Skip to main content
Top
Published in: European Journal of Pediatrics 2/2012

01-02-2012 | Original Paper

Reducing VAP by instituting a care bundle using improvement methodology in a UK Paediatric Intensive Care Unit

Authors: Joe Brierley, Lorraine Highe, Sarah Hines, Garth Dixon

Published in: European Journal of Pediatrics | Issue 2/2012

Login to get access

Abstract

Preventing ventilator-associated pneumonia (VAP) is one of the Department of Health Saving Lives initiatives. We describe the institution of a purpose-designed bundle of care in a tertiary paediatric ICU based on the available literature as part of our hospital’s transformation project into reducing health-care-associated infection. A nurse-led VAP surveillance programme is in place, and we used this to compare VAP incidence before and after commencing a series of care measures aimed at reducing VAP as part of an overall drive for patient safety. The diagnostic criteria, surveillance methods and rates of VAP (5.6 per 1,000 ventilator days) have been previously reported. Nurse educators were added to the original core group, as a key feature is buy in from nursing staff. All nursing staff had multiple training opportunities, and VAP project education became a routine part of staff induction. The major features of the bundle of care were (1) elevation of bed to maximum (target, 45°; however, no beds currently permit this so achieved 20–30°), (2) mouth care using chlorhexidine or tooth brushing, (3) clean suctioning practice, (4) all patients not on full feeds commenced on ranitidine and (5) 4-hourly documentation. Compliance with these aspects was monitored. After the institution of the bundle, no paediatric case of VAP was recorded over a 12-month period, according to a priori definitions. One adult patient had a confirmed VAP over the same time interval. A paediatric VAP bundle was associated with reduced VAP on a UK PICU.
Literature
1.
go back to reference Abdel-Gawad T, El Hodhod M, Ibrahim H, Michael Y (2009) Gastroesophageal reflux in mechanically ventilated pediatric patients and its relation to ventilator-associated pneumonia. Crit Care 13:R164PubMedCrossRef Abdel-Gawad T, El Hodhod M, Ibrahim H, Michael Y (2009) Gastroesophageal reflux in mechanically ventilated pediatric patients and its relation to ventilator-associated pneumonia. Crit Care 13:R164PubMedCrossRef
2.
go back to reference Almuneef M, Memish ZA, Balkhy HH, Alalem H, Abutaleb A (2004) Ventilator-associated pneumonia in a pediatric intensive care unit in Saudi Arabia: a 30-month prospective surveillance. Infect Control Hosp Epidemiol 25:753–758PubMedCrossRef Almuneef M, Memish ZA, Balkhy HH, Alalem H, Abutaleb A (2004) Ventilator-associated pneumonia in a pediatric intensive care unit in Saudi Arabia: a 30-month prospective surveillance. Infect Control Hosp Epidemiol 25:753–758PubMedCrossRef
3.
go back to reference Berdal JE, Bjornholt J, Blomfeldt A, Smith-Erichsen N, Bukholm G (2007) Patterns and dynamics of airway colonisation in mechanically-ventilated patients. Clin Microbiol Infect 13:476–480PubMedCrossRef Berdal JE, Bjornholt J, Blomfeldt A, Smith-Erichsen N, Bukholm G (2007) Patterns and dynamics of airway colonisation in mechanically-ventilated patients. Clin Microbiol Infect 13:476–480PubMedCrossRef
4.
go back to reference Bigham MT, Amato R, Bondurrant P, Fridriksson J, Krawczeski CD, Raake J, Ryckman S, Schwartz S, Shaw J, Wells D, Brilli RJ (2009) Ventilator-associated pneumonia in the pediatric intensive care unit: characterizing the problem and implementing a sustainable solution. J Pediatr 154:582–587PubMedCrossRef Bigham MT, Amato R, Bondurrant P, Fridriksson J, Krawczeski CD, Raake J, Ryckman S, Schwartz S, Shaw J, Wells D, Brilli RJ (2009) Ventilator-associated pneumonia in the pediatric intensive care unit: characterizing the problem and implementing a sustainable solution. J Pediatr 154:582–587PubMedCrossRef
5.
