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Open Access 20-09-2022 | Cholangiocarcinoma | Original Article

Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts

Authors: Yunosuke Kawaguchi, Keita Terui, Shugo Komatsu, Mitsuyuki Nakata, Ryohei Shibata, Hiroko Yoshizawa, Tomoya Hirokawa, Erika Nakatani, Tomoro Hishiki

Published in: Pediatric Surgery International | Issue 12/2022

Abstract

Purpose

Hepatobiliary scintigraphy is a minimally invasive imaging method that evaluates bile flow dynamics. At our hospital, it has been performed for postoperative evaluation of patients with choledochal cysts (CC). This study evaluated the usefulness of biliary scintigraphy for predicting late complications in patients with CCs.

Methods

The study included pediatric patients with CC who underwent surgery at Chiba University Hospital from 1978 to 2020, followed by postoperative biliary scintigraphy and subsequent radiologic evaluation. The patients were divided into two groups according to the presence or absence of “biliary cholestasis” on biliary scintigraphy.

Results

The study included 108 patients, with a median age at surgery of 2 years and 11 months. The median follow-up period was 5203 days, with 11 hepatolithiasis cases and 8 cholangitis cases. No patients had cholangiocarcinoma. Twelve patients were considered to have “cholestasis” following biliary scintigraphy evaluation. There was no significant difference in the occurrence of hepatolithiasis between the cholestasis and non-cholestasis groups (p = 0.47), but cholangitis was significantly more common in the cholestasis group (p = 0.016).

Conclusion

Biliary cholestasis on postoperative hepatobiliary scintigraphy was a risk factor for cholangitis in patients with CCs. These particular patients should be monitored carefully.

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Title: Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts
Authors: Yunosuke Kawaguchi
Keita Terui
Shugo Komatsu
Mitsuyuki Nakata
Ryohei Shibata
Hiroko Yoshizawa
Tomoya Hirokawa
Erika Nakatani
Tomoro Hishiki
Publication date: 20-09-2022
Publisher: Springer Berlin Heidelberg
Keywords: Cholangiocarcinoma
Cholangiocarcinoma
Cholangitis
Scintigraphy
Published in: Pediatric Surgery International / Issue 12/2022
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-022-05241-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Usefulness of hepatobiliary scintigraphy for predicting late complications in patients with choledochal cysts

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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