Skip to main content
Top
Published in: European Radiology 5/2018

01-05-2018 | Musculoskeletal

Evaluation of vertebral body fractures using susceptibility-weighted magnetic resonance imaging

Authors: Sarah M. Böker, Lisa C. Adams, Yvonne Y. Bender, Moritz Wagner, Torsten Diekhoff, Eva Fallenberg, Bernd Hamm, Marcus R. Makowski

Published in: European Radiology | Issue 5/2018

Login to get access

Abstract

Purpose

To test the diagnostic performance of susceptibility-weighted MRI (sMRI) for the evaluation of vertebral body fractures versus standard MRI-sequences, using CT as reference standard.

Methods

In this prospective study 88 vertebral fractures (45 healed, 43 non-healed) were detected in 39 patients who underwent T1/T2/TIRM MRI-sequences and sMRI. All fractures were evaluated with CT as reference standard. In all modalities/sequences, displacement and height of the posterior vertebral body cortex and visibility of fracture lines and cortical breaks were assessed. Sensitivity, specificity and inter-reader agreement between MRI and CT were calculated.

Results

sMRI demonstrated highest diagnostic accuracy for detection of posterior vertebral body cortex involvement (sensitivity: 98 %/specificity: 100 %), fracture lines (86 %/99 %) and cortical breaks (93 %/100 %) versus T1/T2/TIRM sequences. Regarding evaluation of posterior vertebral body cortex displacement and height, sMRI demonstrated the closest intermodality agreement (R2=0.96; 95 % CI -0.92–0.89/R2=0.97; 95 % CI -1.67–1.23) with CT and the closest interobserver agreement (R2=0.97; 95 % CI -0.71–1.01).

Conclusion

sMRI allows reliable evaluation of vertebral body fractures with regard to posterior vertebral body cortex displacement and height, cortical breaks and fracture lines with higher accuracy versus standard MRI, especially in patients with non-healed vertebral body fractures.

