Top

Published in:

01-12-2006 | Review

Effect of lifestyle, gender and age on collagen formation and degradation

Author: Lars Tue Sørensen

Published in: Hernia | Issue 6/2006

Abstract

Historically, inappropriate lifestyle with an inadequate dietary intake of vitamin C has been associated with poor wound healing as a clinical manifestation of scurvy. In modern times, clinical evidence produced over the past few decades indicates that a modern lifestyle factor, such as smoking, together with biologic characteristics, like old age and male gender, are risk factors for abdominal wall hernia and recurrence. The pathologic pathways for these clinical observations are unclear. Yet, evidence from animal and human studies suggests that these exogenous and endogenous factors may have a negative impact on collagen metabolism, enhancing degradation and impairing formation.

Walter R, Robins B (1974) A voyage round the world in the years MDC–MCXL, I, II, III, IV by George Anson. Oxford University Press, London, pp 106–107

Stewart CP, Guthrie D (eds) (1953) Lind’s treatise on scurvy, a bicentennial volume containing a reprint of the first edition of A treatise on scurvy by James Lind, MD with additional notes. Edinburgh University Press, Edinburgh, pp 113–126

Hirschmann JV, Raugi GJ (1999) Adult scurvy. J Am Acad Dermatol 41(6):895–906PubMedCrossRef

Sorensen LT, Jorgensen LN, Gottrup F (2003) Biochemical aspects of abdominal wall hernia and recurrence. In: Fitzgibbons RJ Jr, Greenburg AG (eds) Nyhus and Condon’s hernia, 5th edn. Lippincott William & Wilkins, Philadelphia, Pennsylvania, pp 9–16

Bevelaqua FA, Hasselbacher P, Schumacher HR (1976) Scurvy and hemarthrosis. JAMA 235(17):1874–1876PubMedCrossRef

Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P (2002) Molecular biology of the cell, 4th edn. Garland Science, New York

Lindholt JS, Jorgensen B, Klitgaard NA, Henneberg EW (2003) Systemic levels of cotinine and elastase, but not pulmonary function, are associated with the progression of small abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 26(4):418–422PubMedCrossRef

van Laarhoven CJ, Borstlap AC, Berge Henegouwen DP, Palmen FM, Verpalen MC, Schoemaker MC (1993) Chronic obstructive pulmonary disease and abdominal aortic aneurysms. Eur J Vasc Surg 7(4):386–390PubMedCrossRef

Janoff A (1985) Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis 132(2):417–433PubMed

10.

Cannon DJ, Read RC (1981) Metastatic emphysema: a mechanism for acquiring inguinal herniation. Ann Surg 194(3):270–278PubMedCrossRef

11.

Sorensen LT, Hemmingsen U, Kallehave F, Wille-Jorgensen P, Kjaergaard J, Moller LN, Jorgensen T (2005) Risk factors for tissue and wound complications in gastrointestinal surgery. Ann Surg 241(4):654–658PubMedCrossRef

12.

Sorensen LT, Jorgensen T, Kirkeby LT, Skovdal J, Vennits B, Wille-Jorgensen P (1999) Smoking and alcohol abuse are major risk factors for anastomotic leakage in colorectal surgery. Br J Surg 86(7):927–931PubMedCrossRef

13.

Peivandi AA, Kasper-Konig W, Quinkenstein E, Loos AH, Dahm M (2003) Risk factors influencing the outcome after surgical treatment of complicated deep sternal wound complications. Cardiovasc Surg 11(3):207–212PubMedCrossRef

14.

Levin L, Schwartz-Arad D (2005) The effect of cigarette smoking on dental implants and related surgery. Implant Dent 14(4):357–361PubMed

15.

Spear SL, Ducic I, Cuoco F, Hannan C (2005) The effect of smoking on flap and donor-site complications in pedicled TRAM breast reconstruction. Plast Reconstr Surg 116(7):1873–1880PubMedCrossRef

16.

Moller AM, Pedersen T, Villebro N, Munksgaard A (2003) Effect of smoking on early complications after elective orthopaedic surgery. J Bone Joint Surg Br 85(2):178–181PubMedCrossRef

17.

Sorensen LT, Hemmingsen UB, Kirkeby LT, Kallehave F, Jorgensen LN (2005) Smoking is a risk factor for incisional hernia. Arch Surg 140(2):119–123PubMedCrossRef

18.

Junge K, Rosch R, Klinge U, Schwab R, Peiper C, Binnebosel M, Schenten F, Schumpelick V (2006) Risk factors related to recurrence in inguinal hernia repair: a retrospective analysis. Hernia 10(4):309–315PubMedCrossRef

19.

Sorensen LT, Friis E, Jorgensen T, Vennits B, Andersen BR, Rasmussen GI, Kjaergaard J (2002) Smoking is a risk factor for recurrence of groin hernia. World J Surg 26(4):397–400PubMedCrossRef

20.

