Skip to main content
Top
Published in: Surgical Endoscopy 7/2018

01-07-2018

15-year experience of laparoscopic single anastomosis (mini-)gastric bypass: comparison with other bariatric procedures

Authors: Nawaf Alkhalifah, Wei-Jei Lee, Tan Chun Hai, Kong-Han Ser, Jung-Chien Chen, Chun-Chi Wu

Published in: Surgical Endoscopy | Issue 7/2018

Login to get access

Abstract

Background

Laparoscopic single anastomosis (mini-)gastric bypass (LSAGB) has been validated as a safe and effective treatment for morbid obesity. However, data of the long-term outcome remain lacking.

Methods

Between October 2001 and December 2015, 1731 morbidly obese patients who received LSAGB as primary bariatric procedure at the Min-Sheng General Hospital were recruited. Surgical outcome, weight loss, resolution of comorbidities, and late complications were followed, then compared with groups of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG). All data derived from a prospective bariatric database and a retrospective analysis were conducted.

Results

The average patient age was 33.8 ± 10.4 years with a mean body mass index (BMI) of 40.4 ± 7.7 kg/m2. Of them, 70.0% were female while 30.0% were male. Mean operating time, intraoperative blood, and hospital stay of LSAGB were 124.6 ± 38.8 min, 39.5 ± 38.7 ml, and 5.0 ± 4.1 days, respectively. The 30-day post-operative major complication occurred in 30 (1.7%) of LSAGB patients, 16 (2.0%) of LRYGB, and 15 (1.4%) of LSG patients. The follow-up rates at 1, 5, and 10 years were 89.3, 52.1, and 43.6%, respectively. At postoperative 1, 5, and 10 years, the mean percentage of weight loss (%WL) of LSAGB patients were 32.7, 32.2, and 29.1%, and mean BMI became 27, 26.9, and 27 kg/m2, respectively. The LSAGB had a higher weight loss than LRYGB and LSG at 2–6 years after surgery. LSG had a lower remission rate in dyslipidemia comparing to LSAGB and LRYGB. The overall revision rate of LSAGB is 4.0% (70/1731) which was lower than the 5.1% in LRYGB and 5.2% in the LSG.

