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Lasers in Medical Science
Published in: Lasers in Medical Science 1/2009

01-01-2009 | Original article

Effect of low-intensity laser therapy on mast cell degranulation in human oral mucosa

Authors: Iris Sawasaki, Vinicius R. Geraldo-Martins, Martha S. Ribeiro, Márcia M. Marques

Published in: Lasers in Medical Science | Issue 1/2009

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Abstract

Little is known about the physiological mechanisms related to low-intensity laser therapy (LILT), particularly in acute inflammation and subsequent wound healing. The objective of this study was to verify the effect of LILT on mast cell degranulation. Epulis fissuratum tissues from eight patients were used. One part of the lesion was irradiated with an AsGaAl laser (λ =  670 nm, 8.0 J/cm2, 5 mW, 4 min). The other part was not irradiated. Then, the specimens were immediately removed, fixed and examined by light microscopy. The number of mast cells was similar in laser-treated samples when compared with non-irradiated specimens. The degranulation indexes of the mast cells observed in the irradiated samples were significantly higher than those of controls (P < 0.05). LILT with the parameters used increased the number of degranulated mast cells in oral mucosa.
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Metadata
Title
Effect of low-intensity laser therapy on mast cell degranulation in human oral mucosa
Authors
Iris Sawasaki
Vinicius R. Geraldo-Martins
Martha S. Ribeiro
Márcia M. Marques
Publication date
01-01-2009
Publisher
Springer-Verlag
Published in
Lasers in Medical Science / Issue 1/2009
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI
https://doi.org/10.1007/s10103-007-0531-1

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