Skip to main content
Top
Published in: European Radiology 10/2016

01-10-2016 | Cardiac

Automated tube voltage selection for radiation dose and contrast medium reduction at coronary CT angiography using 3rd generation dual-source CT

Authors: Stefanie Mangold, Julian L. Wichmann, U. Joseph Schoepf, Zachary B. Poole, Christian Canstein, Akos Varga-Szemes, Damiano Caruso, Fabian Bamberg, Konstantin Nikolaou, Carlo N. De Cecco

Published in: European Radiology | Issue 10/2016

Login to get access

Abstract

Objectives

To investigate the relationship between automated tube voltage selection (ATVS) and body mass index (BMI) and its effect on image quality and radiation dose of coronary CT angiography (CCTA).

Methods

We evaluated 272 patients who underwent CCTA with 3rd generation dual-source CT (DSCT). Prospectively ECG-triggered spiral acquisition was performed with automated tube current selection and advanced iterative reconstruction. Tube voltages were selected by ATVS (70-120 kV). BMI, effective dose (ED), and vascular attenuation in the coronary arteries were recorded. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were calculated. Five-point scales were used for subjective image quality analysis.

Results

Image quality was rated good to excellent in 98.9 % of examinations without significant differences for proximal and distal attenuation (all p ≥ .0516), whereas image noise was rated significantly higher at 70 kV compared to ≥100 kV (all p < .0266). However, no significant differences were observed in SNR or CNR at 70–120 kV (all p ≥ .0829). Mean ED at 70-120 kV was 1.5 ± 1.2 mSv, 2.4 ± 1.5 mSv, 3.6 ± 2.7 mSv, 5.9 ± 4.0 mSv, 7.9 ± 4.2 mSv, and 10.7 ± 4.1 mSv, respectively (all p ≤ .0414). Correlation analysis showed a moderate association between tube voltage and BMI (r = .639).

Conclusion

ATVS allows individual tube voltage adaptation for CCTA performed with 3rd generation DSCT, resulting in significantly decreased radiation exposure while maintaining image quality.