Conclusion

LSAGB is an effective procedure for treating morbid obesity and metabolic disorders, which results in sustained weight loss and a high resolution of comorbidities.
Literature
1.
go back to reference Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, Schoelles K (2004) Bariatric surgery: a systematic review and meta-analysis. JAMA 292:1724–1737CrossRefPubMed Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, Schoelles K (2004) Bariatric surgery: a systematic review and meta-analysis. JAMA 292:1724–1737CrossRefPubMed
2.
go back to reference Sjöström L, Narbro K, Sjöström CD, Karason K, Larsson B, Wedel H, Lystig T, Sullivan M, Bouchard C, Carlsson B, Bengtson C, Dahlgren S, Gummesson A, Jacobson P, Karlsson J, Lindroos AK, Lonroth H, Naslund I, Olbers T, Stenlof K, Torgerson J, Agren G, Carlsson L (2007) Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 357:741–752CrossRefPubMed Sjöström L, Narbro K, Sjöström CD, Karason K, Larsson B, Wedel H, Lystig T, Sullivan M, Bouchard C, Carlsson B, Bengtson C, Dahlgren S, Gummesson A, Jacobson P, Karlsson J, Lindroos AK, Lonroth H, Naslund I, Olbers T, Stenlof K, Torgerson J, Agren G, Carlsson L (2007) Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 357:741–752CrossRefPubMed
3.
4.
go back to reference Himpens J, Dobbeleir J, Peeters G (2010) Long-term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg 252:319–324CrossRefPubMed Himpens J, Dobbeleir J, Peeters G (2010) Long-term results of laparoscopic sleeve gastrectomy for obesity. Ann Surg 252:319–324CrossRefPubMed
5.
go back to reference Angrisani L, Santonicola A, Iovino P, Formisano G, Buchwald H, Scopinaro N (2015) Bariatric surgery worldwide 2013. Obes Surg 25:1822–1832CrossRefPubMed Angrisani L, Santonicola A, Iovino P, Formisano G, Buchwald H, Scopinaro N (2015) Bariatric surgery worldwide 2013. Obes Surg 25:1822–1832CrossRefPubMed
7.
go back to reference Noun R, Skaff J, Riachi E, Daher R, Antoun N, Nasr M (2012) One thousand consecutive mini-gastric bypass: short- and long-term outcome. Obes Surg 22:697–703CrossRefPubMed Noun R, Skaff J, Riachi E, Daher R, Antoun N, Nasr M (2012) One thousand consecutive mini-gastric bypass: short- and long-term outcome. Obes Surg 22:697–703CrossRefPubMed
8.
9.
go back to reference Tacchino RM, Greco F, Matera D, Diflumeri G (2010) Single-incision laparoscopic gastric bypass for morbid obesity. Obes Surg 20:1154–1160CrossRefPubMed Tacchino RM, Greco F, Matera D, Diflumeri G (2010) Single-incision laparoscopic gastric bypass for morbid obesity. Obes Surg 20:1154–1160CrossRefPubMed
10.
go back to reference Bruzzi M, Rau C, Voron T, Guenzi M, Berqer A, Chevallier JM (2015) Single anastomosis or mini-gastric bypass: long-term results and quality of life after a 5-year follow-up. Surg Obes Relat Dis 11:321–326CrossRefPubMed Bruzzi M, Rau C, Voron T, Guenzi M, Berqer A, Chevallier JM (2015) Single anastomosis or mini-gastric bypass: long-term results and quality of life after a 5-year follow-up. Surg Obes Relat Dis 11:321–326CrossRefPubMed
11.
go back to reference Fisher BL, Buchwald H, Clark W et al (2001) Mini-gastric bypass controversy. Obes Surg 11(6):773–777PubMed Fisher BL, Buchwald H, Clark W et al (2001) Mini-gastric bypass controversy. Obes Surg 11(6):773–777PubMed
12.
go back to reference Lee WJ, Lin YH (2014) Single-anastomosis gastric bypass (SAGB): appraisal of clinical evidence. Obes Surg 24:1749–1756CrossRefPubMed Lee WJ, Lin YH (2014) Single-anastomosis gastric bypass (SAGB): appraisal of clinical evidence. Obes Surg 24:1749–1756CrossRefPubMed
13.
go back to reference Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240:205–213CrossRefPubMedPubMedCentral
14.
go back to reference Ser KH, Lee WJ, Lee YC, Chen JC, Su YH, Chen SC (2010) Experience in laparoscopic sleeve gastrectomy for morbidly obese Taiwanese: staple-line reinforcement is important for preventing leakage. Surg Endosc 24(9):2253–2259CrossRefPubMed Ser KH, Lee WJ, Lee YC, Chen JC, Su YH, Chen SC (2010) Experience in laparoscopic sleeve gastrectomy for morbidly obese Taiwanese: staple-line reinforcement is important for preventing leakage. Surg Endosc 24(9):2253–2259CrossRefPubMed
15.
go back to reference Pok EH, Lee WJ, Ser KH, Chen JC, Chen SC, Tsou JJ, Chin KF (2016) Laparoscopic sleeve gastrectomy in Asia: long term outcome and revisional surgery. Asian J Surg 39:21–28CrossRefPubMed Pok EH, Lee WJ, Ser KH, Chen JC, Chen SC, Tsou JJ, Chin KF (2016) Laparoscopic sleeve gastrectomy in Asia: long term outcome and revisional surgery. Asian J Surg 39:21–28CrossRefPubMed
16.
go back to reference Jammu G, Sharma R (2016) A 7-year clinical audit of 1107 cases comparing sleeve gastrectomy, Roux-en-Y gastric bypass and mini-gastric bypass, to determine an effective and safe bariatric and metabolic procedure. Obes Surg 26:926–932CrossRefPubMed Jammu G, Sharma R (2016) A 7-year clinical audit of 1107 cases comparing sleeve gastrectomy, Roux-en-Y gastric bypass and mini-gastric bypass, to determine an effective and safe bariatric and metabolic procedure. Obes Surg 26:926–932CrossRefPubMed
17.
go back to reference Genser L, Carandina S, Tabbara M, Torcivia A, Soprani A, Siksik JM, Cady J (2016) Presentation and surgical management of leaks after mini-gastric bypass for morbid obesity. Surg Obes Relat Dis 12:305–312CrossRefPubMed Genser L, Carandina S, Tabbara M, Torcivia A, Soprani A, Siksik JM, Cady J (2016) Presentation and surgical management of leaks after mini-gastric bypass for morbid obesity. Surg Obes Relat Dis 12:305–312CrossRefPubMed
