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Published in: Clinical Oral Investigations 7/2015

01-09-2015 | Original Article

Clinical evaluation of the efficacy of one self-adhesive composite in dental hypersensitivity

Authors: R. Pinna, A. Bortone, G. Sotgiu, S. Dore, P. Usai, E. Milia

Published in: Clinical Oral Investigations | Issue 7/2015

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Abstract

Objectives

The aim of the present study was to investigate the clinical effectiveness over 12 weeks of Vertise Flow, a self-adhering composite, in dental hypersensitivity (DH).

Material and methods

The study was conducted as a split-mouth randomized clinical trial. Vertise Flow™ was compared to the following: (1) Universal Dentine Sealant, (2) Clearfil Protect Bond, and (3) Flor-Opal® Varnish. A total of 46 patients with 116 hypersensitive teeth were studied. Pain experience was generated by a cold stimulus and assessed using the visual analog scale (VAS) of pain. The response was recorded before the application of the materials (pre-1), immediately after (post-1), at 1- (post-2), 2- (post-3), and 12-week controls (post-4). Statistical differences in VAS were performed using the Kruskal–Wallis analysis at the different time-points (P < 0.05), adjusting statistical significances for multiple comparisons (Bonferroni correction).

Results

All the materials showed any statistically significant differences at the baseline. After the application of each material, a VAS decrease was demonstrated at every post-control. VF showed significant hypersensitivity reduction in post-1. Statistically significant relief was also observed in post-2 while no significant differences were detected in post-3 and post-4.

Conclusions

After 12-week controls, there was no statistically significant hypersensitivity reduction using VF in respect to the other materials. On the other hand, any significant differences were detected in the decrease of the VAS irrespective of the desensitizing agent employed at the 12-week controls.

