Published in:
01-02-2017 | Letter to the Editor
The need for differentiating diabetes-specific mortality from total mortality when comparing metformin with insulin regarding cancer survival
Authors:
Min Wei, Yu Liu, Chunhong Wang, Chuanhua Yu, Dejia Li, Wei Zhou, Zhi-Jiang Zhang
Published in:
Acta Diabetologica
|
Issue 2/2017
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Excerpt
Fransgaard and colleague examined the association between metformin and overall survival after surgical resection for colorectal cancer (CRC) [
1]. The adjusted hazard ratio was 0.85 (95% confidence interval 0.73–0.93,
P = 0.03) for the metformin-treated group compared with the insulin-treated group. The effect estimates for other oral antidiabetic medication (hazard ratio 0.91) and diet (hazard ratio 0.84) were not statistically significant, but was comparable to that of metformin. …