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Open Access 01-05-2008 | Original Article

Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations

Authors: Lutz Roewer, Sascha Willuweit, Carmen Krüger, Marion Nagy, Sergey Rychkov, Irina Morozowa, Oksana Naumova, Yuriy Schneider, Olga Zhukova, Mark Stoneking, Ivan Nasidze

Published in: International Journal of Legal Medicine | Issue 3/2008

Abstract

A total of 17 Y-specific STR loci were studied in 12 districts of the European part of Russia aiming to ascertain the amount of substructure required for the construction of a representative regional database. All groups exhibited high haplotype diversities but low inter-population variance as measured by an analysis of molecular variance. However, when Western Russia is taken as a whole, the genetic distances to the neighbouring populations were significant. Whereas gradual change in the Y chromosome pool exists between Russia and the Slavic-speaking populations to the West, remarkable discontinuities were observed with neighbouring populations in the East, North and South.

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Kayser M, Krawczak M, Excoffier L et al (2001) An extensive analysis of Y-chromosomal microsatellite haplotypes in globally dispersed human populations. Am J Hum Genet 68(4):990–1018PubMedCrossRef

Roewer L, Croucher PJ, Willuweit S et al (2005) Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Hum Genet 116(4):279–291PubMedCrossRef

Willuweit S, Roewer L (2007) Y Chromosome Haplotype Reference Database (YHRD): update. Forensic Sci Int Genetics 1(2):83–87CrossRef

Gusmao L, Butler JM, Carracedo A et al (2006) DNA Commission of the International Society of Forensic Genetics. Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Int J Legal Med 120(4):191–200PubMedCrossRef

Fechner A, Quinque D, Rychkov S et al (2007) Boundaries and clines in the West Eurasian Y-chromosome landscape: insights from the European part of Russia. Am J Phys Anthropol (in press)

Mulero JJ, Chang CW, Calandro LM, Green RL, Li Y, Johnson CL, Hennessy LK (2006) Development and validation of the AmpFlSTR Yfiler PCR amplification kit: a male specific, single amplification 17 Y-STR multiplex system. J Forensic Sci 51:64–75PubMedCrossRef

Excoffier L, Smouse PE, Quattro JM (1992) Analysis of molecular variance inferred from metric distances among DNA haplotypes: Application to human mitochondrial DNA restriction data. Genetics 131:479–491PubMed

Roewer L, Kayser M, Dieltjes P, Nagy M, Bakker E, Krawczak M, de Knijff P (1996) Analysis of molecular variance (AMOVA) of Y-chromosome-specific microsatellites in two closely related human populations. Hum Mol Genet 5(7):1029–1033PubMedCrossRef

Rebala K, Mikulich AI, Tsybovsky IS, Sivakova D, Dzupinkova Z, Szczerkowska- Dobosz A, Szczerkowska Z (2007) Y-STR variation among Slavs: evidence for the Slavic homeland in the middle Dnieper basin. J Hum Genet 52(5):406–414PubMedCrossRef

10.

Nasidze I, Schädlich H, Stoneking M (2003) Haplotypes from the Caucasus, Turkey and Iran for nine Y-STR loci. Forensic Sci Int 137:85–93PubMedCrossRef

11.

Lessig R, Edelmann J, Krawczak M (2001) Population genetics of Y-chromosomal microsatellites in Baltic males. Forensic Sci Int 118:153–157PubMedCrossRef

12.

Hedman M, Pimenoff V, Lukka M, Sistonen P, Sajantila A (2004) Analysis of 16 Y STR loci in the Finnish population reveals a local reduction in the diversity of male lineages. Forensic Sci Int 142(1):37–43PubMedCrossRef

13.

Ploski R, Wozniak M, Pawlowski R et al (2002) Homogeneity and distinctiveness of Polish paternal lineages revealed by Y chromosome microsatellite haplotype analysis. Hum Genet 110:592–600PubMedCrossRef

14.

Pawlowski R, Dettlaff-Kakol A (2003) Population data of nine Y-chromosomal STR loci in northern Poland. Forensic Sci Int 131(2–3):209–213PubMedCrossRef

15.

Pepinski W, Niemcunowicz-Janica A, Ptaszynska-Sarosiek I, Skawronska M, Koc-Zorawska E, Janica J, Soltyszewski I (2004) Population genetics of Y-chromosome STRs in a population of Podlasie, northeastern Poland. Forensic Sci Int 144(1):77–82PubMedCrossRef

16.

Pakendorf B, Novgorodov IN, Osakovskij VL, Danilova AP, Protodjakonov AP, Stoneking M (2006) Investigating the effects of prehistoric migrations in Siberia: genetic variation and the origins of Yakuts. Hum Genet 120(3):334–353PubMedCrossRef

17.

Pakendorf B, Novgorodov IN, Osakovskij VL, Stoneking M (2007) Mating patterns amongst Siberian reindeer herders: inferences from mtDNA and Y-chromosomal analyses. Am J Phys Anthropol 133:1013–1027PubMedCrossRef

18.

Kravchenko SA, Slominskii PA, Bets LA, Stepanova AV, Mikulich AI, Limborskaya SA, Livshits LA (2002) Polymorphism of STR Loci of the Y chromosome in three populations of Eastern Slavs from Belarus, Russia and Ukraine. Rus J Genet 38(1):80–86CrossRef

19.

Kruskal JB (1964) Multidimensional scaling by optimizing goodness of fit to a nonmetric hypothesis. Psychometrika 29:1–27CrossRef

20.

Roewer L, Kayser M, de Knijff P et al (2000) A new method for the evaluation of matches in non-recombining genomes: application to Y-chromosomal short tandem repeat (STR) haplotypes in European males. For Sci Int 114(1):31–43

Title: Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations
Authors: Lutz Roewer
Sascha Willuweit
Carmen Krüger
Marion Nagy
Sergey Rychkov
Irina Morozowa
Oksana Naumova
Yuriy Schneider
Olga Zhukova
Mark Stoneking
Ivan Nasidze
Publication date: 01-05-2008
Publisher: Springer-Verlag
Published in: International Journal of Legal Medicine / Issue 3/2008
Print ISSN: 0937-9827
Electronic ISSN: 1437-1596
DOI: https://doi.org/10.1007/s00414-007-0222-2

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Analysis of Y chromosome STR haplotypes in the European part of Russia reveals high diversities but non-significant genetic distances between populations

Abstract

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Abstract

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