Key Points

sMRI allows a reliable evaluation of vertebral body fractures.
sMRI has higher accuracy than standard-MRI for evaluation of vertebral body fractures.
sMRI is especially useful in patients with non-healed vertebral body fractures.
Literature
1.
go back to reference Waterloo S, Ahmed LA, Center JR et al (2012) Prevalence of vertebral fractures in women and men in the population-based Tromso Study. BMC Musculoskelet Disord 13:3CrossRefPubMedPubMedCentral Waterloo S, Ahmed LA, Center JR et al (2012) Prevalence of vertebral fractures in women and men in the population-based Tromso Study. BMC Musculoskelet Disord 13:3CrossRefPubMedPubMedCentral
2.
go back to reference Parizel PM, van der Zijden T, Gaudino S et al (2010) Trauma of the spine and spinal cord: imaging strategies. Eur Spine J 19:S8–17CrossRefPubMed Parizel PM, van der Zijden T, Gaudino S et al (2010) Trauma of the spine and spinal cord: imaging strategies. Eur Spine J 19:S8–17CrossRefPubMed
4.
go back to reference Kurz FT, Freitag M, Schlemmer HP, Bendszus M, Ziener CH (2016) Principles and applications of susceptibility weighted imaging. Radiologe 56:124–136CrossRefPubMed Kurz FT, Freitag M, Schlemmer HP, Bendszus M, Ziener CH (2016) Principles and applications of susceptibility weighted imaging. Radiologe 56:124–136CrossRefPubMed
5.
go back to reference Bai Y, Wang MY, Han YH et al (2013) Susceptibility weighted imaging: a new tool in the diagnosis of prostate cancer and detection of prostatic calcification. PLoS One 8:e53237CrossRefPubMedPubMedCentral Bai Y, Wang MY, Han YH et al (2013) Susceptibility weighted imaging: a new tool in the diagnosis of prostate cancer and detection of prostatic calcification. PLoS One 8:e53237CrossRefPubMedPubMedCentral
7.
go back to reference Cheng AL, Batool S, McCreary CR et al (2013) Susceptibility-weighted imaging is more reliable than T2*-weighted gradient-recalled echo MRI for detecting microbleeds. Stroke 44:2782–2786CrossRefPubMed Cheng AL, Batool S, McCreary CR et al (2013) Susceptibility-weighted imaging is more reliable than T2*-weighted gradient-recalled echo MRI for detecting microbleeds. Stroke 44:2782–2786CrossRefPubMed
8.
go back to reference Haacke EM, Mittal S, Wu Z, Neelavalli J, Cheng YC (2009) Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. AJNR Am J Neuroradiol 30:19–30CrossRefPubMed Haacke EM, Mittal S, Wu Z, Neelavalli J, Cheng YC (2009) Susceptibility-weighted imaging: technical aspects and clinical applications, part 1. AJNR Am J Neuroradiol 30:19–30CrossRefPubMed
9.
go back to reference Nih Consensus Development Panel on Osteoporosis Prevention D, Therapy (2001) Osteoporosis prevention, diagnosis, and therapy. JAMA 285:785–795CrossRef Nih Consensus Development Panel on Osteoporosis Prevention D, Therapy (2001) Osteoporosis prevention, diagnosis, and therapy. JAMA 285:785–795CrossRef
10.
go back to reference Denis F (1983) The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine (Phila Pa 1976) 8:817–831CrossRef Denis F (1983) The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine (Phila Pa 1976) 8:817–831CrossRef
11.
go back to reference Crim JR, Moore K, Brodke D (2001) Clearance of the cervical spine in multitrauma patients: the role of advanced imaging. Semin Ultrasound CT MR 22:283–305CrossRefPubMed Crim JR, Moore K, Brodke D (2001) Clearance of the cervical spine in multitrauma patients: the role of advanced imaging. Semin Ultrasound CT MR 22:283–305CrossRefPubMed
12.
go back to reference Platzer P, Jaindl M, Thalhammer G et al (2006) Clearing the cervical spine in critically injured patients: a comprehensive C-spine protocol to avoid unnecessary delays in diagnosis. Eur Spine J 15:1801–1810CrossRefPubMed Platzer P, Jaindl M, Thalhammer G et al (2006) Clearing the cervical spine in critically injured patients: a comprehensive C-spine protocol to avoid unnecessary delays in diagnosis. Eur Spine J 15:1801–1810CrossRefPubMed
13.
go back to reference Mittal S, Wu Z, Neelavalli J, Haacke EM (2009) Susceptibility-weighted imaging: technical aspects and clinical applications, part 2. AJNR Am J Neuroradiol 30:232–252CrossRefPubMedPubMedCentral Mittal S, Wu Z, Neelavalli J, Haacke EM (2009) Susceptibility-weighted imaging: technical aspects and clinical applications, part 2. AJNR Am J Neuroradiol 30:232–252CrossRefPubMedPubMedCentral
14.