Clinical relevance

The significant increase in VAS scores within the 12-weeks of environment suggested there is instability of VF when used as desensitizing agent.
Literature
1.
go back to reference Splieth CH, Tachou A (2013) Epidemiology of dentin hypersensitivity. Clin Oral Investig 17(Suppl 1):S3–8.1CrossRefPubMed Splieth CH, Tachou A (2013) Epidemiology of dentin hypersensitivity. Clin Oral Investig 17(Suppl 1):S3–8.1CrossRefPubMed
3.
go back to reference Brännström M, Linden LA, Johnson G (1968) Movement of dentinal and pulpal fluid caused by clinical procedures. J Dent Res 47:679–682CrossRefPubMed Brännström M, Linden LA, Johnson G (1968) Movement of dentinal and pulpal fluid caused by clinical procedures. J Dent Res 47:679–682CrossRefPubMed
4.
go back to reference Pashley DH (1986) Dentine permeability, dentine sensitivity and treatment though tubule occlusion. J Endod 12:465–474CrossRefPubMed Pashley DH (1986) Dentine permeability, dentine sensitivity and treatment though tubule occlusion. J Endod 12:465–474CrossRefPubMed
5.
go back to reference Van Loveren C (2013) Exposed cervical dentin and dentin hypersensitivity summary of the discussion and recommendations. Clin Oral Investig 17(Suppl 1):S73–S76CrossRefPubMed Van Loveren C (2013) Exposed cervical dentin and dentin hypersensitivity summary of the discussion and recommendations. Clin Oral Investig 17(Suppl 1):S73–S76CrossRefPubMed
6.
go back to reference Seong J, Macdonald E, Newcombe RG, Davies M, Jones SB, Johnson S, West NX (2013) In situ randomised trial to investigate the occluding properties of two desensitising toothpastes on dentine after subsequent acid challenge. Clin Oral Investig 17:195–203CrossRefPubMed Seong J, Macdonald E, Newcombe RG, Davies M, Jones SB, Johnson S, West NX (2013) In situ randomised trial to investigate the occluding properties of two desensitising toothpastes on dentine after subsequent acid challenge. Clin Oral Investig 17:195–203CrossRefPubMed
7.
go back to reference Pamir T, Özyazici M, Baloglu E, Önal B (2005) The efficacy of three desensitizing agents in treatment of dentine hypersensitivity. J Clin Pharm Ther 30:73–76CrossRefPubMed Pamir T, Özyazici M, Baloglu E, Önal B (2005) The efficacy of three desensitizing agents in treatment of dentine hypersensitivity. J Clin Pharm Ther 30:73–76CrossRefPubMed
8.
go back to reference Duran I, Sengun A (2004) The long-term effectiveness of five current desensitizing products on cervical dentine sensitivity. J Oral Rehabil 31:351–356CrossRefPubMed Duran I, Sengun A (2004) The long-term effectiveness of five current desensitizing products on cervical dentine sensitivity. J Oral Rehabil 31:351–356CrossRefPubMed
9.
go back to reference Kara C, Orbak R (2009) Comparative evaluation of Nd:YAG laser and fluoride varnish for the treatment of dentinal hypersensitivity. J Endod 35:971–974CrossRefPubMed Kara C, Orbak R (2009) Comparative evaluation of Nd:YAG laser and fluoride varnish for the treatment of dentinal hypersensitivity. J Endod 35:971–974CrossRefPubMed
10.
go back to reference Ritter AV, de L Dias W, Miguez P, Caplan DJ, Swift EJ Jr (2006) Treating cervical dentin hypersensitivity with fluoride varnish. A randomized clinical study. J Am Dent Assoc 137:1013–1020CrossRefPubMed Ritter AV, de L Dias W, Miguez P, Caplan DJ, Swift EJ Jr (2006) Treating cervical dentin hypersensitivity with fluoride varnish. A randomized clinical study. J Am Dent Assoc 137:1013–1020CrossRefPubMed
11.
go back to reference Polderman RN, Frencken JE (2007) Comparison between effectiveness of a low-viscosity glass ionomer and a resin-based glutaraldehyde containing primer in treating dentine hypersensitivity: a 25.2-month evaluation. J Dent 35:144–149CrossRefPubMed Polderman RN, Frencken JE (2007) Comparison between effectiveness of a low-viscosity glass ionomer and a resin-based glutaraldehyde containing primer in treating dentine hypersensitivity: a 25.2-month evaluation. J Dent 35:144–149CrossRefPubMed
12.
go back to reference Jain P, Reinhardt JW, Krell KV (2000) Effect of dentin desensitisers and dentin bonding agents on dentin permeability. Am J Dent 13:21–27PubMed Jain P, Reinhardt JW, Krell KV (2000) Effect of dentin desensitisers and dentin bonding agents on dentin permeability. Am J Dent 13:21–27PubMed
13.
go back to reference Ferrari M, Cagidiaco MC, Kugel G, Davidson CL (1999) Clinical evaluation of a one-bottle bonding system for desensitizing exposed roots. Am J Dent 12:243–249PubMed Ferrari M, Cagidiaco MC, Kugel G, Davidson CL (1999) Clinical evaluation of a one-bottle bonding system for desensitizing exposed roots. Am J Dent 12:243–249PubMed
14.
go back to reference Rusin RP, Agee K, Suchko M, Pashley DH (2010) Effect of a new liner/base on human dentin permeability. J Dent 38:245–252CrossRefPubMed Rusin RP, Agee K, Suchko M, Pashley DH (2010) Effect of a new liner/base on human dentin permeability. J Dent 38:245–252CrossRefPubMed
15.
