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Published in: Hernia 6/2006

01-12-2006 | Review

Laparoscopy and collagen metabolism

Authors: R. Rosch, K. Junge, M. Binnebösel, P. Bertram, U. Klinge, V. Schumpelick

Published in: Hernia | Issue 6/2006

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Abstract

The collagens represent a vital component within the wound healing process and physiological scar formation. Therefore, analysing the influence of new operative procedures on collagen metabolism is of great surgical interest. As the endoscopic technique has, nowadays, become routinely applied for diverse abdominal diseases worldwide, we present a review of literature facing its impact on collagen biology.
Literature
1.
2.
go back to reference Vaalamo M, Mattila L, Johansson N, Kariniemi AL, Karjalainen-Lindsberg ML, Kahari VM, Saarialho-Kere U (1997) Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds. J Invest Dermatol 109:96–101PubMedCrossRef Vaalamo M, Mattila L, Johansson N, Kariniemi AL, Karjalainen-Lindsberg ML, Kahari VM, Saarialho-Kere U (1997) Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds. J Invest Dermatol 109:96–101PubMedCrossRef
3.
go back to reference Portera CA, Love EJ, Memore L, Zhang L, Muller A, Browder W, Williams DL (1997) Effect of macrophage stimulation on collagen biosynthesis in the healing wound. Am Surg 63:125–131PubMed Portera CA, Love EJ, Memore L, Zhang L, Muller A, Browder W, Williams DL (1997) Effect of macrophage stimulation on collagen biosynthesis in the healing wound. Am Surg 63:125–131PubMed
4.
go back to reference Browder W, Williams D, Lucore P, Pretus H, Jones E, McNamee R (1988) Effect of enhanced macrophage function on early wound healing. Surgery 104:224–230PubMed Browder W, Williams D, Lucore P, Pretus H, Jones E, McNamee R (1988) Effect of enhanced macrophage function on early wound healing. Surgery 104:224–230PubMed
5.
go back to reference Stadelmann WK, Digenis AG, Tobin GR (1998) Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 176:26S–38SPubMedCrossRef Stadelmann WK, Digenis AG, Tobin GR (1998) Physiology and healing dynamics of chronic cutaneous wounds. Am J Surg 176:26S–38SPubMedCrossRef
6.
go back to reference Wiedemann H, Chung E, Fujii T, Miller EJ, Kuhn K (1975) Comparative electron-microscope studies on type-III and type-I collagens. Eur J Biochem 51:363–368PubMedCrossRef Wiedemann H, Chung E, Fujii T, Miller EJ, Kuhn K (1975) Comparative electron-microscope studies on type-III and type-I collagens. Eur J Biochem 51:363–368PubMedCrossRef
7.
go back to reference Stumpf M, Klinge U, Wilms A, Zabrocki R, Rosch R, Junge K, Krones C, Schumpelick V (2005) Changes of the extracellular matrix as a risk factor for anastomotic leakage after large bowel surgery. Surgery 137:229–234PubMedCrossRef Stumpf M, Klinge U, Wilms A, Zabrocki R, Rosch R, Junge K, Krones C, Schumpelick V (2005) Changes of the extracellular matrix as a risk factor for anastomotic leakage after large bowel surgery. Surgery 137:229–234PubMedCrossRef
8.
go back to reference Junge K, Klinge U, Rosch R, Mertens PR, Kirch J, Klosterhalfen B, Lynen P, Schumpelick V (2004) Decreased collagen type I/III ratio in patients with recurring hernia after implantation of alloplastic prostheses. Langenbecks Arch Surg 389:17–22PubMedCrossRef Junge K, Klinge U, Rosch R, Mertens PR, Kirch J, Klosterhalfen B, Lynen P, Schumpelick V (2004) Decreased collagen type I/III ratio in patients with recurring hernia after implantation of alloplastic prostheses. Langenbecks Arch Surg 389:17–22PubMedCrossRef
9.
go back to reference Jacobi CA, Wenger FA, Ordemann J, Gutt C, Sabat R, Muller JM (1998) Experimental study of the effect of intra-abdominal pressure during laparoscopy on tumour growth and port site metastasis. Br J Surg 85:1419–1422PubMedCrossRef Jacobi CA, Wenger FA, Ordemann J, Gutt C, Sabat R, Muller JM (1998) Experimental study of the effect of intra-abdominal pressure during laparoscopy on tumour growth and port site metastasis. Br J Surg 85:1419–1422PubMedCrossRef
10.