Abrahamson J (1998) Etiology and pathophysiology of primary and recurrent groin hernia formation. Surg Clin North Am 78(6):953–972PubMedCrossRef

21.

Bielecki K, Pulawski R (1988) Is cigarette smoking a causative factor in the development of inguinal hernia? (in Polish). Pol Tyg Lek 43(30):974–976PubMed

22.

Knuutinen A, Kokkonen N, Risteli J, Vahakangas K, Kallioinen M, Salo T, Sorsa T, Oikarinen A (2002) Smoking affects collagen synthesis and extracellular matrix turnover in human skin. Br J Dermatol 146(4):588–594PubMedCrossRef

23.

Jorgensen LN, Kallehave F, Christensen E, Siana JE, Gottrup F (1998) Less collagen production in smokers. Surgery 123(4):450–455PubMed

24.

Lahmann C, Bergemann J, Harrison G, Young AR (2001) Matrix metalloproteinase-1 and skin ageing in smokers. Lancet 357(9260):935–936PubMedCrossRef

25.

Sorensen LT, Nielsen HB, Kharazmi A, Gottrup F (2004) Effect of smoking and abstention on oxidative burst and reactivity of neutrophils and monocytes. Surgery 136(5):1047–1053PubMedCrossRef

26.

Wong LS, Martins-Green M (2004) Firsthand cigarette smoke alters fibroblast migration and survival: implications for impaired healing. Wound Repair Regen 12(4):471–484PubMedCrossRef

27.

Yin L, Morita A, Tsuji T (2000) Alterations of extracellular matrix induced by tobacco smoke extract. Arch Dermatol Res 292(4):188–194PubMedCrossRef

28.

Lykkesfeldt J, Loft S, Nielsen JB, Poulsen HE (1997) Ascorbic acid and dehydroascorbic acid as biomarkers of oxidative stress caused by smoking. Am J Clin Nutr 65(4):959–963PubMed

29.

Richardson D (1987) Effects of tobacco smoke inhalation on capillary blood flow in human skin. Arch Environ Health 42(1):19–25PubMedCrossRef

30.

Jensen JA, Goodson WH, Williams H, Hunt TK (1991) Cigarette smoking decreases tissue oxygen. Arch Surg 126(9):1131–1134PubMed

31.

Sorensen LT, Jorgensen LN, Zillmer R, Vange J, Hemmingsen U, Gottrup F (2006) Transdermal nicotine patch enhances type I collagen synthesis in abstinent smokers. Wound Repair Regen 14(3):247–251PubMedCrossRef

32.

Jacobi J, Jang JJ, Sundram U, Dayoub H, Fajardo LF, Cooke JP (2002) Nicotine accelerates angiogenesis and wound healing in genetically diabetic mice. Am J Pathol 161(1):97–104PubMed

33.

Lykkesfeldt J, Christen S, Wallock LM, Chang HH, Jacob RA, Ames BN (2000) Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Am J Clin Nutr 71(2):530–536PubMed

34.

Vidovic D, Jurisic D, Franjic BD, Glavan E, Ledinsky M, Bekavac-Beslin M (2006) Factors affecting recurrence after incisional hernia repair. Hernia 10(4):322–325PubMedCrossRef

35.

Sauerland S, Korenkov M, Kleinen T, Arndt M, Paul A (2004) Obesity is a risk factor for recurrence after incisional hernia repair. Hernia 8(1):42–46PubMedCrossRef

36.

Dindo D, Muller MK, Weber M, Clavien PA (2003) Obesity in general elective surgery. Lancet 361(9374):2032–2035PubMedCrossRef

37.

Peacock EE Jr, Madden JW (1974) Studies on the biology and treatment of recurrent inguinal hernia. II. Morphological changes. Ann Surg 179(5):567–571PubMedCrossRef

38.

Conner WT, Peacock EE Jr (1973) Some studies on the etiology of inguinal hernia. Am J Surg 126(6):732–735PubMedCrossRef

39.

McArdle G (1997) Is inguinal hernia a defect in human evolution and would this insight improve concepts for methods of surgical repair? [see comments]. Clin Anat 10(1):47–55PubMedCrossRef

40.

Bucknall TE, Cox PJ, Ellis H (1982) Burst abdomen and incisional hernia: a prospective study of 1129 major laparotomies. Br Med J (Clin Res Ed) 284(6320):931–933CrossRef

41.

Carlson MA, Ludwig KA, Condon RE (1995) Ventral hernia and other complications of 1,000 midline incisions. South Med J 88(4):450–453PubMed

42.