go back to reference Haacke EM, Xu Y, Cheng YC, Reichenbach JR (2004) Susceptibility weighted imaging (SWI). Magn Reson Med 52:612–618CrossRefPubMed Haacke EM, Xu Y, Cheng YC, Reichenbach JR (2004) Susceptibility weighted imaging (SWI). Magn Reson Med 52:612–618CrossRefPubMed
15.
go back to reference Di Ieva A, Lam T, Alcaide-Leon P, Bharatha A, Montanera W, Cusimano MD (2015) Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives. J Neurosurg 123:1463–1475CrossRefPubMed Di Ieva A, Lam T, Alcaide-Leon P, Bharatha A, Montanera W, Cusimano MD (2015) Magnetic resonance susceptibility weighted imaging in neurosurgery: current applications and future perspectives. J Neurosurg 123:1463–1475CrossRefPubMed
16.
go back to reference Chen W, Zhu W, Kovanlikaya I et al (2014) Intracranial calcifications and hemorrhages: characterization with quantitative susceptibility mapping. Radiology 270:496–505CrossRefPubMedPubMedCentral Chen W, Zhu W, Kovanlikaya I et al (2014) Intracranial calcifications and hemorrhages: characterization with quantitative susceptibility mapping. Radiology 270:496–505CrossRefPubMedPubMedCentral
17.
go back to reference Tong KA, Ashwal S, Holshouser BA et al (2003) Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology 227:332–339CrossRefPubMed Tong KA, Ashwal S, Holshouser BA et al (2003) Hemorrhagic shearing lesions in children and adolescents with posttraumatic diffuse axonal injury: improved detection and initial results. Radiology 227:332–339CrossRefPubMed
18.
go back to reference Tong KA, Ashwal S, Obenaus A, Nickerson JP, Kido D, Haacke EM (2008) Susceptibility-weighted MR imaging: a review of clinical applications in children. AJNR Am J Neuroradiol 29:9–17CrossRefPubMed Tong KA, Ashwal S, Obenaus A, Nickerson JP, Kido D, Haacke EM (2008) Susceptibility-weighted MR imaging: a review of clinical applications in children. AJNR Am J Neuroradiol 29:9–17CrossRefPubMed
19.
go back to reference Nandigam RN, Viswanathan A, Delgado P et al (2009) MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength. AJNR Am J Neuroradiol 30:338–343CrossRefPubMed Nandigam RN, Viswanathan A, Delgado P et al (2009) MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength. AJNR Am J Neuroradiol 30:338–343CrossRefPubMed
20.
go back to reference Gao T, Wang Y, Zhang Z (2008) Silent cerebral microbleeds on susceptibility-weighted imaging of patients with ischemic stroke and leukoaraiosis. Neurol Res 30:272–276CrossRefPubMed Gao T, Wang Y, Zhang Z (2008) Silent cerebral microbleeds on susceptibility-weighted imaging of patients with ischemic stroke and leukoaraiosis. Neurol Res 30:272–276CrossRefPubMed
21.
go back to reference Santhosh K, Kesavadas C, Thomas B, Gupta AK, Thamburaj K, Kapilamoorthy TR (2009) Susceptibility weighted imaging: a new tool in magnetic resonance imaging of stroke. Clin Radiol 64:74–83CrossRefPubMed Santhosh K, Kesavadas C, Thomas B, Gupta AK, Thamburaj K, Kapilamoorthy TR (2009) Susceptibility weighted imaging: a new tool in magnetic resonance imaging of stroke. Clin Radiol 64:74–83CrossRefPubMed
22.
go back to reference Norenberg D, Ebersberger HU, Walter T et al (2016) Diagnosis of Calcific Tendonitis of the Rotator Cuff by Using Susceptibility-weighted MR Imaging. Radiology 278:475–484CrossRefPubMed Norenberg D, Ebersberger HU, Walter T et al (2016) Diagnosis of Calcific Tendonitis of the Rotator Cuff by Using Susceptibility-weighted MR Imaging. Radiology 278:475–484CrossRefPubMed
23.
24.
go back to reference Chang SX, Li GW, Chen Y et al (2013) Characterizing venous vasculatures of hepatocellular carcinoma using a multi-breath-hold two-dimensional susceptibility weighted imaging. PLoS One 8:e65895CrossRefPubMedPubMedCentral Chang SX, Li GW, Chen Y et al (2013) Characterizing venous vasculatures of hepatocellular carcinoma using a multi-breath-hold two-dimensional susceptibility weighted imaging. PLoS One 8:e65895CrossRefPubMedPubMedCentral
Metadata
Title
Evaluation of vertebral body fractures using susceptibility-weighted magnetic resonance imaging
Authors
Sarah M. Böker
Lisa C. Adams
Yvonne Y. Bender
Moritz Wagner
Torsten Diekhoff
Eva Fallenberg
Bernd Hamm
Marcus R. Makowski
Publication date
01-05-2018
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 5/2018
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-017-5195-z

Other articles of this Issue 5/2018

European Radiology 5/2018 Go to the issue