go back to reference Brilli RJ, Sparling KW, Lake MR, Butcher J, Myers SS, Clark MD, Helpling A, Stutler ME (2008) The business case for preventing ventilator-associated pneumonia in pediatric intensive care unit patients. Jt Comm J Qual Patient Saf 34:629–638PubMed Brilli RJ, Sparling KW, Lake MR, Butcher J, Myers SS, Clark MD, Helpling A, Stutler ME (2008) The business case for preventing ventilator-associated pneumonia in pediatric intensive care unit patients. Jt Comm J Qual Patient Saf 34:629–638PubMed
6.
go back to reference Centers for Disease Control and Prevention (2011) Protocols and definitions for the ventilator-associated pneumonia option of the device-associated module of the patient safety component of the NHSN . Page Office of the Associate Director for Communication, Division of News and Electronic Media. Ref Type: Internet Communication Centers for Disease Control and Prevention (2011) Protocols and definitions for the ventilator-associated pneumonia option of the device-associated module of the patient safety component of the NHSN . Page Office of the Associate Director for Communication, Division of News and Electronic Media. Ref Type: Internet Communication
7.
go back to reference Cook D, Guyatt G, Marshall J, Leasa D, Fuller H, Hall R, Peters S, Rutledge F, Griffith L, McLellan A, Wood G, Kirby A, Tweeddale M, Pagliarello J, Johnston R, The Canadian Critical Care Trials Group (1998) A Comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. N Engl J Med 338:791–797PubMedCrossRef Cook D, Guyatt G, Marshall J, Leasa D, Fuller H, Hall R, Peters S, Rutledge F, Griffith L, McLellan A, Wood G, Kirby A, Tweeddale M, Pagliarello J, Johnston R, The Canadian Critical Care Trials Group (1998) A Comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. N Engl J Med 338:791–797PubMedCrossRef
8.
go back to reference Curley MA, Schwalenstocker E, Deshpande JK, Ganser CC, Bertoch D, Brandon J, Kurtin P (2006) Tailoring the Institute for Health Care Improvement 100,000 Lives Campaign to pediatric settings: the example of ventilator-associated pneumonia. Pediatr Clin North Am 53:1231–1251PubMedCrossRef Curley MA, Schwalenstocker E, Deshpande JK, Ganser CC, Bertoch D, Brandon J, Kurtin P (2006) Tailoring the Institute for Health Care Improvement 100,000 Lives Campaign to pediatric settings: the example of ventilator-associated pneumonia. Pediatr Clin North Am 53:1231–1251PubMedCrossRef
9.
go back to reference Department of Health (2006) The Health Act 2006—code of practice for the prevention and control of healthcare associated infections. Department of Health, London, Ref Type: Generic Department of Health (2006) The Health Act 2006—code of practice for the prevention and control of healthcare associated infections. Department of Health, London, Ref Type: Generic
10.
go back to reference DeRiso AJ, Ladowski JS, Dillon TA, Justice JW, Peterson AC (1996) Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients undergoing heart surgery. Chest 109:1556–1561PubMedCrossRef DeRiso AJ, Ladowski JS, Dillon TA, Justice JW, Peterson AC (1996) Chlorhexidine gluconate 0.12% oral rinse reduces the incidence of total nosocomial respiratory infection and nonprophylactic systemic antibiotic use in patients undergoing heart surgery. Chest 109:1556–1561PubMedCrossRef
11.
go back to reference de Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS, van der Hoeven JG, Pickkers P, Bogaers-Hofman D, van der Meer NJ, Bernards AT, Kuijper EJ, Joore JC, Leverstein-van Hall MA, Bindels AJ, Jansz AR, Wesselink RM, de Jongh BM, Dennesen PJ, van Asselt GJ, te Velde LF, Frenay IH, Kaasjager K, Bosch FH, van Iterson M, Thijsen SF, Kluge GH, Pauw W, de Vries JW, Kaan JA, Arends JP, Aarts LP, Sturm PD, Harinck HI, Voss A, Uijtendaal EV, Blok HE, Thieme Groen ES, Pouw ME, Kalkman CJ, Bonten MJ (2009) Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 360:20–31PubMedCrossRef de Smet AM, Kluytmans JA, Cooper BS, Mascini EM, Benus RF, van der Werf TS, van der Hoeven JG, Pickkers P, Bogaers-Hofman D, van der Meer NJ, Bernards AT, Kuijper EJ, Joore JC, Leverstein-van Hall MA, Bindels AJ, Jansz AR, Wesselink RM, de Jongh BM, Dennesen PJ, van Asselt GJ, te Velde LF, Frenay IH, Kaasjager K, Bosch FH, van Iterson M, Thijsen SF, Kluge GH, Pauw W, de Vries JW, Kaan JA, Arends JP, Aarts LP, Sturm PD, Harinck HI, Voss A, Uijtendaal EV, Blok HE, Thieme Groen ES, Pouw ME, Kalkman CJ, Bonten MJ (2009) Decontamination of the digestive tract and oropharynx in ICU patients. N Engl J Med 360:20–31PubMedCrossRef
