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Published in: Archives of Dermatological Research 3/2023

21-09-2022 | Skin Cancer | Review

Flavonoids and their therapeutic applications in skin diseases

Authors: Emily Z. Ma, Amor Khachemoune

Published in: Archives of Dermatological Research | Issue 3/2023

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Abstract

Flavonoids are a class of plant polyphenols found in a variety of fruits, vegetables, teas, and flowers. These compounds are present in many common dietary sources, such as green tea, wine, pomegranates, and turmeric, and possess a broad spectrum of biological activity due to their unique chemical structure. Flavonoids exhibit antioxidant, anti-inflammatory, antiviral, and anticarcinogenic properties that have been widely studied as potential therapeutics for diseases ranging from Alzheimer’s disease to liver disease. There is currently significant research into therapeutic benefits of flavonoids in various skin conditions as these compounds have been shown to absorb ultraviolet radiation and modulate cancer and inflammation signaling pathways. This review discusses the current research in the application of flavonoids in skin diseases (e.g., prevention of premature photoaging, prevention and treatment of skin cancer, and promotion of skin wound healing) and their proposed mechanisms to provide a basis for future basic and translational research of flavonoids as potential drugs in the prevention and treatment of skin disorders.
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Metadata
Title
Flavonoids and their therapeutic applications in skin diseases
Authors
Emily Z. Ma
Amor Khachemoune
Publication date
21-09-2022
Publisher
Springer Berlin Heidelberg
Keyword
Skin Cancer
Published in
Archives of Dermatological Research / Issue 3/2023
Print ISSN: 0340-3696
Electronic ISSN: 1432-069X
DOI
https://doi.org/10.1007/s00403-022-02395-3

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