go back to reference Holthausen UH, Nagelschmidt M, Troidl H (1999) CO2 pneumoperitoneum: what we know and what we need to know. World J Surg 23:794–800PubMedCrossRef Holthausen UH, Nagelschmidt M, Troidl H (1999) CO2 pneumoperitoneum: what we know and what we need to know. World J Surg 23:794–800PubMedCrossRef
11.
go back to reference Kuntz C, Wunsch A, Rosch R, Autschbach F, Windeler J, Herfarth C (2000) Short- and long-term results after laparoscopic versus conventional colon resection in a tumor-bearing small animal model. Surg Endosc 14:561–567PubMedCrossRef Kuntz C, Wunsch A, Rosch R, Autschbach F, Windeler J, Herfarth C (2000) Short- and long-term results after laparoscopic versus conventional colon resection in a tumor-bearing small animal model. Surg Endosc 14:561–567PubMedCrossRef
12.
go back to reference Ishizaki Y, Bandai Y, Shimomura K, Abe H, Ohtomo Y, Idezuki Y (1993) Changes in splanchnic blood flow and cardiovascular effects following peritoneal insufflation of carbon dioxide. Surg Endosc 7:420–423PubMedCrossRef Ishizaki Y, Bandai Y, Shimomura K, Abe H, Ohtomo Y, Idezuki Y (1993) Changes in splanchnic blood flow and cardiovascular effects following peritoneal insufflation of carbon dioxide. Surg Endosc 7:420–423PubMedCrossRef
13.
go back to reference Rademaker BM, Bannenberg JJ, Kalkman CJ, Meyer DW (1995) Effects of pneumoperitoneum with helium on hemodynamics and oxygen transport: a comparison with carbon dioxide. J Laparoendosc Surg 5:15–20PubMed Rademaker BM, Bannenberg JJ, Kalkman CJ, Meyer DW (1995) Effects of pneumoperitoneum with helium on hemodynamics and oxygen transport: a comparison with carbon dioxide. J Laparoendosc Surg 5:15–20PubMed
14.
go back to reference Berguer R, Gutt CN (1994) Laparoscopic colon surgery in a rat model. A preliminary report. Surg Endosc 8:1195–1197PubMedCrossRef Berguer R, Gutt CN (1994) Laparoscopic colon surgery in a rat model. A preliminary report. Surg Endosc 8:1195–1197PubMedCrossRef
15.
go back to reference Sietses C, Wiezer MJ, Eijsbouts QA, Beelen RH, van Leeuwen PA, von Blomberg BM, Meijer S, Cuesta MA (1999) A prospective randomized study of the systemic immune response after laparoscopic and conventional Nissen fundoplication. Surgery 126:5–9PubMedCrossRef Sietses C, Wiezer MJ, Eijsbouts QA, Beelen RH, van Leeuwen PA, von Blomberg BM, Meijer S, Cuesta MA (1999) A prospective randomized study of the systemic immune response after laparoscopic and conventional Nissen fundoplication. Surgery 126:5–9PubMedCrossRef
16.
go back to reference Gutt CN, Kuntz C, Schmandra T, Wunsch A, Heinz P, Bouvy N, Bessler M, Sanger P, Bonjer J, Allendorf J, Jacobi CA, Whelan R (1998) Metabolism and immunology in laparoscopy. First workshop on experimental laparoscopic surgery, Frankfurt, 1997. Surg Endosc 12:1096–1098PubMedCrossRef Gutt CN, Kuntz C, Schmandra T, Wunsch A, Heinz P, Bouvy N, Bessler M, Sanger P, Bonjer J, Allendorf J, Jacobi CA, Whelan R (1998) Metabolism and immunology in laparoscopy. First workshop on experimental laparoscopic surgery, Frankfurt, 1997. Surg Endosc 12:1096–1098PubMedCrossRef
17.
go back to reference Attard JA, Raval MJ, Martin GR, Kolb J, Afrouzian M, Buie WD, Sigalet DL (2005) The effects of systemic hypoxia on colon anastomotic healing: an animal model. Dis Colon Rectum 48:1460–1470PubMedCrossRef Attard JA, Raval MJ, Martin GR, Kolb J, Afrouzian M, Buie WD, Sigalet DL (2005) The effects of systemic hypoxia on colon anastomotic healing: an animal model. Dis Colon Rectum 48:1460–1470PubMedCrossRef
18.
