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Published in: Langenbeck's Archives of Surgery 8/2016

01-12-2016 | ORIGINAL ARTICLE

Enhanced recovery implementation in colorectal surgery—temporary or persistent improvement?

Authors: David Martin, Didier Roulin, Valérie Addor, Catherine Blanc, Nicolas Demartines, Martin Hübner

Published in: Langenbeck's Archives of Surgery | Issue 8/2016

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Abstract

Purpose

Enhanced recovery after surgery (ERAS) implementation has proven to reduce complication rate and length of hospital stay. Little is known about the sustainability of these results over time. The study aim was to assess the application of ERAS pathway over the first 4 years after initial implementation.

Methods

This retrospective study analyzed data collected prospectively from 482 consecutive elective colorectal patients operated in 2011 during the ERAS implementation process (n = 66), and after initial implementation in 2012 (n = 136), 2013 (n = 152), and 2014 (n = 128). Auditing ERAS was appraised from different perspectives: adherence with the ERAS protocol, clinical outcomes, and functional recovery. Patients were compared by year.

Results

The groups were similar in terms of demographics and surgical strategies. Length of stay remained stable at 7 days without significant variation over time (p = 0.741). The 30-day complications and readmission rates were not statistically different (respectively p = 0.068 and p = 0.639). There was also no difference in functional recovery, more particularly, first flatus occurred at day 2 (p = 0.177), pain was adequately controlled with oral analgesics at day 2 (p = 0.111), and patients were mobilized more than 4 h the first postoperative day in more than 60 % of cases (p = 0.343). Overall adherence with the ERAS pathway was 73 % during implementation and, respectively, 73 and 77 % for 2012 and 2013 after initial implementation (p = 0.614). A significant decrease between 2013 (77 %) and 2014 (73 %) was observed (p = 0.032).