Key Points

Automated tube voltage selection allows an individual tube voltage adaption in CCTA.
A tube voltage-based reduction of contrast medium volume is feasible.
Image quality was maintained while radiation exposure was significantly decreased.
A moderate association between tube voltage and body mass index was found.
Appendix
Available only for authorised users
Literature
1.
go back to reference Meyer M, Haubenreisser H, Schoepf UJ et al (2014) Closing in on the K edge: coronary CT angiography at 100, 80, and 70 kV-initial comparison of a second- versus a third-generation dual-source CT system. Radiology 273:373–382CrossRefPubMed Meyer M, Haubenreisser H, Schoepf UJ et al (2014) Closing in on the K edge: coronary CT angiography at 100, 80, and 70 kV-initial comparison of a second- versus a third-generation dual-source CT system. Radiology 273:373–382CrossRefPubMed
2.
go back to reference Zhang LJ, Zhao YE, Schoepf UJ et al (2015) Seventy-Peak Kilovoltage high-pitch thoracic aortic CT angiography without ECG gating: evaluation of image quality and radiation dose. Acad Radiol 22:890–897CrossRefPubMed Zhang LJ, Zhao YE, Schoepf UJ et al (2015) Seventy-Peak Kilovoltage high-pitch thoracic aortic CT angiography without ECG gating: evaluation of image quality and radiation dose. Acad Radiol 22:890–897CrossRefPubMed
3.
go back to reference Zhang LJ, Qi L, Wang J et al (2014) Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience. Eur Radiol 24:1537–1546CrossRefPubMed Zhang LJ, Qi L, Wang J et al (2014) Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience. Eur Radiol 24:1537–1546CrossRefPubMed
4.
go back to reference Lu GM, Luo S, Meinel FG et al (2014) High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume. Eur Radiol 24:3260–3268CrossRefPubMed Lu GM, Luo S, Meinel FG et al (2014) High-pitch computed tomography pulmonary angiography with iterative reconstruction at 80 kVp and 20 mL contrast agent volume. Eur Radiol 24:3260–3268CrossRefPubMed
5.
go back to reference Hell MM, Bittner D, Schuhbaeck A et al (2014) Prospectively ECG-triggered high-pitch coronary angiography with third-generation dual-source CT at 70 kVp tube voltage: feasibility, image quality, radiation dose, and effect of iterative reconstruction. J Cardiovasc Comput Tomogr 8:418–425CrossRefPubMed Hell MM, Bittner D, Schuhbaeck A et al (2014) Prospectively ECG-triggered high-pitch coronary angiography with third-generation dual-source CT at 70 kVp tube voltage: feasibility, image quality, radiation dose, and effect of iterative reconstruction. J Cardiovasc Comput Tomogr 8:418–425CrossRefPubMed
6.
go back to reference Hu L, Wang Y, Hou H, Wei F, Yang G, Chen Y (2014) Radiation dose and image quality with abdominal computed tomography with automated dose-optimized tube voltage selection. J Int Med Res 42:1011–1017CrossRefPubMed Hu L, Wang Y, Hou H, Wei F, Yang G, Chen Y (2014) Radiation dose and image quality with abdominal computed tomography with automated dose-optimized tube voltage selection. J Int Med Res 42:1011–1017CrossRefPubMed
7.
go back to reference Winklehner A, Gordic S, Lauk E et al (2015) Automated attenuation-based tube voltage selection for body CTA: performance evaluation of 192-slice dual-source CT. Eur Radiol 25:2346–2353CrossRefPubMed Winklehner A, Gordic S, Lauk E et al (2015) Automated attenuation-based tube voltage selection for body CTA: performance evaluation of 192-slice dual-source CT. Eur Radiol 25:2346–2353CrossRefPubMed
8.
go back to reference Winklehner A, Goetti R, Baumueller S et al (2011) Automated attenuation-based tube potential selection for thoracoabdominal computed tomography angiography: improved dose effectiveness. Invest Radiol 46:767–773CrossRefPubMed Winklehner A, Goetti R, Baumueller S et al (2011) Automated attenuation-based tube potential selection for thoracoabdominal computed tomography angiography: improved dose effectiveness. Invest Radiol 46:767–773CrossRefPubMed
9.
go back to reference Goetti R, Winklehner A, Gordic S et al (2012) Automated attenuation-based kilovoltage selection: preliminary observations in patients after endovascular aneurysm repair of the abdominal aorta. AJR Am J Roentgenol 199:W380–385CrossRefPubMed Goetti R, Winklehner A, Gordic S et al (2012) Automated attenuation-based kilovoltage selection: preliminary observations in patients after endovascular aneurysm repair of the abdominal aorta. AJR Am J Roentgenol 199:W380–385CrossRefPubMed
10.
go back to reference Siegel MJ, Ramirez-Giraldo JC, Hildebolt C, Bradley D, Schmidt B (2013) Automated low-kilovoltage selection in pediatric computed tomography angiography: phantom study evaluating effects on radiation dose and image quality. Invest Radiol 48:584–589CrossRefPubMed Siegel MJ, Ramirez-Giraldo JC, Hildebolt C, Bradley D, Schmidt B (2013) Automated low-kilovoltage selection in pediatric computed tomography angiography: phantom study evaluating effects on radiation dose and image quality. Invest Radiol 48:584–589CrossRefPubMed