go back to reference Abed AM, Mahdian M, Seifi M, Ziaei SA, Shamsaei M (2011) Comparative assessment of the sealing ability of Nd:YAG laser versus a new desensitizing agent in human dentinal tubules: a pilot study. Odontology 99:45–48CrossRefPubMed Abed AM, Mahdian M, Seifi M, Ziaei SA, Shamsaei M (2011) Comparative assessment of the sealing ability of Nd:YAG laser versus a new desensitizing agent in human dentinal tubules: a pilot study. Odontology 99:45–48CrossRefPubMed
16.
go back to reference Hansen EK (1992) Dentine hypersensitivity treated with a fluoride containing varnish or a light cured glass-ionomer liner. Scand J Dent Res 100:305–309PubMed Hansen EK (1992) Dentine hypersensitivity treated with a fluoride containing varnish or a light cured glass-ionomer liner. Scand J Dent Res 100:305–309PubMed
17.
go back to reference Suge T, Ishikawa K, Kavasaki A, Yoshiyama M, Asaoka K, Ebisu S (1995) Duration of dentinal tubule occlusion formed by calcium phosphate precipitation method: in vitro evaluation using synthetic saliva. J Dent Res 74:1709–1714CrossRefPubMed Suge T, Ishikawa K, Kavasaki A, Yoshiyama M, Asaoka K, Ebisu S (1995) Duration of dentinal tubule occlusion formed by calcium phosphate precipitation method: in vitro evaluation using synthetic saliva. J Dent Res 74:1709–1714CrossRefPubMed
18.
go back to reference Hoang-Dao BT, Hoang-Tu H, Tran- Hung L, Camps J, Koubi G, About I (2008) Evaluation of a natural resin-based new material (Shellac F) as a potential desensitizing agent. Dent Mater 24:1001–1007CrossRefPubMed Hoang-Dao BT, Hoang-Tu H, Tran- Hung L, Camps J, Koubi G, About I (2008) Evaluation of a natural resin-based new material (Shellac F) as a potential desensitizing agent. Dent Mater 24:1001–1007CrossRefPubMed
19.
go back to reference Davidson DF, Suzuki M (1997) The gluma bonding system: a clinical evaluation of its various components for the treatment of hypersensitive dentin. J Can Dent Assoc 63:38–41PubMed Davidson DF, Suzuki M (1997) The gluma bonding system: a clinical evaluation of its various components for the treatment of hypersensitive dentin. J Can Dent Assoc 63:38–41PubMed
20.
go back to reference Milia E, Castelli G, Bortone A, Sotgiu G, Manunta A, Pinna R, Gallina G (2013) Short-term response of three resin-based materials as desensitizing agents under oral environmental exposure. Acta Odontol Scand 71:599–609CrossRefPubMed Milia E, Castelli G, Bortone A, Sotgiu G, Manunta A, Pinna R, Gallina G (2013) Short-term response of three resin-based materials as desensitizing agents under oral environmental exposure. Acta Odontol Scand 71:599–609CrossRefPubMed
21.
go back to reference Wej Y, Silikas N, Zhang Z, Watts DC (2011) Diffusion and concurrent solubility of self-adhering and new resin–matrix composites during water sorption/desorption cycles. Dent Mater 27:197–205CrossRef Wej Y, Silikas N, Zhang Z, Watts DC (2011) Diffusion and concurrent solubility of self-adhering and new resin–matrix composites during water sorption/desorption cycles. Dent Mater 27:197–205CrossRef
22.
go back to reference Ozel Bektas O, Eren D, Akin EG, Akin H (2013) Evaluation of a self-adhering flowable composite in terms of micro-shear bond strength and microleakage. Acta Odontol Scand 71:541–546CrossRef Ozel Bektas O, Eren D, Akin EG, Akin H (2013) Evaluation of a self-adhering flowable composite in terms of micro-shear bond strength and microleakage. Acta Odontol Scand 71:541–546CrossRef
23.
go back to reference Poitevin A, De Munck J, Van Ende A, Suyama Y, Mine A, Peumans M, Van Meerbeek B (2013) Bonding effectiveness of self-adhesive composites to dentin and enamel. Dent Mater 29(2):221–230CrossRefPubMed Poitevin A, De Munck J, Van Ende A, Suyama Y, Mine A, Peumans M, Van Meerbeek B (2013) Bonding effectiveness of self-adhesive composites to dentin and enamel. Dent Mater 29(2):221–230CrossRefPubMed
24.
go back to reference Vichi A, Margvelashvili M, Goracci C, Papacchini F, Ferrari M (2013) Bonding and sealing ability of a new self-adhering flowable composite resin in class I restorations. Clin Oral Investig 17(6):1497–1506CrossRefPubMed Vichi A, Margvelashvili M, Goracci C, Papacchini F, Ferrari M (2013) Bonding and sealing ability of a new self-adhering flowable composite resin in class I restorations. Clin Oral Investig 17(6):1497–1506CrossRefPubMed
25.
go back to reference Dickens SH, Flaim GM, Takagi S (2003) Mechanical properties and biochemical activity of remineralizing resin-based Ca-PO4 cements. Dent Mater 19:558–566CrossRefPubMed Dickens SH, Flaim GM, Takagi S (2003) Mechanical properties and biochemical activity of remineralizing resin-based Ca-PO4 cements. Dent Mater 19:558–566CrossRefPubMed
26.
go back to reference Langhorst SE, O'Donnell JN, Skrtic D (2009) In vitro remineralization of enamel by polymeric amorphous calcium phosphate composite: quantitative microradiographic study. Dent Mater 25:884–891PubMedCentralCrossRefPubMed Langhorst SE, O'Donnell JN, Skrtic D (2009) In vitro remineralization of enamel by polymeric amorphous calcium phosphate composite: quantitative microradiographic study. Dent Mater 25:884–891PubMedCentralCrossRefPubMed