Conclusions

Application of the institutional ERAS pathway could be maintained in the first 4 years after implementation leading to sustained improved functional recovery and clinical outcome.
Literature
1.
go back to reference Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M (2014) Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 38(6):1531–1541CrossRefPubMed Greco M, Capretti G, Beretta L, Gemma M, Pecorelli N, Braga M (2014) Enhanced recovery program in colorectal surgery: a meta-analysis of randomized controlled trials. World J Surg 38(6):1531–1541CrossRefPubMed
2.
go back to reference Roulin D, Donadini A, Gander S, Griesser AC, Blanc C, Hubner M, Schafer M, Demartines N (2013) Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 100(8):1108–1114CrossRefPubMed Roulin D, Donadini A, Gander S, Griesser AC, Blanc C, Hubner M, Schafer M, Demartines N (2013) Cost-effectiveness of the implementation of an enhanced recovery protocol for colorectal surgery. Br J Surg 100(8):1108–1114CrossRefPubMed
3.
go back to reference Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, McNaught CE, Macfie J, Liberman AS, Soop M, Hill A, Kennedy RH, Lobo DN, Fearon K, Ljungqvist O (2013) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37(2):259–284CrossRefPubMed Gustafsson UO, Scott MJ, Schwenk W, Demartines N, Roulin D, Francis N, McNaught CE, Macfie J, Liberman AS, Soop M, Hill A, Kennedy RH, Lobo DN, Fearon K, Ljungqvist O (2013) Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37(2):259–284CrossRefPubMed
4.
go back to reference Nygren J, Thacker J, Carli F, Fearon KC, Norderval S, Lobo DN, Ljungqvist O, Soop M, Ramirez J (2013) Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37(2):285–305CrossRefPubMed Nygren J, Thacker J, Carli F, Fearon KC, Norderval S, Lobo DN, Ljungqvist O, Soop M, Ramirez J (2013) Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations. World J Surg 37(2):285–305CrossRefPubMed
5.
go back to reference Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146(5):571–577CrossRefPubMed Gustafsson UO, Hausel J, Thorell A, Ljungqvist O, Soop M, Nygren J (2011) Adherence to the enhanced recovery after surgery protocol and outcomes after colorectal cancer surgery. Arch Surg 146(5):571–577CrossRefPubMed
6.
go back to reference The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an International Registry (2015). Ann Surg 261(6):1153–1159. The impact of enhanced recovery protocol compliance on elective colorectal cancer resection: results from an International Registry (2015). Ann Surg 261(6):1153–1159.
7.
go back to reference Gillissen F, Hoff C, Maessen JM, Winkens B, Teeuwen JH, von Meyenfeldt MF, Dejong CH (2013) Structured synchronous implementation of an enhanced recovery program in elective colonic surgery in 33 hospitals in the Netherlands. World J Surg 37(5):1082–1093CrossRefPubMed Gillissen F, Hoff C, Maessen JM, Winkens B, Teeuwen JH, von Meyenfeldt MF, Dejong CH (2013) Structured synchronous implementation of an enhanced recovery program in elective colonic surgery in 33 hospitals in the Netherlands. World J Surg 37(5):1082–1093CrossRefPubMed
8.
go back to reference Miller TE, Thacker JK, White WD, Mantyh C, Migaly J, Jin J, Roche AM, Eisenstein EL, Edwards R, Anstrom KJ, Moon RE, Gan TJ (2014) Reduced length of hospital stay in colorectal surgery after implementation of an enhanced recovery protocol. Anesth Analg 118(5):1052–1061CrossRefPubMed Miller TE, Thacker JK, White WD, Mantyh C, Migaly J, Jin J, Roche AM, Eisenstein EL, Edwards R, Anstrom KJ, Moon RE, Gan TJ (2014) Reduced length of hospital stay in colorectal surgery after implementation of an enhanced recovery protocol. Anesth Analg 118(5):1052–1061CrossRefPubMed
9.
go back to reference Gillissen F, Ament SM, Maessen JM, Dejong CH, Dirksen CD, van der Weijden T, von Meyenfeldt MF (2014) Sustainability of an enhanced recovery after surgery program (ERAS) in colonic surgery. World J Surg Gillissen F, Ament SM, Maessen JM, Dejong CH, Dirksen CD, van der Weijden T, von Meyenfeldt MF (2014) Sustainability of an enhanced recovery after surgery program (ERAS) in colonic surgery. World J Surg
10.
go back to reference Roulin D, Blanc C, Muradbegovic M, Hahnloser D, Demartines N, Hubner M (2014) Enhanced recovery pathway for urgent colectomy. World J Surg 38(8):2153–2159CrossRefPubMed Roulin D, Blanc C, Muradbegovic M, Hahnloser D, Demartines N, Hubner M (2014) Enhanced recovery pathway for urgent colectomy. World J Surg 38(8):2153–2159CrossRefPubMed
11.
go back to reference Maessen J, Dejong CH, Hausel J, Nygren J, Lassen K, Andersen J, Kessels AG, Revhaug A, Kehlet H, Ljungqvist O, Fearon KC, von Meyenfeldt MF (2007) A protocol is not enough to implement an enhanced recovery programme for colorectal resection. Br J Surg 94(2):224–231CrossRefPubMed Maessen J, Dejong CH, Hausel J, Nygren J, Lassen K, Andersen J, Kessels AG, Revhaug A, Kehlet H, Ljungqvist O, Fearon KC, von Meyenfeldt MF (2007) A protocol is not enough to implement an enhanced recovery programme for colorectal resection. Br J Surg 94(2):224–231CrossRefPubMed
