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Pediatric Surgery International

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01-05-2010 | Original Article

LigaSure™ compared with ligatures and endoclips in experimental appendectomy: how safe is it?

Authors: Levent Elemen, Yusufhan Yazir, Melih Tugay, Alper Akay, Seval Aydin, Karolin Yanar, Süreyya Ceylan

Published in: Pediatric Surgery International | Issue 5/2010

Abstract

Purpose

The present study aims to compare strength, healing, and inflammation of appendiceal stumps closed by LigaSure Precise™ (Valleylab, Boulder, CO, USA) device, ligatures using polyglactin 910 (Vicryl, Ethicon, Edinburgh, UK) and endoclips (Ligaclip ERCA, Ethicon, OH, USA), and operation time (OT) in experimental appendectomy.

Methods

Forty-eight Sprague–Dawley rats were divided into two (Group A and B). Each group was further subdivided into three subgroups (AS, AC, AL, BS, BC, BL) containing eight rats. Appendectomy was performed and stump was closed by ligatures in S, by endoclips in C and by LigaSure™ in L subgroups. OT was recorded. In Group A, cecum bursting pressures (BP) were determined instantly after the operation. In Group B, BP, histological evaluations, and measurements of collagen contents estimated by the tissue hydroxyproline (HPL) level were made on the seventh postoperative day. Statistical analyses were performed with Kruskal–Wallis test and Mann–Whitney U test. P value was considered significant at less than 0.05.

Results

BPs of subgroups were comparable on postoperative immediate period and day 7. HPLs and OTs were significantly better in L subgroups. BL had the least inflammation.

Conclusion

Better healing, less inflammation, shorter OT, and equal strength achieved with LigaSure™ device comparing with polyglactin 910 ties and endoclips in experimental appendectomy is encouraging.

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Title: LigaSure™ compared with ligatures and endoclips in experimental appendectomy: how safe is it?
Authors: Levent Elemen
Yusufhan Yazir
Melih Tugay
Alper Akay
Seval Aydin
Karolin Yanar
Süreyya Ceylan
Publication date: 01-05-2010
Publisher: Springer-Verlag
Published in: Pediatric Surgery International / Issue 5/2010
Print ISSN: 0179-0358
Electronic ISSN: 1437-9813
DOI: https://doi.org/10.1007/s00383-010-2557-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

LigaSure™ compared with ligatures and endoclips in experimental appendectomy: how safe is it?

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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