12.
go back to reference Drakulovic MB, Torres A, Bauer TT, Nicolas JM, Nogue S, Ferrer M (1999) Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet 354:1851–1858PubMedCrossRef Drakulovic MB, Torres A, Bauer TT, Nicolas JM, Nogue S, Ferrer M (1999) Supine body position as a risk factor for nosocomial pneumonia in mechanically ventilated patients: a randomised trial. Lancet 354:1851–1858PubMedCrossRef
13.
go back to reference du Moulin GC, Paterson DG, Hedley-Whyte J, Lisbon A (1982) Aspiration of gastric bacteria in antacid-treated patients: a frequent cause of postoperative colonisation of the airway. Lancet 1:242–245PubMed du Moulin GC, Paterson DG, Hedley-Whyte J, Lisbon A (1982) Aspiration of gastric bacteria in antacid-treated patients: a frequent cause of postoperative colonisation of the airway. Lancet 1:242–245PubMed
14.
go back to reference Elward AM (2003) Pediatric ventilator-associated pneumonia. Pediatr Infect Dis J 22:445–446PubMed Elward AM (2003) Pediatric ventilator-associated pneumonia. Pediatr Infect Dis J 22:445–446PubMed
15.
go back to reference Elward AM, Warren DK, Fraser VJ (2002) Ventilator-associated pneumonia in pediatric intensive care unit patients: risk factors and outcomes. Pediatrics 109:758–764PubMedCrossRef Elward AM, Warren DK, Fraser VJ (2002) Ventilator-associated pneumonia in pediatric intensive care unit patients: risk factors and outcomes. Pediatrics 109:758–764PubMedCrossRef
16.
go back to reference Fayon MJ, Tucci M, Lacroix J, Farrell CA, Gauthier M, Lafleur L, Nadeau D (1997) Nosocomial pneumonia and tracheitis in a pediatric intensive care unit: a prospective study. Am J Respir Crit Care Med 155:162–169PubMed Fayon MJ, Tucci M, Lacroix J, Farrell CA, Gauthier M, Lafleur L, Nadeau D (1997) Nosocomial pneumonia and tracheitis in a pediatric intensive care unit: a prospective study. Am J Respir Crit Care Med 155:162–169PubMed
17.
go back to reference Feldman C, Kassel M, Cantrell J, Kaka S, Morar R, Goolam MA, Philips JI (1999) The presence and sequence of endotracheal tube colonization in patients undergoing mechanical ventilation. Eur Respir J 13:546–551PubMedCrossRef Feldman C, Kassel M, Cantrell J, Kaka S, Morar R, Goolam MA, Philips JI (1999) The presence and sequence of endotracheal tube colonization in patients undergoing mechanical ventilation. Eur Respir J 13:546–551PubMedCrossRef
18.
go back to reference Fischer JE, Allen P, Fanconi S (2000) Delay of extubation in neonates and children after cardiac surgery: impact of ventilator-associated pneumonia. Intensive Care Med 26:942–949PubMedCrossRef Fischer JE, Allen P, Fanconi S (2000) Delay of extubation in neonates and children after cardiac surgery: impact of ventilator-associated pneumonia. Intensive Care Med 26:942–949PubMedCrossRef
19.
go back to reference Foglia E, Meier MD, Elward A (2007) Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients. Clin Microbiol Rev 20:409–425, tablePubMedCrossRef Foglia E, Meier MD, Elward A (2007) Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients. Clin Microbiol Rev 20:409–425, tablePubMedCrossRef
20.
go back to reference Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM (1988) CDC definitions for nosocomial infections, 1988. Am J Infect Control 16:128–140PubMedCrossRef Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM (1988) CDC definitions for nosocomial infections, 1988. Am J Infect Control 16:128–140PubMedCrossRef
21.
