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Published in:

01-07-2006 | Conference Report

Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement

Authors: John D. Mahan, Bradley A. Warady, Consensus Committee

Published in: Pediatric Nephrology | Issue 7/2006

Abstract

Growth failure is a clinically important issue in children with chronic kidney disease (CKD) and is associated with significant morbidity and mortality. Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH)–insulin-like growth factor-I (IGF-I) axis, malnutrition, acidosis, and renal bone disease. The management of growth failure in children with CKD is complicated by the presence of other disease-related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, some practitioners and families have been reluctant to institute GH therapy, citing an unwillingness to comply with daily injections, reimbursement difficulties, or impending renal transplantation. Suboptimal attention to growth failure management may be further compounded by a lack of clinical guidelines for the appropriate assessment and treatment of growth failure in these children. This review of growth failure in children with CKD concludes with an algorithm developed by members of the consensus committee, outlining their recommendations for appropriate steps to improve growth and overall health outcomes in children with CKD.

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Title: Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement
Authors: John D. Mahan
Bradley A. Warady
Consensus Committee
Publication date: 01-07-2006
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Nephrology / Issue 7/2006
Print ISSN: 0931-041X
Electronic ISSN: 1432-198X
DOI: https://doi.org/10.1007/s00467-006-0020-y

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Assessment and treatment of short stature in pediatric patients with chronic kidney disease: a consensus statement

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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