedCentral

Bjordal JM, Lopes-Martins RA, Iversen VV (2006) A randomised, placebo controlled trial of low level laser therapy for activated Achilles tendinitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations. Br J Sports Med 40:76–80PubMedCrossRefPubMedCentral

Stergioulas A, Stergioula M, Aarskog R, Lopes-Martins RA, Bjordal JM (2008) Effects of low-level laser therapy and eccentric exercises in the treatment of recreational athletes with chronic Achilles tendinopathy. Am J Sports Med 36:881–887PubMedCrossRef

Basford JR, Sheffield CG, Harmsen WS (1999) Laser therapy: a randomized, controlled trial of the effects of low-intensity Nd:YAG laser irradiation on musculoskeletal back pain. Arch Phys Med Rehabil 80:647–652PubMedCrossRef

Konstantinovic LM, Kanjuh ZM, Milovanovic AN, Cutovic MR, Djurovic AG, Savic VG, Dragin AS, Milovanovic ND (2010) Acute low back pain with radiculopathy: a double-blind, randomized, placebo-controlled study. Photomed Laser Surg 28:553–560PubMedCrossRef

Gur A, Sarac AJ, Cevik R, Altindag O, Sarac S (2004) Efficacy of 904 nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: a double-blind and randomize-controlled trial. Lasers Surg Med 35:229–235PubMedCrossRef

Chow RT, Heller GZ, Barnsley L (2006) The effect of 300 mW, 830 nm laser on chronic neck pain: a double-blind, randomized, placebo-controlled study. Pain 124:201–210PubMedCrossRef

Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM (2009) Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials. Lancet 374:1897–1908PubMedCrossRef

10.

Leal Junior EC, Lopes-Martins RA, Dalan F, Ferrari M, Sbabo FM, Generosi RA, Baroni BM, Penna SC, Iversen VV, Bjordal JM (2008) Effect of 655-nm low-level laser therapy on exercise-induced skeletal muscle fatigue in humans. Photomed Laser Surg 26:419–424PubMedCrossRef

11.

de Almeida P, Lopes-Martins RA, De Marchi T, Tomazoni SS, Albertini R, Corrêa JC, Rossi RP, Machado GP, da Silva DP, Bjordal JM, Leal Junior EC (2012) Red (660 nm) and infrared (830 nm) low-level laser therapy in skeletal muscle fatigue in humans: what is better? Lasers Med Sci 27:453–458PubMedCrossRefPubMedCentral

12.

Leal Junior EC, Lopes-Martins RA, Vanin AA, Baroni BM, Grosselli D, De Marchi T, Iversen VV, Bjordal JM (2009) Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans. Lasers Med Sci 24:425–431PubMedCrossRef

13.

Leal Junior EC, Lopes-Martins RA, Frigo L, De Marchi T, Rossi RP, de Godoi V, Tomazoni SS, da Silva DP, Basso M, Lotti Filho P, Corsetti FV, Iversen VV, Bjordal JM (2010) Effects of low-level laser therapy (LLLT) in the development of exercise-induced skeletal muscle fatigue and changes in biochemical markers related to post-exercise recovery. J Orthop Sports Phys Ther 40:524–532PubMedCrossRef

14.

De Marchi T, Leal Junior EC, Bortoli C, Tomazoni SS, Lopes-Martins RA, Salvador M (2012) Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress. Lasers Med Sci 27:231–236PubMedCrossRef

15.

Dos Santos Maciel T, Muñoz IS, Nicolau RA, Nogueira DV, Hauck LA, Osório RA, de Paula Júnior AR (2013) Phototherapy effect on the muscular activity of regular physical activity practitioners. Lasers Med Sci 29:1145–1152PubMedCrossRef

16.

Leal Junior EC, Lopes-Martins RA, Baroni BM, De Marchi T, Rossi RP, Grosselli D, Generosi RA, de Godoi V, Basso M, Mancalossi JL, Bjordal JM (2009) Comparison between single-diode low-level laser therapy (LLLT) and LED multi-diode (cluster) therapy (LEDT) applications before high-intensity exercise. Photomed Laser Surg 27:617–623PubMedCrossRef

17.

Leal Junior EC, Lopes-Martins RA, Rossi RP, De Marchi T, Baroni BM, de Godoi V, Marcos RL, Ramos L, Bjordal JM (2009) Effect of cluster multi-diode light emitting diode therapy (LEDT) on exercise-induced skeletal muscle fatigue and skeletal muscle recovery in humans. Lasers Surg Med 41:572–577PubMedCrossRef

18.

Borges LS, Cerqueira MS, Dos Santos Rocha JA, Conrado LA, Machado M, Pereira R, Neto OP (2013) Light-emitting diode phototherapy improves muscle recovery after a damaging exercise. Lasers Med Sci 29:1139–1144PubMed

19.

Miranda EF, Leal Junior EC, Marchetti PH, Dal Corso S (2014) Acute effects of light emitting diodes therapy (LEDT) in muscle function during isometric exercise in patients with chronic obstructive pulmonary disease: preliminary results of a randomized controlled trial. Lasers Med Sci 29:359–365PubMedCrossRef

20.

Borsa PA, Larkin KA, True JM (2013) Does phototherapy enhance skeletal muscle contractile function and postexercise recovery? A systematic review. J Athl Train 48:57–67PubMedPubMedCentral

21.

Leal Junior EC, Vanin AA, Miranda EF, de Carvalho PT, Dal Corso S, Bjordal JM (2013) Effect of phototherapy (low-level laser therapy and light-emitting diode therapy) on exercise performance and markers of exercise recovery: a systematic review with meta-analysis. Lasers Med Sci. doi:10.1007/s10103-013-1465-4

22.

