Skip to main content
Top
Published in: European Archives of Oto-Rhino-Laryngology 1/2008

01-01-2008 | Otology

Usefulness of CT scans in malignant external otitis: effective tool for the diagnosis, but of limited value in predicting outcome

Authors: Holger Sudhoff, Sandeep Rajagopal, Navin Mani, Ioannis Moumoulidis, Patrick R. Axon, David Moffat

Published in: European Archives of Oto-Rhino-Laryngology | Issue 1/2008

Login to get access

Abstract

Computerized tomography (CT) scanning is a well recognised tool for the diagnosis of malignant external otitis. To investigate the degree of correlation between CT findings scan and the patients clinical status focusing on a subgroup of patients with cranial nerve palsies. Diagnosis of malignant external otitis was confirmed in 23 patients (average age 71 years, age range 39–87) based on criteria of severe pain, otitis externa refractory to conventional treatments and possibly diabetes mellitus and pseudomonas detection. CT was performed on 23 of these patients. Results from these scans were analysed and correlated with patient clinical status. Retrospective analysis of CT images and medical notes were used for data analysis.The CT scans of all 23 patients showed evidence of involvement of disease outside the external auditory canal, confirming the diagnosis. Sixteen out of 23 patients (70%) demonstrated evidence of bone erosion. Four of the 16 showed involvement of the petrous apex. From our subset of ten patients with cranial nerve involvement, eight demonstrated evidence of bone erosion and two showed mastoid and middle ear involvement without bone erosion. All four patients with petrous apical involvement presented with cranial nerve palsies (two lower cranial nerve palsies, one seventh nerve palsy and one combined lower and seventh nerve palsy). CT scanning was found to be a fast and economical tool in the initial assessment of patients with malignant external otitis. Petrous apex involvement was constantly associated with cranial nerve palsies, usually the lower cranial nerves. CT findings of temporal bone in itself however, were not closely correlated to the clinical outcome of the patients.
Literature
1.
go back to reference Schuknecht HF (1993) Pathology of the ear, 2nd edn. Lea & Febiger, Philadelphia, pp 220–223 Schuknecht HF (1993) Pathology of the ear, 2nd edn. Lea & Febiger, Philadelphia, pp 220–223
2.
go back to reference Sudhoff H, Linthicum FH Jr (2003) Malignant external otitis: temporal bone histopathology case of the month. Otol Neurotol 24:346–347PubMedCrossRef Sudhoff H, Linthicum FH Jr (2003) Malignant external otitis: temporal bone histopathology case of the month. Otol Neurotol 24:346–347PubMedCrossRef
3.
go back to reference Meltzer PE, Kelemen G (1959) Pyocyaneous osteomyelitis of the temporal bone, mandible and zygoma. Laryngoscope 69:1300–1316CrossRef Meltzer PE, Kelemen G (1959) Pyocyaneous osteomyelitis of the temporal bone, mandible and zygoma. Laryngoscope 69:1300–1316CrossRef
5.
go back to reference Slattery WH 3rd, Brackmann DE (1996) Skull base osteomyelitis. Malignant external otitis. Otolaryngol Clin North Am 29:795–806PubMed Slattery WH 3rd, Brackmann DE (1996) Skull base osteomyelitis. Malignant external otitis. Otolaryngol Clin North Am 29:795–806PubMed
6.
go back to reference Rowlands RG, Lekakis GK, Hinton AE (2002) Masked pseudomonal skull base osteomyelitis presenting with bilateral Xth cranial nerve palsy. J Laryngol Otol 116:556–558PubMedCrossRef Rowlands RG, Lekakis GK, Hinton AE (2002) Masked pseudomonal skull base osteomyelitis presenting with bilateral Xth cranial nerve palsy. J Laryngol Otol 116:556–558PubMedCrossRef
7.
go back to reference Chole RA, Sudhoff H (2005) Acute and chronic otitis media and mastoiditis. In: Charles Cummings MD, Paul Flint MD, Lee Harker MD, Bruce Haughey MD, Mark Richardson MD, Thomas Robbins MD, David Schuller MD, Regan Thomas MD (eds) Otolaryngology, head and neck surgery, 4th edn. Elsevier, Mosby, pp 2988–3012 Chole RA, Sudhoff H (2005) Acute and chronic otitis media and mastoiditis. In: Charles Cummings MD, Paul Flint MD, Lee Harker MD, Bruce Haughey MD, Mark Richardson MD, Thomas Robbins MD, David Schuller MD, Regan Thomas MD (eds) Otolaryngology, head and neck surgery, 4th edn. Elsevier, Mosby, pp 2988–3012
