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Published in: Lung 2/2018

01-04-2018 | State of the Art Review

Recent Advances in Bronchopulmonary Dysplasia: Pathophysiology, Prevention, and Treatment

Authors: Jung S. Hwang, Virender K. Rehan

Published in: Lung | Issue 2/2018

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Abstract

Bronchopulmonary dysplasia (BPD) is potentially one of the most devastating conditions in premature infants with longstanding consequences involving multiple organ systems including adverse effects on pulmonary function and neurodevelopmental outcome. Here we review recent studies in the field to summarize the progress made in understanding in the pathophysiology, prognosis, prevention, and treatment of BPD in the last decade. The work reviewed includes the progress in understanding its pathobiology, genomic studies, ventilatory strategies, outcomes, and therapeutic interventions. We expect that this review will help guide clinicians to treat premature infants at risk for BPD better and lead researchers to initiate further studies in the field.
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Metadata
Title
Recent Advances in Bronchopulmonary Dysplasia: Pathophysiology, Prevention, and Treatment
Authors
Jung S. Hwang
Virender K. Rehan
Publication date
01-04-2018
Publisher
Springer US
Published in
Lung / Issue 2/2018
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-018-0084-z

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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