Joensen J, Demmink JH, Johnson MI, Iversen VV, Lopes-Martins RÁ, Bjordal JM (2011) The thermal effects of therapeutic lasers with 810 and 904 nm wavelengths on human skin. Photomed Laser Surg 29:145–153PubMedCrossRef

23.

de Oliveira AR, Vanin AA, De Marchi T, Antonialli FC, Grandinetti VD, de Paiva PR, Albuquerque Pontes GM, Santos LA, Aleixo ID Jr, de Carvalho PD, Bjordal JM, Leal Junior EC (2014) What is the ideal dose and power output of low-level laser therapy (810 nm) on muscle performance and post-exercise recovery? Study protocol for a double-blind, randomized, placebo-controlled trial. Trials 15:69PubMedCrossRefPubMedCentral

24.

Baroni BM, Leal Junior EC, De Marchi T, Lopes AL, Salvador M, Vaz MA (2010) Low level laser therapy before eccentric exercise reduces muscle damage markers in humans. Eur J Appl Physiol 110:789–796PubMedCrossRef

25.

Huang YY, Chen AC, Carrol JD (2009) Biphasic dose response in low level light therapy. Dose Response 7:358–383PubMedCrossRefPubMedCentral

26.

Leal Junior EC, Lopes-Martins RA, de Almeida P, Ramos L, Iversen VV, Bjordal JM (2010) Effect of low-level laser therapy (GaAs 904 nm) in skeletal muscle fatigue and biochemical markers of muscle damage in rats. Eur J Appl Physiol 108:1083–1088PubMedCrossRef

27.

de Almeida P, Lopes-Martins RÁ, Tomazoni SS, Silva JA Jr, de Carvalho PT, Bjordal JM, Leal Junior EC (2011) Low-level laser therapy improves skeletal muscle performance, decreases skeletal muscle damage and modulates mRNA expression of COX-1 and COX-2 in a dose-dependent manner. Photochem Photobiol 87:1159–1163PubMedCrossRef

28.

Santos LA, Marcos RL, Tomazoni SS, Vanin AA, Antonialli FC, Grandinetti VS, Albuquerque-Pontes GM, Paiva PR, Lopes-Martins RA, de Carvalho PT, Bjordal JM, Leal Junior EC (2014) Effects of pre-irradiation of low-level laser therapy with different doses and wavelengths in skeletal muscle performance, fatigue and skeletal muscle damage induced by tetanic contractions in rats. Lasers Med Sci. doi:10.1007/s10103-014-1560-1

29.

Tullberg M, Alstergren PJ, Ernberg MM (2003) Effects of low-power laser exposure on masseter muscle pain and microcirculation. Pain 105:89–96PubMedCrossRef

30.

Silveira PC, Silva LA, Fraga DB, Freitas TP, Streck EL, Pinho R (2009) Evaluation of mitochondrial respiratory chain activity in muscle healing by low-level laser therapy. J Photochem Photobiol B 95:89–92PubMedCrossRef

31.

Xu X, Zhao X, Liu TC, Pan H (2008) Low-intensity laser irradiation improves the mitochondrial dysfunction of C2C12 induced by electrical stimulation. Photomed Laser Surg 26:197–202PubMedCrossRef

32.

Avni D, Levkovitz S, Maltz L, Oron U (2005) Protection of skeletal muscles from ischemic injury: low-level laser therapy increases antioxidant activity. Photomed Laser Surg 23:273–277PubMedCrossRef

33.

Rizzi CF, Mauriz JL, Freitas Correa DS, Moreira AJ, Zettler CG, Filippin LI, Marroni NP, González-Gallego J (2006) Effects of low-level laser therapy (LLLT) on the nuclear factor (NF)-kappaB signaling pathway in traumatized muscle. Lasers Surg Med 38:704–713PubMedCrossRef

34.

Hayworth CR, Rojas JC, Padilla E, Holmes GM, Sheridan EC, Gonzalez-Lima F (2010) In vivo low-level light therapy increases cytochrome oxidase in skeletal muscle. Photochem Photobiol 86:673–680PubMedCrossRef

Title: Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes
Authors: Fernanda Colella Antonialli
Thiago De Marchi
Shaiane Silva Tomazoni
Adriane Aver Vanin
Vanessa dos Santos Grandinetti
Paulo Roberto Vicente de Paiva
Henrique Dantas Pinto
Eduardo Foschini Miranda
Paulo de Tarso Camillo de Carvalho
Ernesto Cesar Pinto Leal-Junior
Publication date: 01-11-2014
Publisher: Springer London
Published in: Lasers in Medical Science / Issue 6/2014
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-014-1611-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Phototherapy in skeletal muscle performance and recovery after exercise: effect of combination of super-pulsed laser and light-emitting diodes

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 6/2014

Raman spectroscopic study of the repair of surgical bone defects grafted or not with biphasic synthetic micro-granular HA + β-calcium triphosphate irradiated or not with λ850 nm LED light

Effects of low-level laser therapy on mitochondrial respiration and nitrosyl complex content

Adjunctive use of combination of super-pulsed laser and light-emitting diodes phototherapy on nonspecific knee pain: double-blinded randomized placebo-controlled trial

The influence of low-level laser therapy on parameters of oxidative stress and DNA damage on muscle and plasma in rats with heart failure

Effects of laser irradiation at different wavelengths (660, 810, 980, and 1,064 nm) on mucositis in an animal model of wound healing

Prevention of dentine caries using silver diamine fluoride application followed by Er:YAG laser irradiation: an in vitro study