go back to reference Whitney JD (1990) The influence of tissue oxygen and perfusion on wound healing. AACN Clin Issues Crit Care Nurs 1:578–584PubMed Whitney JD (1990) The influence of tissue oxygen and perfusion on wound healing. AACN Clin Issues Crit Care Nurs 1:578–584PubMed
19.
go back to reference Jonsson K, Jensen JA, Goodson WH III, Scheuenstuhl H, West J, Hopf HW, Hunt TK (1991) Tissue oxygenation, anemia, and perfusion in relation to wound healing in surgical patients. Ann Surg 214:605–613PubMedCrossRef Jonsson K, Jensen JA, Goodson WH III, Scheuenstuhl H, West J, Hopf HW, Hunt TK (1991) Tissue oxygenation, anemia, and perfusion in relation to wound healing in surgical patients. Ann Surg 214:605–613PubMedCrossRef
20.
go back to reference Bongard F, Pianim N, Dubecz S, Klein SR (1995) Adverse consequences of increased intra-abdominal pressure on bowel tissue oxygen. J Trauma 39:519–524PubMedCrossRef Bongard F, Pianim N, Dubecz S, Klein SR (1995) Adverse consequences of increased intra-abdominal pressure on bowel tissue oxygen. J Trauma 39:519–524PubMedCrossRef
21.
go back to reference Diebel LN, Wilson RF, Dulchavsky SA, Saxe J (1992) Effect of increased intra-abdominal pressure on hepatic arterial, portal venous, and hepatic microcirculatory blood flow. J Trauma 33:279–282PubMedCrossRef Diebel LN, Wilson RF, Dulchavsky SA, Saxe J (1992) Effect of increased intra-abdominal pressure on hepatic arterial, portal venous, and hepatic microcirculatory blood flow. J Trauma 33:279–282PubMedCrossRef
22.
go back to reference Thomson IA, Fitch W, Hughes RL, Campbell D (1983) Effect of increased concentrations of carbon dioxide during halothane anaesthesia on liver blood flow and hepatic oxygen consumption. Br J Anaesth 55:1231–1237PubMedCrossRef Thomson IA, Fitch W, Hughes RL, Campbell D (1983) Effect of increased concentrations of carbon dioxide during halothane anaesthesia on liver blood flow and hepatic oxygen consumption. Br J Anaesth 55:1231–1237PubMedCrossRef
23.
go back to reference Jackson PG, Evans SR (2000) Intraperitoneal macrophages and tumor immunity: a review. J Surg Oncol 75:146–154PubMedCrossRef Jackson PG, Evans SR (2000) Intraperitoneal macrophages and tumor immunity: a review. J Surg Oncol 75:146–154PubMedCrossRef
24.
go back to reference Gutt CN, Heinz P, Kaps W, Paolucci V (1997) The phagocytosis activity during conventional and laparoscopic operations in the rat. A preliminary study. Surg Endosc 11:899–901PubMedCrossRef Gutt CN, Heinz P, Kaps W, Paolucci V (1997) The phagocytosis activity during conventional and laparoscopic operations in the rat. A preliminary study. Surg Endosc 11:899–901PubMedCrossRef
25.
go back to reference Chekan EG, Nataraj C, Clary EM, Hayward TZ, Brody FJ, Stamat JC, Fina MC, Eubanks WS, Westcott CJ (1999) Intraperitoneal immunity and pneumoperitoneum. Surg Endosc 13:1135–1138PubMedCrossRef Chekan EG, Nataraj C, Clary EM, Hayward TZ, Brody FJ, Stamat JC, Fina MC, Eubanks WS, Westcott CJ (1999) Intraperitoneal immunity and pneumoperitoneum. Surg Endosc 13:1135–1138PubMedCrossRef
26.
go back to reference Jacobi CA, Ordemann J, Halle E, Volk HD, Muller JM (1999) Impact of laparoscopy with carbon dioxide versus helium on local and systemic inflammation in an animal model of peritonitis. J Laparoendosc Adv Surg Tech A 9:305–312PubMedCrossRef Jacobi CA, Ordemann J, Halle E, Volk HD, Muller JM (1999) Impact of laparoscopy with carbon dioxide versus helium on local and systemic inflammation in an animal model of peritonitis. J Laparoendosc Adv Surg Tech A 9:305–312PubMedCrossRef
27.