18.
go back to reference Lee WJ, Ser KH, Lee YC, Tsou JJ, Chen SC, Chen JC (2012) Laparoscopic Roux-en-Y vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience. Obes Surg 27:623–631 Lee WJ, Ser KH, Lee YC, Tsou JJ, Chen SC, Chen JC (2012) Laparoscopic Roux-en-Y vs. mini-gastric bypass for the treatment of morbid obesity: a 10-year experience. Obes Surg 27:623–631
19.
go back to reference Paroz A, Calmes JM, Giusti V, Suter M (2006) Internal hernia after laparoscopic Roux-en-Y gastric bypass for morbid obesity: a continuous challenge in bariatric surgery. Obes Surg 16:1482–1487CrossRefPubMed Paroz A, Calmes JM, Giusti V, Suter M (2006) Internal hernia after laparoscopic Roux-en-Y gastric bypass for morbid obesity: a continuous challenge in bariatric surgery. Obes Surg 16:1482–1487CrossRefPubMed
20.
go back to reference Chowbey P, Baijal M, Kantharia N, Khullar R, Sharma A, Soni V (2016) Mesenteric defect closure decreases the incidence of internal hernias following laparoscopic Roux-en-Y gastric bypass: a retrospective cohort study. Obes Surg 26:2029–2034CrossRefPubMed Chowbey P, Baijal M, Kantharia N, Khullar R, Sharma A, Soni V (2016) Mesenteric defect closure decreases the incidence of internal hernias following laparoscopic Roux-en-Y gastric bypass: a retrospective cohort study. Obes Surg 26:2029–2034CrossRefPubMed
21.
go back to reference Koner J, Inabnet W, Febres G, Conwell I, McMahon D, Salas R, Taveras C, Schrope B, Bessler M (2009) Prospective study of gut hormone and metabolic changes after adjustable gastric banding and Roux-en-Y gastric bypass. Int J Obes 33:786–793CrossRef Koner J, Inabnet W, Febres G, Conwell I, McMahon D, Salas R, Taveras C, Schrope B, Bessler M (2009) Prospective study of gut hormone and metabolic changes after adjustable gastric banding and Roux-en-Y gastric bypass. Int J Obes 33:786–793CrossRef
22.
go back to reference Lee WJ, Chen CY, Chong K, Lee YC, Chen SC, Lee SD (2011) Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy. Surg Obes Relat Dis 7:683–690CrossRefPubMed Lee WJ, Chen CY, Chong K, Lee YC, Chen SC, Lee SD (2011) Changes in postprandial gut hormones after metabolic surgery: a comparison of gastric bypass and sleeve gastrectomy. Surg Obes Relat Dis 7:683–690CrossRefPubMed
23.
go back to reference Venciauskas L, Johannes S, Emst A et al (2014) Short vs. long biliopancreatic limb gastric bypass for treatment of T2DM, randomized controlled study. Obes Surg 24:1149–1150 Venciauskas L, Johannes S, Emst A et al (2014) Short vs. long biliopancreatic limb gastric bypass for treatment of T2DM, randomized controlled study. Obes Surg 24:1149–1150
24.
go back to reference Caruana JA, Monte SV, Jacobs DM, Voytovich C, Ghanim H, Dandona P (2015) Distal small bowel bypass for weight regain after gastric bypass: safety and efficacy threshold occurs at < 70% bypass. Surg Obes Relat Dis 11:1248–1256CrossRefPubMed Caruana JA, Monte SV, Jacobs DM, Voytovich C, Ghanim H, Dandona P (2015) Distal small bowel bypass for weight regain after gastric bypass: safety and efficacy threshold occurs at < 70% bypass. Surg Obes Relat Dis 11:1248–1256CrossRefPubMed
25.
go back to reference Miyachi T, Nagao M, Shikashi S, Kitahara Y, Tanaka N, Watanabe K, Tsuchiya T, Motoi F, Naitoh T, Unno M (2016) Biliopancreatic limb plays an important role in metabolic improvement after duodenal-jejunal bypass in a rat model of diabetes. Surgery 159(5):1360–1371CrossRefPubMed Miyachi T, Nagao M, Shikashi S, Kitahara Y, Tanaka N, Watanabe K, Tsuchiya T, Motoi F, Naitoh T, Unno M (2016) Biliopancreatic limb plays an important role in metabolic improvement after duodenal-jejunal bypass in a rat model of diabetes. Surgery 159(5):1360–1371CrossRefPubMed
26.
go back to reference Flum DR, Dellinger P (2004) Impact of gastric bypass operation on survival: a population-based analysis. J Am Coll Surg 199:543–551CrossRefPubMed Flum DR, Dellinger P (2004) Impact of gastric bypass operation on survival: a population-based analysis. J Am Coll Surg 199:543–551CrossRefPubMed
27.
go back to reference Lee WJ, Chong K, Ser KH, Lee YC, Chen SC, Chen JC, Tsai MH, Chung LM (2011) Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg 146(2):143–148CrossRefPubMed Lee WJ, Chong K, Ser KH, Lee YC, Chen SC, Chen JC, Tsai MH, Chung LM (2011) Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg 146(2):143–148CrossRefPubMed
28.
go back to reference Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, Thomas S, Abood B, Nissen SE, Bhatt DL (2012) Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med 366(17):1567–1576CrossRefPubMedPubMedCentral Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, Thomas S, Abood B, Nissen SE, Bhatt DL (2012) Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med 366(17):1567–1576CrossRefPubMedPubMedCentral
Metadata
Title
15-year experience of laparoscopic single anastomosis (mini-)gastric bypass: comparison with other bariatric procedures
Authors
Nawaf Alkhalifah
Wei-Jei Lee
Tan Chun Hai
Kong-Han Ser
Jung-Chien Chen
Chun-Chi Wu
Publication date
01-07-2018
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 7/2018
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-017-6011-1

Other articles of this Issue 7/2018

Surgical Endoscopy 7/2018 Go to the issue