Skip to main content
Top
Published in: Hernia 5/2016

Open Access 01-10-2016 | Original Article

Is there a place for a biological mesh in perineal hernia repair?

Authors: G. D. Musters, O. Lapid, J. Stoker, B. F. Musters, W. A. Bemelman, P. J. Tanis

Published in: Hernia | Issue 5/2016

Login to get access

Abstract

Purpose

This study aimed to determine the outcome of perineal hernia repair with a biological mesh after abdominoperineal resection (APR).

Method

All consecutive patients who underwent perineal hernia repair with a porcine acellular dermal mesh between 2010 and 2014 were included. Follow-up was performed by clinical examination and MRI.

Results

Fifteen patients underwent perineal hernia repair after a median of 25 months from APR. Four patients had a concomitant contaminated perineal defect, for which a gluteal fasciocutaneous flap was added in three patients. Wound infection occurred in three patients. After a median follow-up of 17 months (IQR 12–24), a clinically recurrent perineal hernia developed in 7 patients (47 %): 6 of 11 patients after a non-cross-linked mesh and 1 of 4 patients after a cross-linked mesh (p = 0.57). Routine MRI at a median of 17 months revealed a recurrent perineal hernia in 7 of 10 evaluable patients, with clinical confirmation of recurrence in 5 of these 7 patients. No recurrent hernia was observed in the three patients with combined flap reconstruction for contaminated perineal defects.

