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01-07-2020 | Severe Acute Respiratory Syndrome Coronavirus | Review

The emergence of SARS, MERS and novel SARS-2 coronaviruses in the 21st century

Authors: Vivaldo Gomes da Costa, Marcos Lázaro Moreli, Marielena Vogel Saivish

Published in: Archives of Virology | Issue 7/2020

Abstract

At the beginning of the 21st century, a new deadly infectious disease known as severe acute respiratory syndrome (SARS) was recognized as a global public health threat. Subsequently, ten years after the initial SARS cases occurred in 2002, new cases of another atypical respiratory disease caused worldwide concern. This disease became known as Middle East respiratory syndrome (MERS) and was even more lethal than SARS. Currently, history has repeated itself with the emergence of a new Chinese epidemic at the end of 2019. For this respiratory disease, called COVID-19, a novel coronavirus (SARS-CoV-2) was identified as the etiologic agent. In sum, SARS, MERS and COVID-19 are caused by recently discovered coronaviruses that cause flu-like illnesses, but with a clinical outcome that tends to be more severe. As a result of the current importance of coronaviruses in global public health, we conducted a review to summarize and update, above all, the epidemiological historical aspects of the three major diseases in humans caused by coronaviral infection.

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Title: The emergence of SARS, MERS and novel SARS-2 coronaviruses in the 21st century
Authors: Vivaldo Gomes da Costa
Marcos Lázaro Moreli
Marielena Vogel Saivish
Publication date: 01-07-2020
Publisher: Springer Vienna
Keywords: Severe Acute Respiratory Syndrome Coronavirus
SARS-CoV-2
Middle Eastern Respiratory Syndrome
COVID-19
Coronavirus
Published in: Archives of Virology / Issue 7/2020
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI: https://doi.org/10.1007/s00705-020-04628-0

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