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Supportive Care in Cancer
Published in: Supportive Care in Cancer 8/2019

01-08-2019 | Original Article

Effects of a 12-week home-based exercise program on quality of life, psychological health, and the level of physical activity in colorectal cancer survivors: a randomized controlled trial

Authors: Ji Young Kim, Mi Kyung Lee, Dong Hoon Lee, Dong Woo Kang, Ji Hee Min, Ji Won Lee, Sang Hui Chu, Min Su Cho, Nam Kyu Kim, Justin Y. Jeon

Published in: Supportive Care in Cancer | Issue 8/2019

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Abstract

Purpose

To examine the effects of a home-based exercise program on quality of life (QOL), psychological health, and the level of physical activity (PA) in colorectal cancer survivors.

Methods

Seventy-one colorectal cancer survivors were randomized into either a home-based exercise group (N = 37) or control group (N = 34). The home-based exercise program included unsupervised walking, stationary bike, or swimming for aerobic exercise, as well as resistance exercise DVDs, a pedometer, and an exercise log. The Functional Assessment of Cancer Therapy-Colorectal, Functional Assessment of Chronic Illness Therapy-Fatigue Scale, patient health questionnaire, and Godin Leisure-Time Exercise Questionnaire were used to assess QOL, fatigue, depression, and PA levels.

Results

Among the 71 participants, 30 in the exercise group and 28 in the control group completed the study. The change in the QOL between the intervention and control groups was insignificant. However, QOL was significantly improved in the exercise group (QOL, p = 0.024). Sub-domain of QOL, emotional well-being, and trial outcome index-physical/functional/colorectal (p = 0.015 and p = 0.035, respectively) were improved in the exercise group. The level of PA was significantly increased after 12 weeks in the exercise group (97.0 ± 188.5 vs. 332.6 ± 306.1, p < 0.001), and the change significantly differed compared with the control group (mean change 235.6 vs. 16.3, p < 0.001).