Conclusion

A high recurrence rate was observed after biological mesh repair of a perineal hernia following APR.
Literature
1.
go back to reference Musters GD, Buskens CJ, Bemelamn WA, Tanis PJ (2014) Perineal wound healing after abdominoperineal resection for rectal cancer; a systematic review and meta-analysis. Dis Colon Rectum 57:1129–1139CrossRefPubMed Musters GD, Buskens CJ, Bemelamn WA, Tanis PJ (2014) Perineal wound healing after abdominoperineal resection for rectal cancer; a systematic review and meta-analysis. Dis Colon Rectum 57:1129–1139CrossRefPubMed
2.
go back to reference Sayers AE, Patel RK, Hunter IA (2014) Perineal hernia formation following extralevator abdominoperineal excision. Colorectal Dis 17:351–355CrossRef Sayers AE, Patel RK, Hunter IA (2014) Perineal hernia formation following extralevator abdominoperineal excision. Colorectal Dis 17:351–355CrossRef
3.
go back to reference Mjoli M, Sloothaak DA, Buskens CJ, Bemelman WA, Tanis PJ (2012) Perineal hernia repair after abdominoperineal resection: a pooled analysis. Colorectal Dis 14(7):400–406CrossRef Mjoli M, Sloothaak DA, Buskens CJ, Bemelman WA, Tanis PJ (2012) Perineal hernia repair after abdominoperineal resection: a pooled analysis. Colorectal Dis 14(7):400–406CrossRef
4.
go back to reference Burns NK, Jaffari MV, Rios CN, Mathur AB, Butler CE (2010) Non-cross-linked porcine acellular dermal matrices for abdominal wall reconstruction. Plast Reconstr Surg 125:167–176CrossRefPubMed Burns NK, Jaffari MV, Rios CN, Mathur AB, Butler CE (2010) Non-cross-linked porcine acellular dermal matrices for abdominal wall reconstruction. Plast Reconstr Surg 125:167–176CrossRefPubMed
5.
go back to reference Rosen MJ (2010) Biologic mesh for abdominal wall reconstruction: a critical appraisal. Am Surg 76:1–6PubMed Rosen MJ (2010) Biologic mesh for abdominal wall reconstruction: a critical appraisal. Am Surg 76:1–6PubMed
6.
go back to reference de Campos FG, Habr-Gama A, Araujo SE, Sousa AH Jr, Nahas CR, Lupinacci RM et al (2005) Incidence and management of perineal hernia after laparoscopic proctectomy. Surg Laparosc Endosc Percutan Tech 15:366–370CrossRefPubMed de Campos FG, Habr-Gama A, Araujo SE, Sousa AH Jr, Nahas CR, Lupinacci RM et al (2005) Incidence and management of perineal hernia after laparoscopic proctectomy. Surg Laparosc Endosc Percutan Tech 15:366–370CrossRefPubMed
7.
go back to reference Kathju S, Lasko LA, Medich DS (2011) Perineal hernia repair with acellular dermal graft and suture anchor fixation. Hernia 15(3):357–360CrossRefPubMed Kathju S, Lasko LA, Medich DS (2011) Perineal hernia repair with acellular dermal graft and suture anchor fixation. Hernia 15(3):357–360CrossRefPubMed
8.
go back to reference Skipworth RJ, Smith GH, Anderson DN (2007) Secondary perineal hernia following open abdominoperineal excision of the rectum: report of a case and review of the literature. Hernia 11:541–545CrossRefPubMed Skipworth RJ, Smith GH, Anderson DN (2007) Secondary perineal hernia following open abdominoperineal excision of the rectum: report of a case and review of the literature. Hernia 11:541–545CrossRefPubMed
9.
go back to reference Chelala E, Declercq S (2015) Laparoscopic repair of post-abdominoperineal resection hernia: biological mesh and augmentation technique. Hernia 19:853–856CrossRefPubMed Chelala E, Declercq S (2015) Laparoscopic repair of post-abdominoperineal resection hernia: biological mesh and augmentation technique. Hernia 19:853–856CrossRefPubMed
10.
go back to reference Martijnse IS, Holman F, Nieuwenhuijzen GA, Rutten HJ, Nienhuijs SW (2012) Perineal hernia repair after abdominoperineal rectal excision. Dis Colon Rectum 55:90–95CrossRefPubMed Martijnse IS, Holman F, Nieuwenhuijzen GA, Rutten HJ, Nienhuijs SW (2012) Perineal hernia repair after abdominoperineal rectal excision. Dis Colon Rectum 55:90–95CrossRefPubMed
12.
