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24-07-2023 | Vitiligo | RESEARCH LETTER

Lack of diversity in vitiligo clinical trials: a cross-sectional analysis

Authors: Loren E. Hernandez, Samantha Verling, Keyvan Nouri

Published in: Archives of Dermatological Research | Issue 9/2023

Excerpt

Vitiligo is a chronic, autoimmune depigmenting disorder of the skin with an estimated population-based prevalence between 0.76 and 1.11% within the United States (U.S.) [1]. As compared to the general population, vitiligo patients experience a greater prevalence of psychiatric comorbidities such as depression and anxiety. Vitiligo can be particularly distressing for individuals with skin of color, as the depigmented patches are often more noticeable. Moreover, it has been shown that the degree of depression in vitiligo patients can be attributed to cultural perceptions of skin dyspigmentation and base skin color [2]. …

Gandhi K, Ezzedine K, Anastassopoulos KP, Patel R, Sikirica V, Daniel SR, Napatalung L, Yamaguchi Y, Baik R, Pandya AG (2022) Prevalence of vitiligo among adults in the United States. JAMA Dermatol 158(1):43–50. https://doi.org/10.1001/jamadermatol.2021.4724. (PMID:34787670;PMCID:PMC8600454)CrossRefPubMed

Alghamdi KM, Moussa NA, Mandil A et al (2012) Public perceptions and attitudes toward vitiligo. J Cutan Med Surg 16(5):334–340. https://doi.org/10.1177/120347541201600510CrossRefPubMed

Vespa J, Medina L, Armstrong DM. Demographic Turning Points for the United States: Population Projections for 2020 to 2060. U.S. Census Bureau. 2020 Feb:25–1144.

United States Census Bureau. Quick Facts. Retrieved from: https://www.census.gov/quickfacts/fact/table/US/PST045222. Accessed 1 Apr 2023

Title: Lack of diversity in vitiligo clinical trials: a cross-sectional analysis
Authors: Loren E. Hernandez
Samantha Verling
Keyvan Nouri
Publication date: 24-07-2023
Publisher: Springer Berlin Heidelberg
Keyword: Vitiligo
Published in: Archives of Dermatological Research / Issue 9/2023
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI: https://doi.org/10.1007/s00403-023-02678-3

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Lack of diversity in vitiligo clinical trials: a cross-sectional analysis

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