Published in:
Open Access
01-01-2018 | Editorial
An era of biological treatment in systemic lupus erythematosus
Authors:
Jing He, Zhanguo Li
Published in:
Clinical Rheumatology
|
Issue 1/2018
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Excerpt
The management of active SLE is challenging due to the heterogeneous nature of the disease and lack of specific treatment. Current therapy of active SLE primarily relies on corticosteroids and immunosuppressants [
1]. Complete remission is the ultimate goal in SLE treatment, but it is not common in daily practice [
2]. The routine therapy of corticosteroid and immunosuppressant is only effective in a portion of patients and associated with substantial adverse effects including infections, osteoporosis, and cardiovascular disorders [
3‐
5]. Therefore, there is an unmet need for new therapies with better efficacy and less adverse effects. …