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Archives of Virology
Published in: Archives of Virology 10/2018

01-10-2018 | Original Article

Genomic characterization of GII.3 noroviruses isolated from children in Zhengzhou city, China, 2015/16

Authors: Jinjin Liu, Sanjing Li, Chao Wang, Lijun Zheng, Jie Ma, Chunwei Li, Yuqi Huo, Yumei Wang

Published in: Archives of Virology | Issue 10/2018

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Abstract

In this study, we isolated, amplified and sequenced GII.3 norovirus (NoV) strains from children admitted to a department of pediatric gastroenterology presenting with acute gastroenteritis from September 2015 to March 2016. A total of 35 stool samples were collected and eight were GII.3 NoV positive, based on sequencing. The complete genome sequences were determined for two strains while partial genome sequences, encompassing approximately 3.2 kb of the 3´end, were generated for the six other strains. Genotyping analysis of all strains indicated that they belonged to GII P12/GII.3. Phylogenetic analysis indicated that these isolated strains could be divided into two clusters. Strains in cluster IV were the most frequently isolated and exhibited less intra-cluster variation in nucleotide sequences. Our study demonstrated that the GII.P12/GII.3 recombinant strain was the dominant GII.3 NoVs in Zhengzhou city.
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Metadata
Title
Genomic characterization of GII.3 noroviruses isolated from children in Zhengzhou city, China, 2015/16
Authors
Jinjin Liu
Sanjing Li
Chao Wang
Lijun Zheng
Jie Ma
Chunwei Li
Yuqi Huo
Yumei Wang
Publication date
01-10-2018
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 10/2018
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-018-3905-8

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