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Published in: European Archives of Oto-Rhino-Laryngology 1/2008

01-01-2008 | Review Article

Supraglottic laryngectomy: analysis of 267 cases

Authors: Maria Agustina Sevilla, Juan Pablo Rodrigo, José Luis Llorente, Rubén Cabanillas, Fernando López, Carlos Suárez

Published in: European Archives of Oto-Rhino-Laryngology | Issue 1/2008

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Abstract

Horizontal supraglottic laryngectomy (HSL) allows the preservation of a functioning larynx and avoids permanent tracheotomy. In this retrospective study we report our experience with HSL and describe the functional and oncological results of the procedure. A total of 267 previously untreated patients with squamous cell carcinoma of the supraglottis underwent a supraglottic laryngectomy at our Department from January 1978 to May 2002. The main outcome measures were: local and regional control, disease-specific survival and laryngeal preservation rate. The overall recurrence rate was 29% (78/267). The local recurrence rate was 8% (22 patients) and the regional recurrence rate was 17% (45 patients). The 5-year disease-specific survival rate was 73%. The 5-year laryngeal preservation rate was 82%. Multivariate analysis showed two parameters that were independent predictors of a reduced disease specific survival: cervical lymph node metastases of class N3 (P = 0.0003) and primary tumour classified as T4 (P = 0.004). HSL provided, in our experience, an optimal locoregional oncological control for laryngeal preservation.
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Metadata
Title
Supraglottic laryngectomy: analysis of 267 cases
Authors
Maria Agustina Sevilla
Juan Pablo Rodrigo
José Luis Llorente
Rubén Cabanillas
Fernando López
Carlos Suárez
Publication date
01-01-2008
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 1/2008
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-007-0415-9

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