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Archives of Virology
Published in: Archives of Virology 6/2008

01-06-2008 | Brief Report

Identification of a recombinant dengue virus type 1 with 3 recombination regions in natural populations in Guangdong province, China

Authors: S.-P. Chen, M. Yu, T. Jiang, Y.-Q. Deng, C.-F. Qin, J.-F. Han, E.-D. Qin

Published in: Archives of Virology | Issue 6/2008

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Abstract

Using recombination analysis, we identified a recombinant dengue virus type 1 strain, namely, GD23/95, with three recombination regions, located within the sequences of the prM/E junction, NS1, and NS3, respectively. The recombinant dengue virus was further confirmed by phylogenetic analysis based on its recombination and non-recombination regions. This appears to be the first study to confirm the existence of three recombination regions in a single dengue virus isolate and to report recombination between parent virus strains isolated from the same geographic area (Guangdong province, China). It is also the first to report breakpoints within the NS3 gene of dengue viruses.
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Metadata
Title
Identification of a recombinant dengue virus type 1 with 3 recombination regions in natural populations in Guangdong province, China
Authors
S.-P. Chen
M. Yu
T. Jiang
Y.-Q. Deng
C.-F. Qin
J.-F. Han
E.-D. Qin
Publication date
01-06-2008
Publisher
Springer Vienna
Published in
Archives of Virology / Issue 6/2008
Print ISSN: 0304-8608
Electronic ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-008-0090-1

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