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Published in: World Journal of Urology 3/2021

01-03-2021 | Prostate Cancer | Topic Paper

Advanced ultrasound in the diagnosis of prostate cancer

Authors: Jean-Michel Correas, Ethan J. Halpern, Richard G. Barr, Sangeet Ghai, Jochen Walz, Sylvain Bodard, Charles Dariane, Jean de la Rosette

Published in: World Journal of Urology | Issue 3/2021

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Abstract

The diagnosis of prostate cancer (PCa) can be challenging due to the limited performance of current diagnostic tests, including PSA, digital rectal examination and transrectal conventional US. Multiparametric MRI has improved PCa diagnosis and is recommended prior to biopsy; however, mp-MRI does miss a substantial number of PCa. Advanced US modalities include transrectal prostate elastography and contrast-enhanced US, as well as improved B-mode, micro-US and micro-Doppler techniques. These techniques can be combined to define a novel US approach, multiparametric US (mp-US). Mp-US improves PCa diagnosis but is not sufficiently accurate to obviate the utility of mp-MRI. Mp-US using advanced techniques and mp-MRI provide complementary information which will become even more important in the era of focal therapy, where precise identification of PCa location is needed.
Literature
35.
go back to reference Tuxhorn JA, Ayala GE, Rowley DR (2001) Reactive stroma in prostate cancer progression. J Urol 166:2472–2483CrossRef Tuxhorn JA, Ayala GE, Rowley DR (2001) Reactive stroma in prostate cancer progression. J Urol 166:2472–2483CrossRef
37.
go back to reference Tuxhorn JA, Ayala GE, Smith MJ et al (2002) Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res 8:2912–2923PubMed Tuxhorn JA, Ayala GE, Smith MJ et al (2002) Reactive stroma in human prostate cancer: induction of myofibroblast phenotype and extracellular matrix remodeling. Clin Cancer Res 8:2912–2923PubMed
54.
go back to reference Wang R, Chen J-J, Hu B (2015) Transrectal real-time elastography-guided transperineal prostate biopsy as an improved tool for prostate cancer diagnosis. Int J Clin Exp Med 8:6522–6529PubMedPubMedCentral Wang R, Chen J-J, Hu B (2015) Transrectal real-time elastography-guided transperineal prostate biopsy as an improved tool for prostate cancer diagnosis. Int J Clin Exp Med 8:6522–6529PubMedPubMedCentral
77.
go back to reference Apfelbeck M, Chaloupka M, Schlenker B et al (2019) Follow-up after focal therapy of the prostate with high intensity focused ultrasound (HIFU) using contrast enhanced ultrasound (CEUS) in combination with MRI image fusion. Clin Hemorheol Microcirc 73:135–143. https://doi.org/10.3233/CH-199222CrossRefPubMed Apfelbeck M, Chaloupka M, Schlenker B et al (2019) Follow-up after focal therapy of the prostate with high intensity focused ultrasound (HIFU) using contrast enhanced ultrasound (CEUS) in combination with MRI image fusion. Clin Hemorheol Microcirc 73:135–143. https://​doi.​org/​10.​3233/​CH-199222CrossRefPubMed
78.
go back to reference Moschouris H, Stamatiou K, Malagari K et al (2019) The value of contrast-enhanced ultrasonography in detection of prostatic infarction after prostatic artery embolization for the treatment of symptomatic benign prostatic hyperplasia. Diagn Interv Radiol Ank Turk 25:134–143. https://doi.org/10.5152/dir.2019.18410CrossRef Moschouris H, Stamatiou K, Malagari K et al (2019) The value of contrast-enhanced ultrasonography in detection of prostatic infarction after prostatic artery embolization for the treatment of symptomatic benign prostatic hyperplasia. Diagn Interv Radiol Ank Turk 25:134–143. https://​doi.​org/​10.​5152/​dir.​2019.​18410CrossRef
87.
go back to reference Zhang M, Tang J, Luo Y et al (2019) Diagnostic performance of multiparametric transrectal ultrasound in localized prostate cancer: a comparative study with magnetic resonance imaging. J Ultrasound Med Off J Am Inst Ultrasound Med 38:1823–1830. https://doi.org/10.1002/jum.14878CrossRef Zhang M, Tang J, Luo Y et al (2019) Diagnostic performance of multiparametric transrectal ultrasound in localized prostate cancer: a comparative study with magnetic resonance imaging. J Ultrasound Med Off J Am Inst Ultrasound Med 38:1823–1830. https://​doi.​org/​10.​1002/​jum.​14878CrossRef
Metadata
Title
Advanced ultrasound in the diagnosis of prostate cancer
Authors
Jean-Michel Correas
Ethan J. Halpern
Richard G. Barr
Sangeet Ghai
Jochen Walz
Sylvain Bodard
Charles Dariane
Jean de la Rosette
Publication date
01-03-2021
Publisher
Springer Berlin Heidelberg
Published in
World Journal of Urology / Issue 3/2021
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI
https://doi.org/10.1007/s00345-020-03193-0

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