go back to reference Kuntz C, Wunsch A, Bodeker C, Bay F, Rosch R, Windeler J, Herfarth C (2000) Effect of pressure and gas type on intraabdominal, subcutaneous, and blood pH in laparoscopy. Surg Endosc 14:367–371PubMedCrossRef Kuntz C, Wunsch A, Bodeker C, Bay F, Rosch R, Windeler J, Herfarth C (2000) Effect of pressure and gas type on intraabdominal, subcutaneous, and blood pH in laparoscopy. Surg Endosc 14:367–371PubMedCrossRef
28.
go back to reference Neuberger TJ, Andrus CH, Wittgen CM, Wade TP, Kaminski DL (1996) Prospective comparison of helium versus carbon dioxide pneumoperitoneum. Gastrointest Endosc 43:38–41PubMedCrossRef Neuberger TJ, Andrus CH, Wittgen CM, Wade TP, Kaminski DL (1996) Prospective comparison of helium versus carbon dioxide pneumoperitoneum. Gastrointest Endosc 43:38–41PubMedCrossRef
29.
go back to reference Naude GP, Bongard FS (1995) Helium insufflation in laparoscopic surgery. Endosc Surg Allied Technol 3:183–186PubMed Naude GP, Bongard FS (1995) Helium insufflation in laparoscopic surgery. Endosc Surg Allied Technol 3:183–186PubMed
30.
go back to reference Wood GC, Keech MK (1960) The formation of fibrils from collagen solutions. 1. The effect of experimental conditions: kinetic and electron-microscope studies. Biochem J 75:588–598PubMed Wood GC, Keech MK (1960) The formation of fibrils from collagen solutions. 1. The effect of experimental conditions: kinetic and electron-microscope studies. Biochem J 75:588–598PubMed
31.
go back to reference Vanamee P, Porter KR (1951) Observations with the electron microscope on the solvation and reconstitution of collagen. J Exp Med 94:255–266PubMedCrossRef Vanamee P, Porter KR (1951) Observations with the electron microscope on the solvation and reconstitution of collagen. J Exp Med 94:255–266PubMedCrossRef
32.
go back to reference Nigra TP, Martin GR, Eagle H (1973) The effect of environmental pH on collagen synthesis by cultured cells. Biochem Biophys Res Commun 53:272–281PubMedCrossRef Nigra TP, Martin GR, Eagle H (1973) The effect of environmental pH on collagen synthesis by cultured cells. Biochem Biophys Res Commun 53:272–281PubMedCrossRef
33.
go back to reference Bard JB, Hulmes DJ, Purdom IF, Ross AS (1993) Chick corneal development in vitro: diverse effects of pH on collagen assembly. J Cell Sci 105(Pt 4):1045–1055PubMed Bard JB, Hulmes DJ, Purdom IF, Ross AS (1993) Chick corneal development in vitro: diverse effects of pH on collagen assembly. J Cell Sci 105(Pt 4):1045–1055PubMed
34.
go back to reference Eljaafari A, Duperrier K, Mazet S, Bardin C, Bernaud J, Durand B, Gebuhrer L, Betuel H, Rigal D (1998) Generation of stable monocyte-derived dendritic cells in the presence of high concentrations of homologous or autologous serum: influence of extra-cellular pH. Hum Immunol 59:625–634PubMedCrossRef Eljaafari A, Duperrier K, Mazet S, Bardin C, Bernaud J, Durand B, Gebuhrer L, Betuel H, Rigal D (1998) Generation of stable monocyte-derived dendritic cells in the presence of high concentrations of homologous or autologous serum: influence of extra-cellular pH. Hum Immunol 59:625–634PubMedCrossRef
35.
go back to reference Wildbrett P, Oh A, Naundorf D, Volk T, Jacobi CA (2003) Impact of laparoscopic gases on peritoneal microenvironment and essential parameters of cell function. Surg Endosc 17:78–82PubMedCrossRef Wildbrett P, Oh A, Naundorf D, Volk T, Jacobi CA (2003) Impact of laparoscopic gases on peritoneal microenvironment and essential parameters of cell function. Surg Endosc 17:78–82PubMedCrossRef
36.