go back to reference Gauvin F, Dassa C, Chaibou M, Proulx F, Farrell CA, Lacroix J (2003) Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods. Pediatr Crit Care Med 4:437–443PubMedCrossRef Gauvin F, Dassa C, Chaibou M, Proulx F, Farrell CA, Lacroix J (2003) Ventilator-associated pneumonia in intubated children: comparison of different diagnostic methods. Pediatr Crit Care Med 4:437–443PubMedCrossRef
22.
go back to reference George DL, Falk PS, Wunderink RG, Leeper KV Jr, Meduri GU, Steere EL, Corbett CE, Mayhall CG (1998) Epidemiology of ventilator-acquired pneumonia based on protected bronchoscopic sampling. Am J Respir Crit Care Med 158:1839–1847PubMed George DL, Falk PS, Wunderink RG, Leeper KV Jr, Meduri GU, Steere EL, Corbett CE, Mayhall CG (1998) Epidemiology of ventilator-acquired pneumonia based on protected bronchoscopic sampling. Am J Respir Crit Care Med 158:1839–1847PubMed
23.
go back to reference Goldstein B, Giroir B, Randolph A (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 6:2–8PubMedCrossRef Goldstein B, Giroir B, Randolph A (2005) International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 6:2–8PubMedCrossRef
24.
go back to reference Hampton DC, Griffith D, Howard A (2005) Evidence-based clinical improvement for mechanically ventilated patients. Rehabil Nurs 30:160–165PubMed Hampton DC, Griffith D, Howard A (2005) Evidence-based clinical improvement for mechanically ventilated patients. Rehabil Nurs 30:160–165PubMed
25.
go back to reference Hess DR (2005) Patient positioning and ventilator-associated pneumonia. Respir Care 50:892–898PubMed Hess DR (2005) Patient positioning and ventilator-associated pneumonia. Respir Care 50:892–898PubMed
26.
go back to reference Kollef MH, Shorr A, Tabak YP, Gupta V, Liu LZ, Johannes RS (2005) Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest 128:3854–3862PubMedCrossRef Kollef MH, Shorr A, Tabak YP, Gupta V, Liu LZ, Johannes RS (2005) Epidemiology and outcomes of health-care-associated pneumonia: results from a large US database of culture-positive pneumonia. Chest 128:3854–3862PubMedCrossRef
27.
go back to reference Kunis KaPK (2003) Ventilator-associated pneumonia in the ICU: its pathophysiology, risk factors and prevention. Am J of Nursing 103(8):64AA–64GG, Ref Type: GenericCrossRef Kunis KaPK (2003) Ventilator-associated pneumonia in the ICU: its pathophysiology, risk factors and prevention. Am J of Nursing 103(8):64AA–64GG, Ref Type: GenericCrossRef
28.
go back to reference Langley JM, Bradley JS (2005) Defining pneumonia in critically ill infants and children. Pediatr Crit Care Med 6:S9–S13PubMedCrossRef Langley JM, Bradley JS (2005) Defining pneumonia in critically ill infants and children. Pediatr Crit Care Med 6:S9–S13PubMedCrossRef
29.
go back to reference Lynn J, Baily MA, Bottrell M, Jennings B, Levine RJ, Davidoff F, Casarett D, Corrigan J, Fox E, Wynia MK, Agich GJ, O’Kane M, Speroff T, Schyve P, Batalden P, Tunis S, Berlinger N, Cronenwett L, Fitzmaurice JM, Dubler NN, James B (2007) The ethics of using quality improvement methods in health care. Ann Intern Med 146:666–673PubMed Lynn J, Baily MA, Bottrell M, Jennings B, Levine RJ, Davidoff F, Casarett D, Corrigan J, Fox E, Wynia MK, Agich GJ, O’Kane M, Speroff T, Schyve P, Batalden P, Tunis S, Berlinger N, Cronenwett L, Fitzmaurice JM, Dubler NN, James B (2007) The ethics of using quality improvement methods in health care. Ann Intern Med 146:666–673PubMed
30.
go back to reference Munro CL, Grap MJ, Elswick RK Jr, McKinney J, Sessler CN, Hummel RS III (2006) Oral health status and development of ventilator-associated pneumonia: a descriptive study. Am J Crit Care 15:453–460PubMed Munro CL, Grap MJ, Elswick RK Jr, McKinney J, Sessler CN, Hummel RS III (2006) Oral health status and development of ventilator-associated pneumonia: a descriptive study. Am J Crit Care 15:453–460PubMed
31.
