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Archives of Virology
Published in: Archives of Virology 5/2015

Open Access 01-05-2015 | Brief Report

Echovirus 7 associated with hand, foot, and mouth disease in mainland China has undergone a recombination event

Authors: Xin Yao, Lian-Lian Bian, Qun-Ying Mao, Feng-Cai Zhu, Qiang Ye, Zheng-Lun Liang

Published in: Archives of Virology | Issue 5/2015

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Abstract

To investigate the evolution of echovirus 7 (Echo7) strains and the relationship between Echo7 strains and the prototype strain Wallace, phylogenetic analysis of Echo7 strains prevailing in mainland China was performed. The Echo7 strain, DH22G/JS/2012 was isolated from a 32-month-old boy who was clinically diagnosed with HFMD. The complete genome sequence of this isolate was determined after the virus was propagated in cell culture. Phylogenetic analysis showed that the subgroups B1 and C1 prevailed in mainland China from 1998 to 2012 and that the subgroup B2 began to circulate in mainland China in 2009. The result of Simplot analysis showed that the Echo7 strain DH22G/JS/2012 is a recombinant coxsackievirus B4 (CVB4) that circulated in mainland China in 2010.
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Metadata
Title
Echovirus 7 associated with hand, foot, and mouth disease in mainland China has undergone a recombination event
Authors
Xin Yao
Lian-Lian Bian
Qun-Ying Mao
Feng-Cai Zhu
Qiang Ye
Zheng-Lun Liang
Publication date
01-05-2015
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 5/2015
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-015-2350-1

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Keynote webinar | Spotlight on medication adherence

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