go back to reference Paraskeva PA, Ridgway PF, Jones T, Smith A, Peck DH, Darzi AW (2005) Laparoscopic environmental changes during surgery enhance the invasive potential of tumours. Tumour Biol 26:94–102PubMedCrossRef Paraskeva PA, Ridgway PF, Jones T, Smith A, Peck DH, Darzi AW (2005) Laparoscopic environmental changes during surgery enhance the invasive potential of tumours. Tumour Biol 26:94–102PubMedCrossRef
37.
go back to reference Syk I, Mirastschijski U, Jeppsson BW, Agren MS (2003) Experimental colonic obstruction increases collagen degradation by matrix metalloproteinases in the bowel wall. Dis Colon Rectum 46:1251–1259PubMedCrossRef Syk I, Mirastschijski U, Jeppsson BW, Agren MS (2003) Experimental colonic obstruction increases collagen degradation by matrix metalloproteinases in the bowel wall. Dis Colon Rectum 46:1251–1259PubMedCrossRef
38.
go back to reference Onodera H, Ikeuchi D, Nagayama S, Imamura M (2004) Weakness of anastomotic site in diabetic rats is caused by changes in the integrity of newly formed collagen. Dig Surg 21:146–151PubMedCrossRef Onodera H, Ikeuchi D, Nagayama S, Imamura M (2004) Weakness of anastomotic site in diabetic rats is caused by changes in the integrity of newly formed collagen. Dig Surg 21:146–151PubMedCrossRef
39.
go back to reference Kologlu M, Sayek I, Kologlu LB, Eng C, Onat D (1999) Effect of persistently elevated intraabdominal pressure on healing of colonic anastomoses. Am J Surg 178:293–297PubMedCrossRef Kologlu M, Sayek I, Kologlu LB, Eng C, Onat D (1999) Effect of persistently elevated intraabdominal pressure on healing of colonic anastomoses. Am J Surg 178:293–297PubMedCrossRef
40.
go back to reference Polat C, Arikan Y, Vatansev C, Akbulut G, Yilmaz S, Dilek FH, Gokce O (2002) The effects of increased intraabdominal pressure on colonic anastomoses. Surg Endosc 16:1314–1319PubMedCrossRef Polat C, Arikan Y, Vatansev C, Akbulut G, Yilmaz S, Dilek FH, Gokce O (2002) The effects of increased intraabdominal pressure on colonic anastomoses. Surg Endosc 16:1314–1319PubMedCrossRef
41.
go back to reference Rosch R, Stumpf M, Junge K, Ardic D, Ulmer F, Schumpelick V (2004) Impact of pressure and gas type on anastomotic wound healing in rats. Langenbecks Arch Surg 389:261–266PubMedCrossRef Rosch R, Stumpf M, Junge K, Ardic D, Ulmer F, Schumpelick V (2004) Impact of pressure and gas type on anastomotic wound healing in rats. Langenbecks Arch Surg 389:261–266PubMedCrossRef
42.
go back to reference Rosch R, Stumpf M, Junge K, Drinjakovic D, Schachtrupp A, Afify M, Schumpelick V (2005) Influence of pneumoperitoneum on small bowel anastomoses: a histological analysis in the rat model. J Invest Surg 18:63–69PubMedCrossRef Rosch R, Stumpf M, Junge K, Drinjakovic D, Schachtrupp A, Afify M, Schumpelick V (2005) Influence of pneumoperitoneum on small bowel anastomoses: a histological analysis in the rat model. J Invest Surg 18:63–69PubMedCrossRef
43.
go back to reference Murray JA, Cornwell EE III, Velmahos GC, Rivkind AI, Hedman T, Abrahams JH, Katkhouda N, Berne TV, Demetriades D (2001) Healing of traumatic diaphragm injuries: comparison of laparoscopic versus open techniques in an animal model. J Surg Res 100:189–191PubMedCrossRef Murray JA, Cornwell EE III, Velmahos GC, Rivkind AI, Hedman T, Abrahams JH, Katkhouda N, Berne TV, Demetriades D (2001) Healing of traumatic diaphragm injuries: comparison of laparoscopic versus open techniques in an animal model. J Surg Res 100:189–191PubMedCrossRef
44.
