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Published in: Surgery Today 8/2018

01-08-2018 | Original Article

Surgical outcomes after gastrectomy in very elderly patients with gastric cancer

Authors: Makoto Hikage, Masanori Tokunaga, Rie Makuuchi, Tomoyuki Irino, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Masanori Terashima

Published in: Surgery Today | Issue 8/2018

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Abstract

Purpose

Whether or not gastrectomy is feasible for very elderly gastric cancer patients is unclear. This study aimed to clarify the feasibility and safety of surgical treatment for patients in this age group.

Method

The study included 55 very elderly patients with resectable gastric cancer who underwent gastrectomy (≥ 85 years of age; very-E group). The surgical outcomes were compared with those of 611 elderly patients (75–84 years old; E group).

Results

Female sex, a poor physical and performance status, and a low serum albumin level patients were more frequent in the very-E group than in the E group. Lymphadenectomy was less aggressive in the very-E group than in the E group (P < 0.001). The overall postoperative complication rate was not significantly different between the groups (46 vs 33%; P = 0.073). A multivariate analysis to predict the overall survival identified male sex (hazard ratio 1.75, 95% confidence interval 1.30–2.36), low body mass index (2.19, 1.52–3.16), poor performance status (2.14, 1.60–2.86), low serum albumin level (1.84, 1.37–2.48), and advanced tumor stage (1.71, 1.29–2.27) but not age (1.31, 0.84–2.03) as independent prognostic factors.

Conclusion

Chronological age alone is not a contraindicative factor for gastrectomy in very elderly patients.
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Metadata
Title
Surgical outcomes after gastrectomy in very elderly patients with gastric cancer
Authors
Makoto Hikage
Masanori Tokunaga
Rie Makuuchi
Tomoyuki Irino
Yutaka Tanizawa
Etsuro Bando
Taiichi Kawamura
Masanori Terashima
Publication date
01-08-2018
Publisher
Springer Singapore
Published in
Surgery Today / Issue 8/2018
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-018-1651-x

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