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Pediatric Surgery International
Published in: Pediatric Surgery International 5/2016

01-05-2016 | Review Article

Pediatric lymphatic malformations: evolving understanding and therapeutic options

Authors: Ann M. Defnet, Naina Bagrodia, Sonia L. Hernandez, Natalie Gwilliam, Jessica J. Kandel

Published in: Pediatric Surgery International | Issue 5/2016

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Abstract

Multimodal treatment of lymphatic malformations continues to expand as new information about the biology and genetics of these lesions is discovered, along with knowledge gained from clinical practice. A patient-centered approach, ideally provided by a multidisciplinary medical and surgical team, should guide timing and modality of treatment. Current treatment options include observation, surgery, sclerotherapy, radiofrequency ablation, and laser therapy. New medical and surgical therapies are emerging, and include sildenafil, propranolol, sirolimus, and vascularized lymph node transfer. The primary focus of management is to support and optimize these patients’ quality of life. Researchers continue to study lymphatic malformations with the goal of increasing therapeutic options and developing effective clinical pathways for these complicated lesions.
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Metadata
Title
Pediatric lymphatic malformations: evolving understanding and therapeutic options
Authors
Ann M. Defnet
Naina Bagrodia
Sonia L. Hernandez
Natalie Gwilliam
Jessica J. Kandel
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Surgery International / Issue 5/2016
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI
https://doi.org/10.1007/s00383-016-3867-4

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