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Clinical Rheumatology
Published in: Clinical Rheumatology 1/2005

01-02-2005 | Case Report

p-ANCA-associated periaortitis with histological proof of Wegener’s granulomatosis: case report

Authors: T. Carels, E. Verbeken, D. Blockmans

Published in: Clinical Rheumatology | Issue 1/2005

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Abstract

We describe a 63-year-old man who presented with an inflammatory aortic aneurysm. The patient had p-ANCA antibodies directed against myeloperoxidase. A diagnosis of idiopathic periaortitis was made. Seven years later, he was rehospitalized because of fever, weight loss, and polyneuropathy. After revision of the aortic biopsy, which showed necrotizing vasculitis with palisading granuloma, a diagnosis of Wegener’s granulomatosis (WG) was made. This case report illustrates an unusual disease course in WG, resembling large vessel vasculitis, and we discuss the possible mechanisms of large vessel involvement in this form of vasculitis.
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Metadata
Title
p-ANCA-associated periaortitis with histological proof of Wegener’s granulomatosis: case report
Authors
T. Carels
E. Verbeken
D. Blockmans
Publication date
01-02-2005
Publisher
Springer-Verlag
Published in
Clinical Rheumatology / Issue 1/2005
Print ISSN: 0770-3198
Electronic ISSN: 1434-9949
DOI
https://doi.org/10.1007/s10067-004-0998-0

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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