27.
go back to reference Wang Z, Sa Y, Sauro S, Chen H, Xing W, Ma X, Jiang T, Wang Y (2010) Effect of desensitizing toothpastes on dentinal tubule occlusion: a dentine permeability measurement and SEM in vitro study. J Dent 38:400–410CrossRefPubMed Wang Z, Sa Y, Sauro S, Chen H, Xing W, Ma X, Jiang T, Wang Y (2010) Effect of desensitizing toothpastes on dentinal tubule occlusion: a dentine permeability measurement and SEM in vitro study. J Dent 38:400–410CrossRefPubMed
28.
go back to reference Simonsen RJ (1991) Retention and effectiveness of dental sealant after 15 years. J Am Dent Assoc 122:34–42CrossRefPubMed Simonsen RJ (1991) Retention and effectiveness of dental sealant after 15 years. J Am Dent Assoc 122:34–42CrossRefPubMed
29.
go back to reference Papacchini F, Goracci C, Sadek FT, Monticelli F, Garcia-Godoy F, Ferrari M (2005) Microtensile bond strength to ground enamel by glass-ionomers, resin-modified glass-ionomers, and resin composites used as pit and fissure sealants. J Dent 33:459–467CrossRefPubMed Papacchini F, Goracci C, Sadek FT, Monticelli F, Garcia-Godoy F, Ferrari M (2005) Microtensile bond strength to ground enamel by glass-ionomers, resin-modified glass-ionomers, and resin composites used as pit and fissure sealants. J Dent 33:459–467CrossRefPubMed
30.
go back to reference Pardi V, Sinhoreti MAC, Pereira AC, Ambrosano GMB, Meneghim M (2006) In vitro evaluation of microleakage of different materials used as pit-and-fissure sealants. Braz Dent J 17:49–52CrossRefPubMed Pardi V, Sinhoreti MAC, Pereira AC, Ambrosano GMB, Meneghim M (2006) In vitro evaluation of microleakage of different materials used as pit-and-fissure sealants. Braz Dent J 17:49–52CrossRefPubMed
31.
go back to reference Cherng AM, Chow LC, Takagi S (2004) Reduction in dentin permeability using mildly supersaturated calcium phosphate solutions. Arch Oral Biol 49:91–98CrossRefPubMed Cherng AM, Chow LC, Takagi S (2004) Reduction in dentin permeability using mildly supersaturated calcium phosphate solutions. Arch Oral Biol 49:91–98CrossRefPubMed
32.
go back to reference Markowitz K, Pashley DH (2007) Discovering new treatments for sensitive teeth: the long path from biology to therapy. J Oral Rehabil 35:300–315CrossRef Markowitz K, Pashley DH (2007) Discovering new treatments for sensitive teeth: the long path from biology to therapy. J Oral Rehabil 35:300–315CrossRef
33.
go back to reference Söderholm KJ, Zigan M, Ragan M, Fischlschweiger W, Bergman M (1984) Hydrolytic degradation of dental composites. J Dent Res 63:1248–1254CrossRefPubMed Söderholm KJ, Zigan M, Ragan M, Fischlschweiger W, Bergman M (1984) Hydrolytic degradation of dental composites. J Dent Res 63:1248–1254CrossRefPubMed
34.
go back to reference Ferracane JL (2006) Hygroscopic and hydrolytic effects in dental polymer networks. Dent Mater 22:211–222CrossRefPubMed Ferracane JL (2006) Hygroscopic and hydrolytic effects in dental polymer networks. Dent Mater 22:211–222CrossRefPubMed
35.
go back to reference Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, Coutinho E, Suzuki K, Lambrechts P, Van Meerbeek B (2007) Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials 28:3757–3785CrossRefPubMed Van Landuyt KL, Snauwaert J, De Munck J, Peumans M, Yoshida Y, Poitevin A, Coutinho E, Suzuki K, Lambrechts P, Van Meerbeek B (2007) Systematic review of the chemical composition of contemporary dental adhesives. Biomaterials 28:3757–3785CrossRefPubMed
36.
go back to reference Yoshida Y, Nagakane K, Fukuda R, Nakayama Y, Okazaki M, Shintani H, Inoue S, Tagawa Y, Suzuki K, De Munck J, Van Meerbeek B (2004) Comparative study on adhesive performance of functional monomers. J Dent Res 83:454–458CrossRefPubMed Yoshida Y, Nagakane K, Fukuda R, Nakayama Y, Okazaki M, Shintani H, Inoue S, Tagawa Y, Suzuki K, De Munck J, Van Meerbeek B (2004) Comparative study on adhesive performance of functional monomers. J Dent Res 83:454–458CrossRefPubMed
37.
go back to reference Milia E, Cumbo E, Cardoso RJ, Gallina G (2012) Current dental adhesives systems. A narrative review. Curr Pharm Des 18:5542–5552CrossRefPubMed Milia E, Cumbo E, Cardoso RJ, Gallina G (2012) Current dental adhesives systems. A narrative review. Curr Pharm Des 18:5542–5552CrossRefPubMed
38.
go back to reference Mccabe JF, Carrick TE, Rusby S (2000) Properties of a composite containing pre-reacted glass ionomer filler. J Dent Res 79:36–37 Mccabe JF, Carrick TE, Rusby S (2000) Properties of a composite containing pre-reacted glass ionomer filler. J Dent Res 79:36–37
Metadata
Title
Clinical evaluation of the efficacy of one self-adhesive composite in dental hypersensitivity
Authors
R. Pinna
A. Bortone
G. Sotgiu
S. Dore
P. Usai
E. Milia
Publication date
01-09-2015
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 7/2015
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-014-1390-3

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