Raffetto JD, Cheung Y, Fisher JB, Cantelmo NL, Watkins MT, Lamorte WW, Menzoian JO (2003) Incision and abdominal wall hernias in patients with aneurysm or occlusive aortic disease. J Vasc Surg 37(6):1150–1154PubMedCrossRef

43.

Adye B, Luna G (1998) Incidence of abdominal wall hernia in aortic surgery. Am J Surg 175(5):400–402PubMed

44.

Lehnert B, Wadouh F (1992) High coincidence of inguinal hernias and abdominal aortic aneurysms. Ann Vasc Surg 6(2):134–137PubMedCrossRef

45.

Cannon DJ, Casteel L, Read RC (1984) Abdominal aortic aneurysm, Leriche’s syndrome, inguinal herniation, and smoking. Arch Surg 119(4):387–389PubMed

46.

Rullier E, Laurent C, Garrelon JL, Michel P, Saric J, Parneix M (1998) Risk factors for anastomotic leakage after resection of rectal cancer. Br J Surg 85(3):355–358PubMedCrossRef

47.

Carlson MA (1997) Acute wound failure. Surg Clin North Am 77(3):607–636PubMedCrossRef

48.

Penninckx FM, Poelmans SV, Kerremans RP, Beckers JP (1979) Abdominal wound dehiscence in gastroenterological surgery. Ann Surg 189(3):345–352PubMedCrossRef

49.

Castelo-Branco C, Pons F, Gratacos E, Fortuny A, Vanrell JA, Gonzalez-Merlo J (1994) Relationship between skin collagen and bone changes during aging. Maturitas 18(3):199–206PubMedCrossRef

50.

Fujii K, Tanzer ML (1974) Age-related changes in the reducible crosslinks of human tendon collagen. FEBS Lett 43(3):300–302PubMedCrossRef

51.

Wagh PV, Leverich AP, Sun CN, White HJ, Read RC (1974) Direct inguinal herniation in men: a disease of collagen. J Surg Res 17(6):425–433PubMedCrossRef

52.

Ashcroft GS, Horan MA, Ferguson MW (1997) Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model. J Invest Dermatol 108(4):430–437PubMedCrossRef

53.

Lenhardt R, Hopf HW, Marker E, Akca O, Kurz A, Scheuenstuhl H, Sessler DI (2000) Perioperative collagen deposition in elderly and young men and women. Arch Surg 135(1):71–74PubMedCrossRef

54.

Jorgensen LN, Sorensen LT, Kallehave F, Vange J, Gottrup F (2002) Premenopausal women deposit more collagen than men during healing of an experimental wound. Surgery 131(3):338–343PubMedCrossRef

55.

Gniadecki R, Wyrwas B, Kabala A, Matecka J (1996) Impairment of granulation tissue formation after menopause. J Endocrinol Invest 19(4):215–218PubMed

56.

Affinito P, Palomba S, Sorrentino C, Di Carlo C, Bifulco G, Arienzo MP, Nappi C (1999) Effects of postmenopausal hypoestrogenism on skin collagen. Maturitas 33(3):239–247PubMedCrossRef

57.

Ashcroft GS, Greenwell-Wild T, Horan MA, Wahl SM, Ferguson MW (1999) Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response. Am J Pathol 155(4):1137–1146PubMed

58.

Tarlton JF, Vickery CJ, Leaper DJ, Bailey AJ (1997) Postsurgical wound progression monitored by temporal changes in the expression of matrix metalloproteinase-9. Br J Dermatol 137(4):506–516PubMedCrossRef

59.

Ashcroft GS, Horan MA, Herrick SE, Tarnuzzer RW, Schultz GS, Ferguson MW (1997) Age-related differences in the temporal and spatial regulation of matrix metalloproteinases (MMPs) in normal skin and acute cutaneous wounds of healthy humans. Cell Tissue Res 290(3):581–591PubMedCrossRef

60.

Ashcroft GS, Herrick SE, Tarnuzzer RW, Horan MA, Schultz GS, Ferguson MW (1997) Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and -2 proteins and mRNA. J Pathol 183(2):169–176PubMedCrossRef

Title: Effect of lifestyle, gender and age on collagen formation and degradation
Author: Lars Tue Sørensen
Publication date: 01-12-2006
Publisher: Springer-Verlag
Published in: Hernia / Issue 6/2006
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI: https://doi.org/10.1007/s10029-006-0143-x

2024 ASCO Annual Meeting

Springer Medicine

Effect of lifestyle, gender and age on collagen formation and degradation

Abstract

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 6/2006

Laparoscopy and collagen metabolism

Collagen metabolism and recurrent hiatal hernia: cause and effect?

Perforated appendix and periappendicular abscess within an inguinal hernia

Are collagens the culprits in the development of incisional and inguinal hernia disease?

Radiation responses in skin and connective tissues: effect on wound healing and surgical outcome

Collagenase and surgical disease