Skip to main content
Top
Published in: Oral and Maxillofacial Surgery 4/2009

01-12-2009 | Case Report

Hemangioma of the mandible: case report with special emphasis on bone degradation

Authors: Torsten Hansen, Martin Kunkel, Detlef Katenkamp, Sami Eletr, Wilfried Wagner

Published in: Oral and Maxillofacial Surgery | Issue 4/2009

Login to get access

Abstract

Purpose

Intraosseous hemangioma of the mandible is a rare tumor. In this report, we present a case with a particularly prominent osteolysis and discuss the histological features of bone degradation.

Materials and methods

We describe a 64-year-old female patient with a cystic tumor mass of the mandible leading to pathologic bone fracture. X-ray analysis was suggestive for aneurysmatic bone cyst. A segment resection was performed.

Results

The histological examination revealed a mesenchymal tumor with numerous capillaries and dilated vessels immunohistochemically being positive for CD31, but not for D2-40. In addition, there was a remarkable increase of osteoclasts that sometimes exhibited Howship’s lacunae. The tumor was diagnosed as intraosseous hemangioma with prominent bone degradation.

Conclusions

Based on our histological findings, it should be further investigated whether there could be an association between angiogenesis and osteoclastogenesis as a central pathway leading to bone destruction in the case of intraosseous hemangiomas.
Literature
1.
go back to reference Adler CP, Wold L (2002) Hemangioma and related lesions. In: Fletcher CDM, Unni K, Mertens F (eds) Pathology and genetics of tumors of soft tissue and bone. IARC, Lyon, pp 320–321 Adler CP, Wold L (2002) Hemangioma and related lesions. In: Fletcher CDM, Unni K, Mertens F (eds) Pathology and genetics of tumors of soft tissue and bone. IARC, Lyon, pp 320–321
2.
go back to reference Barnes L (1985) Solitary hemangioma of bone. In: Barnes L (ed) Surgical pathology of the head and neck, vol. 1. Dekker, New York, pp 932–936 Barnes L (1985) Solitary hemangioma of bone. In: Barnes L (ed) Surgical pathology of the head and neck, vol. 1. Dekker, New York, pp 932–936
3.
go back to reference Heckl S, Aschoff A, Kunze S (2002) Cavernomas of the skull: review of the literature 1975–2002. Neurosurg Rev 25:56–62CrossRefPubMed Heckl S, Aschoff A, Kunze S (2002) Cavernomas of the skull: review of the literature 1975–2002. Neurosurg Rev 25:56–62CrossRefPubMed
4.
go back to reference Özdemir R, Alagoz S, Uysal AC et al (2002) Intraosseous hemangioma of the mandible: a case report and review of the literature. J Craniofac Surg 13:38–43CrossRefPubMed Özdemir R, Alagoz S, Uysal AC et al (2002) Intraosseous hemangioma of the mandible: a case report and review of the literature. J Craniofac Surg 13:38–43CrossRefPubMed
5.
go back to reference Perugini M, Renzi G, Gasparini G et al (2004) Intraosseous hemangioma of the maxillofacial district: clinical analysis and surgical treatment in 10 consecutive patients. J Craniofac Surg 15:980–985CrossRefPubMed Perugini M, Renzi G, Gasparini G et al (2004) Intraosseous hemangioma of the maxillofacial district: clinical analysis and surgical treatment in 10 consecutive patients. J Craniofac Surg 15:980–985CrossRefPubMed
6.
go back to reference Giaoui L, Princ G, Chiras J et al (2003) Treatment of vascular malformations of the mandible: a description of 12 cases. Int J Oral Maxillofac Surg 32:312–316CrossRef Giaoui L, Princ G, Chiras J et al (2003) Treatment of vascular malformations of the mandible: a description of 12 cases. Int J Oral Maxillofac Surg 32:312–316CrossRef
7.