Conclusions

The home-based exercise program may improve the QOL and psychological health in colorectal cancer survivors. We have demonstrated that the home-based exercise program was effective in increasing the level of PA in colorectal cancer survivors.
Literature
1.
GLOBOCAN (2008) Cancer incidence, mortality and prevalence worldwide in 2008. 2012-02-26]. http://​globocan.​ iarc. fr. 2013
2.
American Cancer Society (2011) Global cancer facts and figures. 2nd Edition. Atlanta, GA: American Cancer Society. 2011
3.
Coleman MP, Rachet B, Woods LM, Mitry E, Riga M, Cooper N, Quinn MJ, Brenner H, Estève J (2004) Trends and socioeconomic inequalities in cancer survival in England and Wales up to 2001. Br J Cancer 90(7):1367–1373CrossRefPubMedPubMedCentral
4.
Courneya KS, Friedenreich CM, Sela RA, Quinney HA, Rhodes RE, Handman M (2003) The group psychotherapy and home-based physical exercise (group-hope) trial in cancer survivors: physical fitness and quality of life outcomes. Psychooncology 12(4):357–374CrossRefPubMed
5.
6.
Mitchell AJ, Chan M, Bhatti H, Halton M, Grassi L, Johansen C, Meader N (2011) Prevalence of depression, anxiety, and adjustment disorder in oncological, haematological, and palliative-care settings: a meta-analysis of 94 interview-based studies. Lancet Oncol 12(2):160–174CrossRefPubMed
7.
Zabora J, BrintzenhofeSzoc K, Curbow B, Hooker C, Piantadosi S (2001) The prevalence of psychological distress by cancer site. Psychooncology 10(1):19–28CrossRefPubMed
8.
Sharma A, Walker AA, Sharp DM, Monson JRT, Walker LG (2007) Psychosocial factors and quality of life in colorectal cancer. Surgeon 5(6):344–354CrossRefPubMed
9.
Lee DH, Kim JY, Lee MK, Lee C, Min JH, Jeong DH, Lee JW, Chu SH, Meyerhardt JA, Ligibel J, Jones LW, Kim NK, Jeon JY (2013) Effects of a 12-week home-based exercise program on the level of physical activity, insulin, and cytokines in colorectal cancer survivors: a pilot study. Support Care Cancer 21(9):2537–2545CrossRefPubMed
10.
Ligibel JA, Meyerhardt J, Pierce JP, Najita J, Shockro L, Campbell N, Newman VA, Barbier L, Hacker E, Wood M, Marshall J, Paskett E, Shapiro C (2012) Impact of a telephone-based physical activity intervention upon exercise behaviors and fitness in cancer survivors enrolled in a cooperative group setting. Breast Cancer Res Treat 132(1):205–213CrossRefPubMed
11.
Morey MC, Snyder DC, Sloane R, Cohen HJ, Peterson B, Hartman TJ, Miller P, Mitchell DC, Demark-Wahnefried W (2009) Effects of home-based diet and exercise on functional outcomes among older, overweight long-term cancer survivors: RENEW: a randomized controlled trial. JAMA 301(18):1883–1891CrossRefPubMedPubMedCentral
12.
Courneya KS (2001) Exercise interventions during cancer treatment: biopsychosocial outcomes. Exerc Sport Sci Rev 29(2):60–64PubMed
13.
Courneya KS, Friedenreich CM, Quinney HA et al (2003) A randomized trial of exercise and quality of life in colorectal cancer survivors. Eur J Cancer Care (Engl) 12(4):347–357CrossRef
14.
Pinto BM, Papandonatos GD, Goldstein MG, Marcus BH, Farrell N (2013) Home-based physical activity intervention for colorectal cancer survivors. Psychooncology 22(1):54–64CrossRefPubMed
15.
Ligibel JA, Partridge A, Giobbie-Hurder A, Campbell N, Shockro L, Salinardi T, Winer EP (2010) Physical and psychological outcomes among women in a telephone-based exercise intervention during adjuvant therapy for early stage breast cancer. J Women’s Health (Larchmt) 19(8):1553–1559CrossRef
16.
Pinto BM, Frierson GM, Rabin C, Trunzo JJ, Marcus BH (2005) Home-based physical activity intervention for breast cancer patients. J Clin Oncol 23(15):3577–3587CrossRefPubMed
17.
Spector D, Deal AM, Amos KD, Yang H, Battaglini CL (2014) A pilot study of a home-based motivational exercise program for African American breast cancer survivors: clinical and quality-of-life outcomes. Integr Cancer Ther 13(2):121–132CrossRefPubMed
18.
Yang CY, Tsai JC, Huang YC, Lin CC (2011) Effects of a home-based walking program on perceived symptom and mood status in postoperative breast cancer women receiving adjuvant chemotherapy. J Adv Nurs 67(1):158–168CrossRefPubMed
19.
Lee MK, Kim JY, Kim DI, Kang DW, Park JH, Ahn KY, in Yang H, Lee DH, Roh YH, Lee JW, Chu SH, Meyerhardt JA, Jones LW, Kim NK, Jeon JY (2017) Effect of home-based exercise intervention on fasting insulin and Adipocytokines in colorectal cancer survivors: a randomized controlled trial. Metabolism 76:23–31CrossRefPubMed
20.
