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Pediatric Nephrology

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01-08-2013 | Original Article

Acute kidney injury according to pediatric RIFLE criteria is associated with negative outcomes after heart surgery in children

Authors: Michel Georges dos Santos El Halal, Paulo Roberto A. Carvalho

Published in: Pediatric Nephrology | Issue 8/2013

Abstract

Background

The aim of this study was to investigate the association between the occurrence of acute kidney injury (AKI) according to pediatric RIFLE (pRIFLE) criteria and adverse outcomes in children after heart surgery.

Methods

Children undergoing heart surgery in a tertiary hospital in Southern Brazil were followed during their stay in the pediatric intensive care unit (PICU) or until death. The exposure variable was occurrence of AKI according to pRIFLE criteria which place AKI in three categories: R (risk), I (injury), and F (failure). The outcomes studied were death, length of mechanical ventilation (MV), and length of PICU stay.

Results

Eighty-five children were enrolled in the study. Of these, 47 (55.3 %) did not have AKI, while 22 (25.9 %), seven (8.2 %), and nine (10.6 %) were classified into pRIFLE categories R, I, and F, respectively. The incidence of death was 18.4 and 4.2 % in patients with and without AKI, respectively. Compared to children who did not develop AKI, the adjusted odds ratio for death was 1.05 [95 % confidence interval (CI) 0.09–11.11], 8.36 (95 % CI 1.32–52.63), and 7.85 (95 % CI 1.53–40.29) in the R, I, and F groups, respectively (p = 0.022). Duration of MV and of PICU stay were significantly higher in those children with AKI.

Conclusions

The occurrence of AKI according to pRIFLE criteria is associated to adverse outcomes in children after heart surgery.

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Title: Acute kidney injury according to pediatric RIFLE criteria is associated with negative outcomes after heart surgery in children
Authors: Michel Georges dos Santos El Halal
Paulo Roberto A. Carvalho
Publication date: 01-08-2013
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 8/2013
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-013-2495-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Acute kidney injury according to pediatric RIFLE criteria is associated with negative outcomes after heart surgery in children

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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