go back to reference Oostdijk EA, de Smet AM, Blok HE, Thieme Groen ES, van Asselt GJ, Benus RF, Bernards SA, Frenay IH, Jansz AR, de Jongh BM, Kaan JA, Leverstein-van Hall MA, Mascini EM, Pauw W, Sturm PD, Thijsen SF, Kluytmans JA, Bonten MJ (2010) Ecological effects of selective decontamination on resistant gram-negative bacterial colonization. Am J Respir Crit Care Med 181:452–457PubMedCrossRef Oostdijk EA, de Smet AM, Blok HE, Thieme Groen ES, van Asselt GJ, Benus RF, Bernards SA, Frenay IH, Jansz AR, de Jongh BM, Kaan JA, Leverstein-van Hall MA, Mascini EM, Pauw W, Sturm PD, Thijsen SF, Kluytmans JA, Bonten MJ (2010) Ecological effects of selective decontamination on resistant gram-negative bacterial colonization. Am J Respir Crit Care Med 181:452–457PubMedCrossRef
32.
go back to reference Pieracci FM, Barie PS (2007) Strategies in the prevention and management of ventilator-associated pneumonia. Am Surg 73:419–432PubMed Pieracci FM, Barie PS (2007) Strategies in the prevention and management of ventilator-associated pneumonia. Am Surg 73:419–432PubMed
33.
go back to reference Richards MJ, Edwards JR, Culver DH, Gaynes RP (1999) Nosocomial infections in pediatric intensive care units in the United States. National Nosocomial Infections Surveillance System. Pediatrics 103:e39PubMedCrossRef Richards MJ, Edwards JR, Culver DH, Gaynes RP (1999) Nosocomial infections in pediatric intensive care units in the United States. National Nosocomial Infections Surveillance System. Pediatrics 103:e39PubMedCrossRef
34.
go back to reference Richardson A (2009) Minimising central venous catheter-associated bloodstream infections–‘Matching Michigan’ in England. Nurs Crit Care 14:105–106PubMedCrossRef Richardson A (2009) Minimising central venous catheter-associated bloodstream infections–‘Matching Michigan’ in England. Nurs Crit Care 14:105–106PubMedCrossRef
35.
go back to reference Richardson M, Hines S, Dixon G, Highe L, Brierley J (2010) Establishing nurse-led ventilator-associated pneumonia surveillance in paediatric intensive care. J Hosp Infect 75:220–224PubMedCrossRef Richardson M, Hines S, Dixon G, Highe L, Brierley J (2010) Establishing nurse-led ventilator-associated pneumonia surveillance in paediatric intensive care. J Hosp Infect 75:220–224PubMedCrossRef
36.
go back to reference Srinivasan R, Asselin J, Gildengorin G, Wiener-Kronish J, Flori HR (2009) A prospective study of ventilator-associated pneumonia in children. Pediatrics 123:1108–1115PubMedCrossRef Srinivasan R, Asselin J, Gildengorin G, Wiener-Kronish J, Flori HR (2009) A prospective study of ventilator-associated pneumonia in children. Pediatrics 123:1108–1115PubMedCrossRef
37.
go back to reference Stevens B, Lee SK, Law MP, Yamada J (2007) A qualitative examination of changing practice in Canadian neonatal intensive care units. J Eval Clin Pract 13:287–294PubMedCrossRef Stevens B, Lee SK, Law MP, Yamada J (2007) A qualitative examination of changing practice in Canadian neonatal intensive care units. J Eval Clin Pract 13:287–294PubMedCrossRef
38.
go back to reference Torres A, Ewig S, Lode H, Carlet J (2009) Defining, treating and preventing hospital acquired pneumonia: European perspective. Intensive Care Med 35:9–29PubMedCrossRef Torres A, Ewig S, Lode H, Carlet J (2009) Defining, treating and preventing hospital acquired pneumonia: European perspective. Intensive Care Med 35:9–29PubMedCrossRef
39.
go back to reference Wright ML, Romano MJ (2006) Ventilator-associated pneumonia in children. Semin Pediatr Infect Dis 17:58–64PubMedCrossRef Wright ML, Romano MJ (2006) Ventilator-associated pneumonia in children. Semin Pediatr Infect Dis 17:58–64PubMedCrossRef
Metadata
Title
Reducing VAP by instituting a care bundle using improvement methodology in a UK Paediatric Intensive Care Unit
Authors
Joe Brierley
Lorraine Highe
Sarah Hines
Garth Dixon
Publication date
01-02-2012
Publisher
Springer-Verlag
Published in
European Journal of Pediatrics / Issue 2/2012
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-011-1538-y

Other articles of this Issue 2/2012

European Journal of Pediatrics 2/2012 Go to the issue