go back to reference Akatsu T, Murai S, Kamiya S, Kojima K, Mizuhashi Y, Hasegawa H et al (2009) Perineal hernia as a rare complication after laparoscopic abdominoperineal resection: report of a case. Surg Today 39:340–343CrossRefPubMed Akatsu T, Murai S, Kamiya S, Kojima K, Mizuhashi Y, Hasegawa H et al (2009) Perineal hernia as a rare complication after laparoscopic abdominoperineal resection: report of a case. Surg Today 39:340–343CrossRefPubMed
13.
go back to reference Frydman GM, Polglase AL (1989) Perineal approach for polypropylene mesh repair of perineal hernia. Aust N Z J Surg 59:895–897CrossRefPubMed Frydman GM, Polglase AL (1989) Perineal approach for polypropylene mesh repair of perineal hernia. Aust N Z J Surg 59:895–897CrossRefPubMed
15.
go back to reference Ryan S, Kavanagh DO, Neary PC (2010) Laparoscopic repair of postoperative perineal hernia. Case Rep Med 9:2010 Ryan S, Kavanagh DO, Neary PC (2010) Laparoscopic repair of postoperative perineal hernia. Case Rep Med 9:2010
16.
go back to reference Abbas Y, Garner J (2014) Laparoscopic and perineal approaches to perineal hernia repair. Tech Coloproctol 18:361–364CrossRefPubMed Abbas Y, Garner J (2014) Laparoscopic and perineal approaches to perineal hernia repair. Tech Coloproctol 18:361–364CrossRefPubMed
17.
go back to reference Allen SK, Schwab K, Day A, Singh-Ranger D, Rockall TA (2014) Laparoscopic repair of post-operative perineal hernia using a two-mesh technique. Colorectal Dis 17:70–73CrossRef Allen SK, Schwab K, Day A, Singh-Ranger D, Rockall TA (2014) Laparoscopic repair of post-operative perineal hernia using a two-mesh technique. Colorectal Dis 17:70–73CrossRef
18.
go back to reference Novitsky YW (2013) Biology of biological meshes used in hernia repair. Surg Clin North Am 93:1211–1215CrossRefPubMed Novitsky YW (2013) Biology of biological meshes used in hernia repair. Surg Clin North Am 93:1211–1215CrossRefPubMed
19.
go back to reference Gu Q, Wang D, Gao Y, Zhou J, Peng R, Cui Y et al (2002) Expression of MMP1 in surgical and radiation-impaired wound healing and its effects on the healing process. J Environ Pathol Toxicol Oncol 21:71–78CrossRefPubMed Gu Q, Wang D, Gao Y, Zhou J, Peng R, Cui Y et al (2002) Expression of MMP1 in surgical and radiation-impaired wound healing and its effects on the healing process. J Environ Pathol Toxicol Oncol 21:71–78CrossRefPubMed
20.
go back to reference Herskind C, Bamberg M, Rodemann HP (1998) The role of cytokines in the development of normal-tissue reactions after radiotherapy. Strahlenther Onkol 174:12–15PubMed Herskind C, Bamberg M, Rodemann HP (1998) The role of cytokines in the development of normal-tissue reactions after radiotherapy. Strahlenther Onkol 174:12–15PubMed
21.
go back to reference Johnson LB, Jorgensen LN, Adawi D, Blomqvist P, Asklof GB, Gottrup F et al (2005) The effect of preoperative radiotherapy on systemic collagen deposition and postoperative infective complications in rectal cancer patients. Dis Colon Rectum 48:1573–1580CrossRefPubMed Johnson LB, Jorgensen LN, Adawi D, Blomqvist P, Asklof GB, Gottrup F et al (2005) The effect of preoperative radiotherapy on systemic collagen deposition and postoperative infective complications in rectal cancer patients. Dis Colon Rectum 48:1573–1580CrossRefPubMed
22.
go back to reference Deeken CR, Melman L, Jenkins ED, Greco SC, Frisella MM, Matthews BD (2011) Histologic and biomechanical evaluation of crosslinked and non-crosslinked biologic meshes in a porcine model of ventral incisional hernia repair. J Am Coll Surg 212:880–888CrossRefPubMedPubMedCentral Deeken CR, Melman L, Jenkins ED, Greco SC, Frisella MM, Matthews BD (2011) Histologic and biomechanical evaluation of crosslinked and non-crosslinked biologic meshes in a porcine model of ventral incisional hernia repair. J Am Coll Surg 212:880–888CrossRefPubMedPubMedCentral
23.
go back to reference de Castro Bras LE, Shurey S, Sibbons PD (2012) Evaluation of crosslinked and non-crosslinked biologic prostheses for abdominal hernia repair. Hernia 16:77–89CrossRefPubMed de Castro Bras LE, Shurey S, Sibbons PD (2012) Evaluation of crosslinked and non-crosslinked biologic prostheses for abdominal hernia repair. Hernia 16:77–89CrossRefPubMed
24.