go back to reference Gomez Oliveira G, Garcia-Rozado A, Luaces Rey R (2008) Intraosseous mandibular hemangioma. A case report and review of the literature. Med Oral Patol Oral Cir Bucal 13:E496–E498PubMed Gomez Oliveira G, Garcia-Rozado A, Luaces Rey R (2008) Intraosseous mandibular hemangioma. A case report and review of the literature. Med Oral Patol Oral Cir Bucal 13:E496–E498PubMed
8.
go back to reference Adegboyega PA, Qiu S (2005) Hemangioma versus vascular malformation. Presence of nerve bundle is a diagnostic clue for vascular malformation. Arch Pathol Lab Med 129:772–775PubMed Adegboyega PA, Qiu S (2005) Hemangioma versus vascular malformation. Presence of nerve bundle is a diagnostic clue for vascular malformation. Arch Pathol Lab Med 129:772–775PubMed
9.
go back to reference Bataille R (1995) The mechanisms of bone lesions in plasmocytomas. Stem Cells 13(Suppl 2):40–47PubMed Bataille R (1995) The mechanisms of bone lesions in plasmocytomas. Stem Cells 13(Suppl 2):40–47PubMed
10.
go back to reference Kataoka M, Torisu T, Tsumura H et al (2000) Role of multinuclear cells in granulation tissue in osteomyelitis: immunohistochemistry in 66 patients. Acta Orthop Scand 71:414–418CrossRefPubMed Kataoka M, Torisu T, Tsumura H et al (2000) Role of multinuclear cells in granulation tissue in osteomyelitis: immunohistochemistry in 66 patients. Acta Orthop Scand 71:414–418CrossRefPubMed
11.
go back to reference Hansen T, Kirkpatrick CJ, Walter C et al (2006) Increased numbers of osteoclasts expressing cysteine proteinase cathepsin K in patients with infected osteoradionecrosis and bisphosphonate-associated osteonecrosis—a paradoxical observation? Virchows Arch 449:448–454CrossRefPubMed Hansen T, Kirkpatrick CJ, Walter C et al (2006) Increased numbers of osteoclasts expressing cysteine proteinase cathepsin K in patients with infected osteoradionecrosis and bisphosphonate-associated osteonecrosis—a paradoxical observation? Virchows Arch 449:448–454CrossRefPubMed
12.
go back to reference Lamovec J, Bracko M (1996) Epithelioid hemangioma of small tubular bones: a report of three cases, two of them associated with pregnancy. Mod Pathol 9:821–827PubMed Lamovec J, Bracko M (1996) Epithelioid hemangioma of small tubular bones: a report of three cases, two of them associated with pregnancy. Mod Pathol 9:821–827PubMed
13.
go back to reference Möller G, Priemel M, Amling M et al (1999) The Gorham–Stout syndrome (Gorham’s massive osteolysis). J Bone Joint Surg [Br] 81-B:501–506CrossRef Möller G, Priemel M, Amling M et al (1999) The Gorham–Stout syndrome (Gorham’s massive osteolysis). J Bone Joint Surg [Br] 81-B:501–506CrossRef
14.
go back to reference Colucci S, Taraboletti G, Primo L et al (2006) Gorham—Stout syndrome: a monocyte-mediated cytokine propelled disease. J Bone Miner Res 21:207–218CrossRefPubMed Colucci S, Taraboletti G, Primo L et al (2006) Gorham—Stout syndrome: a monocyte-mediated cytokine propelled disease. J Bone Miner Res 21:207–218CrossRefPubMed
15.
go back to reference Cackowski FC, Roodman GD (2007) Perspective on the osteoclast: an angiogenic cell? Ann N Y Acad Sci 1117:12–25CrossRefPubMed Cackowski FC, Roodman GD (2007) Perspective on the osteoclast: an angiogenic cell? Ann N Y Acad Sci 1117:12–25CrossRefPubMed
Metadata
Title
Hemangioma of the mandible: case report with special emphasis on bone degradation
Authors
Torsten Hansen
Martin Kunkel
Detlef Katenkamp
Sami Eletr
Wilfried Wagner
Publication date
01-12-2009
Publisher
Springer-Verlag
Published in
Oral and Maxillofacial Surgery / Issue 4/2009
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI
https://doi.org/10.1007/s10006-009-0172-6

Other articles of this Issue 4/2009

Oral and Maxillofacial Surgery 4/2009 Go to the issue