go back to reference Kockerling F, Rose J, Schneider C, Scheidbach H, Scheuerlein H, Reymond MA, Reck T, Konradt J, Bruch HP, Zornig C, Barlehner E, Kuthe A, Szinicz G, Richter HA, Hohenberger W (1999) Laparoscopic colorectal anastomosis: risk of postoperative leakage. Results of a multicenter study. Laparoscopic Colorectal Surgery Study Group (LCSSG). Surg Endosc 13:639–644PubMedCrossRef Kockerling F, Rose J, Schneider C, Scheidbach H, Scheuerlein H, Reymond MA, Reck T, Konradt J, Bruch HP, Zornig C, Barlehner E, Kuthe A, Szinicz G, Richter HA, Hohenberger W (1999) Laparoscopic colorectal anastomosis: risk of postoperative leakage. Results of a multicenter study. Laparoscopic Colorectal Surgery Study Group (LCSSG). Surg Endosc 13:639–644PubMedCrossRef
45.
go back to reference Hartley JE, Mehigan BJ, Qureshi AE, Duthie GS, Lee PW, Monson JR (2001) Total mesorectal excision: assessment of the laparoscopic approach. Dis Colon Rectum 44:315–321PubMedCrossRef Hartley JE, Mehigan BJ, Qureshi AE, Duthie GS, Lee PW, Monson JR (2001) Total mesorectal excision: assessment of the laparoscopic approach. Dis Colon Rectum 44:315–321PubMedCrossRef
46.
go back to reference Yamamoto S, Watanabe M, Hasegawa H, Kitajima M (2002) Prospective evaluation of laparoscopic surgery for rectosigmoidal and rectal carcinoma. Dis Colon Rectum 45: 1648–1654PubMedCrossRef Yamamoto S, Watanabe M, Hasegawa H, Kitajima M (2002) Prospective evaluation of laparoscopic surgery for rectosigmoidal and rectal carcinoma. Dis Colon Rectum 45: 1648–1654PubMedCrossRef
47.
go back to reference Willis S, Ulmer F, Fell T, Butz N, Tittel A, Schumpelick V (2005) Laparoscopic colectomy versus open colectomy for sigmoid diverticular disease in routine surgery. Viszeralchirurgie 40:27–32CrossRef Willis S, Ulmer F, Fell T, Butz N, Tittel A, Schumpelick V (2005) Laparoscopic colectomy versus open colectomy for sigmoid diverticular disease in routine surgery. Viszeralchirurgie 40:27–32CrossRef
48.
go back to reference Thaler K, Dinnewitzer A, Mascha E, Arrigain S, Weiss EG, Nogueras JJ, Wexner SD (2003) Long-term outcome and health-related quality of life after laparoscopic and open colectomy for benign disease. Surg Endosc 17:1404–1408PubMedCrossRef Thaler K, Dinnewitzer A, Mascha E, Arrigain S, Weiss EG, Nogueras JJ, Wexner SD (2003) Long-term outcome and health-related quality of life after laparoscopic and open colectomy for benign disease. Surg Endosc 17:1404–1408PubMedCrossRef
49.
go back to reference Agalar F, Hamaloglu E, Daphan C, Tarim A, Onur R, Renda N, Sayek I (2000) Effects of CO2 insufflation and laparotomy on wound healing in mice. Aust N Z J Surg 70:739–742PubMedCrossRef Agalar F, Hamaloglu E, Daphan C, Tarim A, Onur R, Renda N, Sayek I (2000) Effects of CO2 insufflation and laparotomy on wound healing in mice. Aust N Z J Surg 70:739–742PubMedCrossRef
50.
go back to reference Winslow ER, Fleshman JW, Birnbaum EH, Brunt LM (2002) Wound complications of laparoscopic versus open colectomy. Surg Endosc 16:1420–1425PubMedCrossRef Winslow ER, Fleshman JW, Birnbaum EH, Brunt LM (2002) Wound complications of laparoscopic versus open colectomy. Surg Endosc 16:1420–1425PubMedCrossRef
51.
go back to reference Rosch R, Junge K, Binnebösel M, Mirgarth N, Klinge U, Schumpelick V (2006) Improved abdominal wall wound healing by helium pneumoperitoneum. Surg Endosc (in press) Rosch R, Junge K, Binnebösel M, Mirgarth N, Klinge U, Schumpelick V (2006) Improved abdominal wall wound healing by helium pneumoperitoneum. Surg Endosc (in press)
Metadata
Title
Laparoscopy and collagen metabolism
Authors
R. Rosch
K. Junge
M. Binnebösel
P. Bertram
U. Klinge
V. Schumpelick
Publication date
01-12-2006
Publisher
Springer-Verlag
Published in
Hernia / Issue 6/2006
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI
https://doi.org/10.1007/s10029-006-0151-x

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