Meyerhardt JA, Giovannucci EL, Ogino S, Kirkner GJ, Chan AT, Willett W, Fuchs CS (2009) Physical activity and male colorectal cancer survival. Arch Intern Med 169(22):2102–2108CrossRefPubMedPubMedCentral
21.
Meyerhardt JA, Heseltine D, Niedzwiecki D et al (2006) Impact of physical activity on cancer recurrence and survival in patients with stage III colon cancer: findings from CALGB 89803. J Clin Oncol 24(22):3535–3541CrossRefPubMed
22.
Yoo HJ, Kim JC, Eremenco S, Han OS (2005) Quality of life in colorectal cancer patients with colectomy and the validation of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C), Version 4. J Pain Symptom Manag 30(1):24–32CrossRef
23.
Yost KJ, Cella D, Chawla A et al (2005) Minimally important differences were estimated for the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) instrument using a combination of distribution- and anchor-based approaches. J Clin Epidemiol 58(12):1241–1251CrossRefPubMed
24.
Cella D (1997) The Functional Assessment of Cancer Therapy-Anemia (FACT-An) Scale: a new tool for the assessment of outcomes in cancer anemia and fatigue. Semin Hematol 34(3 Suppl 2):13–19PubMed
25.
Cella D, Lai JS, Chang CH, Peterman A, Slavin M (2002) Fatigue in cancer patients compared with fatigue in the general United States population. Cancer 94(2):528–538CrossRefPubMed
26.
Gilbody S, Richards D, Brealey S, Hewitt C (2007) Screening for depression in medical settings with the Patient Health Questionnaire (PHQ): a diagnostic meta-analysis. J Gen Intern Med 22(11):1596–1602CrossRefPubMedPubMedCentral
27.
Godin G, Jobin J, Bouillon J (1986) Assessment of leisure time exercise behavior by self-report: a concurrent validity study. Can J Public Health 77(5):359–362PubMed
28.
Cella D, Eton DT, Lai JS, Peterman AH, Merkel DE (2002) Combining anchor and distribution-based methods to derive minimal clinically important differences on the Functional Assessment of Cancer Therapy (FACT) anemia and fatigue scales. J Pain Symptom Manag 24(6):547–561CrossRef
29.
Buffart LM, Thong MS, Schep G, et al (2012) Self-reported physical activity: its correlates and relationship with health-related quality of life in a large cohort of colorectal cancer survivors. PLoS One 7(5):e36164
30.
Lynch BM, Cerin E, Owen N, Hawkes AL, Aitken JF (2008) Prospective relationships of physical activity with quality of life among colorectal cancer survivors. J Clin Oncol 26(27):4480–4487CrossRefPubMed
31.
Peddle CJ, Au HJ, Courneya KS (2008) Associations between exercise, quality of life, and fatigue in colorectal cancer survivors. Dis Colon Rectum 51(8):1242–1248CrossRefPubMed
32.
Grimmett C, Bridgewater J, Steptoe A, Wardle J (2011) Lifestyle and quality of life in colorectal cancer survivors. Qual Life Res 20(8):1237–1245CrossRefPubMed
33.
Lewis C, Xun P, He K (2014) Physical activity in relation to quality of life in newly diagnosed colon cancer patients: a 24-month follow-up. Qual Life Res 23(8):2235–2246CrossRefPubMed
34.
Chung JY, Lee DH, Park JH, Lee MK, Kang DW, Min J, Kim DI, Jeong DH, Kim NK, Meyerhardt JA, Jones LW, Jeon JY (2013) Patterns of physical activity participation across the cancer trajectory in colorectal cancer survivors. Support Care Cancer 21(6):1605–1612CrossRefPubMed
35.
Blanchard CM, Courneya KS, Stein K, American Cancer Society’s SCS-II (2008) Cancer survivors’ adherence to lifestyle behavior recommendations and associations with health-related quality of life: results from the American Cancer Society’s SCS-II. J Clin Oncol 26(13):2198–2204CrossRefPubMed
36.
Park JH, Lee J, Oh M, Park H, Chae J, Kim DI, Lee MK, Yoon YJ, Lee CW, Park S, Jones LW, Kim NK, Kim SI, Jeon JY (2015) The effect of oncologists’ exercise recommendations on the level of exercise and quality of life in survivors of breast and colorectal cancer: a randomized controlled trial. Cancer 121(16):2740–2748CrossRefPubMed
37.
Jones LW, Courneya KS (2002) Exercise counseling and programming preferences of cancer survivors. Cancer Pract 10(4):208–215CrossRefPubMed
Metadata
Title
Effects of a 12-week home-based exercise program on quality of life, psychological health, and the level of physical activity in colorectal cancer survivors: a randomized controlled trial
Authors
Ji Young Kim
Mi Kyung Lee
Dong Hoon Lee
Dong Woo Kang
Ji Hee Min
Ji Won Lee
Sang Hui Chu
Min Su Cho
Nam Kyu Kim
Justin Y. Jeon
Publication date
01-08-2019
Publisher
Springer Berlin Heidelberg
Published in
Supportive Care in Cancer / Issue 8/2019
Print ISSN: 0941-4355
Electronic ISSN: 1433-7339
DOI
https://doi.org/10.1007/s00520-018-4588-0

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