Acute rheumatic fever in the Central Anatolia Region of Turkey: a 30-year experience in a single center

The study was carried out in Dr. Sami Ulus Children’s Hospital to investigate and to compare the incidence and findings of acute rheumatic fever patients (ARF) seen in the past 30 years. The medical records of 1,115 patients with ARF admitted to Dr. Sami Ulus Children’s Hospital Department of Pediatric Cardiology during 1980–2009 were retrospectively analyzed. Twenty-one percent of those patients were admitted between 1980 and 1989, 44.6% between 1990 and 1999, and 34.2% between 2000 and 2009. The highest incidence was detected in the second decade with a rate of 60.0:100,000. Male/female ratio was 1:18. The age of patients ranged between 2 and 15 years. Carditis was detected in 64.7% of patients, arthritis in 59.1%, and chorea in 14.1%. Mitral regurgitation was the most common echocardiographic finding. Heart failure was detected in 13.8%. Recurrent attacks occurred in 8.1% of patients. The median follow-up was 6.8 years (range, 1.2–10.5 years). The prevalence of chronic rheumatic valvular disease was 58%. Mortality rate was 0.8%. Conclusion: Although the incidence of ARF has decreased in the last decade, it still continues to be an important public health problem in Turkish pediatric population.