8.
go back to reference Levenson MJ, Parisier SC, Dolitsky J, Bindra G (1991) Ciprofloxacin: drug of choice in the treatment of malignant external otitis (MEO). Laryngoscope 101:821–824PubMedCrossRef Levenson MJ, Parisier SC, Dolitsky J, Bindra G (1991) Ciprofloxacin: drug of choice in the treatment of malignant external otitis (MEO). Laryngoscope 101:821–824PubMedCrossRef
9.
go back to reference Amorosa L, Modugno GC, Pirodda A (1996) Malignant external otitis: review and personal experience. Acta Otolaryngol Suppl 521:3–16PubMed Amorosa L, Modugno GC, Pirodda A (1996) Malignant external otitis: review and personal experience. Acta Otolaryngol Suppl 521:3–16PubMed
10.
go back to reference House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol Head Neck Surg 93:146–147PubMed House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol Head Neck Surg 93:146–147PubMed
11.
go back to reference Cohen D, Friedman P (1987) The diagnostic criteria of malignant external otitis. J Laryngol Ool 101:216–221 Cohen D, Friedman P (1987) The diagnostic criteria of malignant external otitis. J Laryngol Ool 101:216–221
12.
go back to reference Corey JP, Levandowski RA, Panwalker AP (1985) Prognostic implications of therapy for necrotizing external otitis. Am J otol 6:353–358PubMed Corey JP, Levandowski RA, Panwalker AP (1985) Prognostic implications of therapy for necrotizing external otitis. Am J otol 6:353–358PubMed
13.
go back to reference Handzel O, Halperin D (2003) Necrotising (malignant) external otitis. Amm Fam Physician 68:309–312 Handzel O, Halperin D (2003) Necrotising (malignant) external otitis. Amm Fam Physician 68:309–312
14.
go back to reference Rubin Grandis J, Branstetter BF 4th, Yu VL (2004) The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations. Lancet Infect Dis 4:34–39PubMedCrossRef Rubin Grandis J, Branstetter BF 4th, Yu VL (2004) The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations. Lancet Infect Dis 4:34–39PubMedCrossRef
15.
go back to reference Sreepada GS, Kwartler JA (2003) Skull base osteomyelitis secondary to malignant otitis externa. Curr Opin Otolaryngol Head Neck Surg 11:316–323PubMedCrossRef Sreepada GS, Kwartler JA (2003) Skull base osteomyelitis secondary to malignant otitis externa. Curr Opin Otolaryngol Head Neck Surg 11:316–323PubMedCrossRef
16.
go back to reference Rubin J, Yu YL (1988) Malignant external otitis: insights into pathogenesis, clinical manifestations, diagnosis, and therapy. Am J Med 85:391–398PubMedCrossRef Rubin J, Yu YL (1988) Malignant external otitis: insights into pathogenesis, clinical manifestations, diagnosis, and therapy. Am J Med 85:391–398PubMedCrossRef
17.
go back to reference Berenholz L, Katzenell U, Harell M (2002) Evolving resistant pseudomonas to ciprofloxacin in malignant otitis externa. Laryngoscope 112:1619–1622PubMedCrossRef Berenholz L, Katzenell U, Harell M (2002) Evolving resistant pseudomonas to ciprofloxacin in malignant otitis externa. Laryngoscope 112:1619–1622PubMedCrossRef
18.
go back to reference Grossman RF (1997) The role of fluoroquinolones in respiratory tract infections. J Antimicrob Chemother 40(suppl A):59–62PubMedCrossRef Grossman RF (1997) The role of fluoroquinolones in respiratory tract infections. J Antimicrob Chemother 40(suppl A):59–62PubMedCrossRef
Metadata
Title
Usefulness of CT scans in malignant external otitis: effective tool for the diagnosis, but of limited value in predicting outcome
Authors
Holger Sudhoff
Sandeep Rajagopal
Navin Mani
Ioannis Moumoulidis
Patrick R. Axon
David Moffat
Publication date
01-01-2008
Publisher
Springer-Verlag
Published in
European Archives of Oto-Rhino-Laryngology / Issue 1/2008
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI
https://doi.org/10.1007/s00405-007-0416-8

Other articles of this Issue 1/2008

European Archives of Oto-Rhino-Laryngology 1/2008 Go to the issue