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Archives of Gynecology and Obstetrics

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01-05-2012 | Gynecologic Oncology

Uterine artery embolization versus surgery for symptomatic uterine fibroids: a randomized controlled trial and a meta-analysis of the literature

Authors: Feng Jun, Liu Yamin, Xiao Xinli, Liu Zhe, Zhang Min, Zhang Bo, Gou Wenli

Published in: Archives of Gynecology and Obstetrics | Issue 5/2012

Abstract

Purpose

The aim of our study was to compare the efficacy and safety of uterine artery embolization (UAE) for symptomatic uterine fibroids with surgery.

Methods

Both a randomized, controlled trial and meta-analysis of existing studies were performed.

Results

Patients were randomly assigned in a 1:1 ratio to undergo either UAE or surgery with 63 patients undergoing UAE and 64 undergoing surgery. A meta-analysis of existing studies was also performed.There were significant improvements in UAE groups in most components of quality of life assessment at 6 months. Besides, the UAE group had a shorter hospital stay (P < 0.01) and a shorter recovery time (P < 0.01) compared with the surgical group. During the follow-up, there were no difference in complications incidence (58 vs. 65%, P > 0.05), but the UAE group had less major complications (0 vs. 6%, P < 0.05). Meta-analysis of existing studies including those from the current study, further suggested that UAE group had a shorter hospital stay, a shorter recovery time and less major complications than the surgical group.

Conclusions

Compared with surgery, UAE has a shorter hospital stay, a shorter recovery time, and less major complications. More studies in the future need to done to evaluate its long-term effects and impact on fertility.

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Title: Uterine artery embolization versus surgery for symptomatic uterine fibroids: a randomized controlled trial and a meta-analysis of the literature
Authors: Feng Jun
Liu Yamin
Xiao Xinli
Liu Zhe
Zhang Min
Zhang Bo
Gou Wenli
Publication date: 01-05-2012
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 5/2012
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-011-2065-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Uterine artery embolization versus surgery for symptomatic uterine fibroids: a randomized controlled trial and a meta-analysis of the literature

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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