go back to reference Oliver RF, Grant RA, Cox RW, Hulme MJ, Mudie A (1976) Histological studies of subcutaneous and intraperitoneal implants of trypsin-prepared dermal collagen allografts in the rat. Clin Orthop Relat Res 115:291–302PubMed Oliver RF, Grant RA, Cox RW, Hulme MJ, Mudie A (1976) Histological studies of subcutaneous and intraperitoneal implants of trypsin-prepared dermal collagen allografts in the rat. Clin Orthop Relat Res 115:291–302PubMed
25.
go back to reference Cornwell KG, Landsman A, James KS (2009) Extracellular matrix biomaterials for soft tissue repair. Clin Podiatr Med Surg 26:507–523CrossRefPubMed Cornwell KG, Landsman A, James KS (2009) Extracellular matrix biomaterials for soft tissue repair. Clin Podiatr Med Surg 26:507–523CrossRefPubMed
26.
go back to reference Liang HC, Chang Y, Hsu CK, Lee MH, Sung HW (2004) Effects of crosslinking degree of an acellular biological tissue on its tissue regeneration pattern. Biomaterials 25:3541–3552CrossRefPubMed Liang HC, Chang Y, Hsu CK, Lee MH, Sung HW (2004) Effects of crosslinking degree of an acellular biological tissue on its tissue regeneration pattern. Biomaterials 25:3541–3552CrossRefPubMed
27.
go back to reference Eriksen M, Bulut O (2014) Chemotherapy-induced enterocutaneous fistula after perineal hernia repair using a biological mesh: a case report. Int Med Case Rep J 7:11–13CrossRefPubMedPubMedCentral Eriksen M, Bulut O (2014) Chemotherapy-induced enterocutaneous fistula after perineal hernia repair using a biological mesh: a case report. Int Med Case Rep J 7:11–13CrossRefPubMedPubMedCentral
28.
go back to reference Christensen HK, Nerstrom P, Tei T, Laurberg S (2011) Perineal repair after extralevator abdominoperineal excision for low rectal cancer. Dis Colon Rectum 54:711–717CrossRefPubMed Christensen HK, Nerstrom P, Tei T, Laurberg S (2011) Perineal repair after extralevator abdominoperineal excision for low rectal cancer. Dis Colon Rectum 54:711–717CrossRefPubMed
29.
go back to reference Kavanagh DO, Imran H, Almoudaris A, Ziprin P, Faiz O (2012) Dynamic magnetic resonance imaging demonstrates the integrity of perineal reconstruction following cylindrical abdominoperineal excision with reconstruction of the pelvic floor using porcine collagen. Case Rep Med 2012:752357PubMedPubMedCentral Kavanagh DO, Imran H, Almoudaris A, Ziprin P, Faiz O (2012) Dynamic magnetic resonance imaging demonstrates the integrity of perineal reconstruction following cylindrical abdominoperineal excision with reconstruction of the pelvic floor using porcine collagen. Case Rep Med 2012:752357PubMedPubMedCentral
30.
go back to reference Mulder IM, Deerenberg EB, Bemelman WA, Jeekel J, Lange JF (2015) Infection susceptibility of crosslinked and non-crosslinked biological meshes in an experimental contaminated environment. Am J Surg 210(1):159–166CrossRefPubMed Mulder IM, Deerenberg EB, Bemelman WA, Jeekel J, Lange JF (2015) Infection susceptibility of crosslinked and non-crosslinked biological meshes in an experimental contaminated environment. Am J Surg 210(1):159–166CrossRefPubMed
31.
go back to reference Musters GD, Bemelman WA, Bosker RJ, Burger JW et al (2014) Randomized controlled multicentre study comparing biological mesh closure of the pelvic floor with primary perineal wound closure after extralevator abdominoperineal resection for rectal cancer (BIOPEX-study). BMC Surg 14:58CrossRefPubMedPubMedCentral Musters GD, Bemelman WA, Bosker RJ, Burger JW et al (2014) Randomized controlled multicentre study comparing biological mesh closure of the pelvic floor with primary perineal wound closure after extralevator abdominoperineal resection for rectal cancer (BIOPEX-study). BMC Surg 14:58CrossRefPubMedPubMedCentral
Metadata
Title
Is there a place for a biological mesh in perineal hernia repair?
Authors
G. D. Musters
O. Lapid
J. Stoker
B. F. Musters
W. A. Bemelman
P. J. Tanis
Publication date
01-10-2016
Publisher
Springer Paris
Published in
Hernia / Issue 5/2016
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-016-1504-8

Other articles of this Issue 5/2016

Hernia 5/2016 Go to the issue