12.
go back to reference Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213CrossRefPubMedPubMedCentral Dindo D, Demartines N, Clavien PA (2004) Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg 240(2):205–213CrossRefPubMedPubMedCentral
13.
go back to reference Pedziwiatr M, Kisialeuski M, Wierdak M, Stanek M, Natkaniec M, Matlok M, Major P, Malczak P, Budzynski A (2015) Early implementation of Enhanced Recovery After Surgery (ERAS®) protocol—compliance improves outcomes: a prospective cohort study. Int J Surg 21:75–81CrossRefPubMed Pedziwiatr M, Kisialeuski M, Wierdak M, Stanek M, Natkaniec M, Matlok M, Major P, Malczak P, Budzynski A (2015) Early implementation of Enhanced Recovery After Surgery (ERAS®) protocol—compliance improves outcomes: a prospective cohort study. Int J Surg 21:75–81CrossRefPubMed
14.
go back to reference Hendry PO, Hausel J, Nygren J, Lassen K, Dejong CH, Ljungqvist O, Fearon KC (2009) Determinants of outcome after colorectal resection within an enhanced recovery programme. Br J Surg 96(2):197–205CrossRefPubMed Hendry PO, Hausel J, Nygren J, Lassen K, Dejong CH, Ljungqvist O, Fearon KC (2009) Determinants of outcome after colorectal resection within an enhanced recovery programme. Br J Surg 96(2):197–205CrossRefPubMed
15.
go back to reference Alcantara-Moral M, Serra-Aracil X, Gil-Egea MJ, Frasson M, Flor-Lorente B, Garcia-Granero E (2014) Observational cross-sectional study of compliance with the fast track protocol in elective surgery for colon cancer in Spain. Int J Color Dis 29(4):477–483CrossRef Alcantara-Moral M, Serra-Aracil X, Gil-Egea MJ, Frasson M, Flor-Lorente B, Garcia-Granero E (2014) Observational cross-sectional study of compliance with the fast track protocol in elective surgery for colon cancer in Spain. Int J Color Dis 29(4):477–483CrossRef
16.
go back to reference Bakker N, Cakir H, Doodeman HJ, Houdijk AP (2015) Eight years of experience with enhanced recovery after surgery in patients with colon cancer: impact of measures to improve adherence. Surgery 157 (6):1130–1136. Bakker N, Cakir H, Doodeman HJ, Houdijk AP (2015) Eight years of experience with enhanced recovery after surgery in patients with colon cancer: impact of measures to improve adherence. Surgery 157 (6):1130–1136.
17.
go back to reference Gillissen F, Ament SM, Maessen JM, Dejong CH, Dirksen CD, van der Weijden T, von Meyenfeldt MF (2015) Sustainability of an enhanced recovery after surgery program (ERAS) in colonic surgery. World J Surg 39(2):526–533CrossRefPubMed Gillissen F, Ament SM, Maessen JM, Dejong CH, Dirksen CD, van der Weijden T, von Meyenfeldt MF (2015) Sustainability of an enhanced recovery after surgery program (ERAS) in colonic surgery. World J Surg 39(2):526–533CrossRefPubMed
18.
go back to reference Lyon A, Solomon MJ, Harrison JD (2014) A qualitative study assessing the barriers to implementation of enhanced recovery after surgery. World J Surg 38(6):1374–1380CrossRefPubMed Lyon A, Solomon MJ, Harrison JD (2014) A qualitative study assessing the barriers to implementation of enhanced recovery after surgery. World J Surg 38(6):1374–1380CrossRefPubMed
19.
go back to reference Ljungqvist O (2015) Sustainability after structured implementation of ERAS protocols. World J Surg 39(2):534–535CrossRefPubMed Ljungqvist O (2015) Sustainability after structured implementation of ERAS protocols. World J Surg 39(2):534–535CrossRefPubMed
20.
go back to reference Cakir H, van Stijn MF, Lopes Cardozo AM, Langenhorst BL, Schreurs WH, van der Ploeg TJ, Bemelman WA, Houdijk AP (2013) Adherence to enhanced recovery after surgery and length of stay after colonic resection. Color Dis 15 (8):1019–1025. Cakir H, van Stijn MF, Lopes Cardozo AM, Langenhorst BL, Schreurs WH, van der Ploeg TJ, Bemelman WA, Houdijk AP (2013) Adherence to enhanced recovery after surgery and length of stay after colonic resection. Color Dis 15 (8):1019–1025.
21.
go back to reference Smart NJ, White P, Allison AS, Ockrim JB, Kennedy RH, Francis NK (2012) Deviation and failure of enhanced recovery after surgery following laparoscopic colorectal surgery: early prediction model. Color Dis 14(10):e727–e734CrossRef Smart NJ, White P, Allison AS, Ockrim JB, Kennedy RH, Francis NK (2012) Deviation and failure of enhanced recovery after surgery following laparoscopic colorectal surgery: early prediction model. Color Dis 14(10):e727–e734CrossRef
Metadata
Title
Enhanced recovery implementation in colorectal surgery—temporary or persistent improvement?
Authors
David Martin
Didier Roulin
Valérie Addor
Catherine Blanc
Nicolas Demartines
Martin Hübner
Publication date
01-12-2016
Publisher
Springer Berlin Heidelberg
Published in
Langenbeck's Archives of Surgery / Issue 8/2016
Print ISSN: 1435-2443
Electronic ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-016-1518-9

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