11.
go back to reference Schwarz F, Grandl K, Arnoldi A et al (2013) Lowering radiation exposure in CT angiography using automated tube potential selection and optimized iodine delivery rate. AJR Am J Roentgenol 200:W628–634CrossRefPubMed Schwarz F, Grandl K, Arnoldi A et al (2013) Lowering radiation exposure in CT angiography using automated tube potential selection and optimized iodine delivery rate. AJR Am J Roentgenol 200:W628–634CrossRefPubMed
12.
go back to reference Layritz C, Muschiol G, Flohr T et al (2013) Automated attenuation-based selection of tube voltage and tube current for coronary CT angiography: reduction of radiation exposure versus a BMI-based strategy with an expert investigator. J Cardiovasc Comput Tomogr 7:303–310CrossRefPubMed Layritz C, Muschiol G, Flohr T et al (2013) Automated attenuation-based selection of tube voltage and tube current for coronary CT angiography: reduction of radiation exposure versus a BMI-based strategy with an expert investigator. J Cardiovasc Comput Tomogr 7:303–310CrossRefPubMed
13.
go back to reference Lurz M, Lell MM, Wuest W et al (2015) Automated tube voltage selection in thoracoabdominal computed tomography at high pitch using a third-generation dual-source scanner: image quality and radiation dose performance. Invest Radiol 50:352–360CrossRefPubMed Lurz M, Lell MM, Wuest W et al (2015) Automated tube voltage selection in thoracoabdominal computed tomography at high pitch using a third-generation dual-source scanner: image quality and radiation dose performance. Invest Radiol 50:352–360CrossRefPubMed
14.
go back to reference Krazinski AW, Meinel FG, Schoepf UJ et al (2014) Reduced radiation dose and improved image quality at cardiovascular CT angiography by automated attenuation-based tube voltage selection: intra-individual comparison. Eur Radiol 24:2677–2684CrossRefPubMed Krazinski AW, Meinel FG, Schoepf UJ et al (2014) Reduced radiation dose and improved image quality at cardiovascular CT angiography by automated attenuation-based tube voltage selection: intra-individual comparison. Eur Radiol 24:2677–2684CrossRefPubMed
15.
go back to reference Spearman JV, Schoepf UJ, Rottenkolber M et al (2015) Effect of automated attenuation-based tube voltage selection on radiation dose at CT: an observational study on a global scale. radiology Spearman JV, Schoepf UJ, Rottenkolber M et al (2015) Effect of automated attenuation-based tube voltage selection on radiation dose at CT: an observational study on a global scale. radiology
16.
go back to reference Meinel FG, Canstein C, Schoepf UJ et al (2014) Image quality and radiation dose of low tube voltage 3rd generation dual-source coronary CT angiography in obese patients: a phantom study. Eur Radiol 24:1643–1650CrossRefPubMed Meinel FG, Canstein C, Schoepf UJ et al (2014) Image quality and radiation dose of low tube voltage 3rd generation dual-source coronary CT angiography in obese patients: a phantom study. Eur Radiol 24:1643–1650CrossRefPubMed
17.
go back to reference Austen WG, Edwards JE, Frye RL et al (1975) A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51:5–40CrossRefPubMed Austen WG, Edwards JE, Frye RL et al (1975) A reporting system on patients evaluated for coronary artery disease. Report of the Ad Hoc Committee for Grading of Coronary Artery Disease, Council on Cardiovascular Surgery, American Heart Association. Circulation 51:5–40CrossRefPubMed
18.
go back to reference Szucs-Farkas Z, Strautz T, Patak MA, Kurmann L, Vock P, Schindera ST (2009) Is body weight the most appropriate criterion to select patients eligible for low-dose pulmonary CT angiography? Analysis of objective and subjective image quality at 80 kVp in 100 patients. Eur Radiol 19:1914–1922CrossRefPubMed Szucs-Farkas Z, Strautz T, Patak MA, Kurmann L, Vock P, Schindera ST (2009) Is body weight the most appropriate criterion to select patients eligible for low-dose pulmonary CT angiography? Analysis of objective and subjective image quality at 80 kVp in 100 patients. Eur Radiol 19:1914–1922CrossRefPubMed
19.
go back to reference Yuan R, Shuman WP, Earls JP et al (2012) Reduced iodine load at CT pulmonary angiography with dual-energy monochromatic imaging: comparison with standard CT pulmonary angiography--a prospective randomized trial. Radiology 262:290–297CrossRefPubMed Yuan R, Shuman WP, Earls JP et al (2012) Reduced iodine load at CT pulmonary angiography with dual-energy monochromatic imaging: comparison with standard CT pulmonary angiography--a prospective randomized trial. Radiology 262:290–297CrossRefPubMed
20.
go back to reference Christner JA, Braun NN, Jacobsen MC, Carter RE, Kofler JM, McCollough CH (2012) Size-specific dose estimates for adult patients at CT of the torso. Radiology 265:841–847CrossRefPubMed Christner JA, Braun NN, Jacobsen MC, Carter RE, Kofler JM, McCollough CH (2012) Size-specific dose estimates for adult patients at CT of the torso. Radiology 265:841–847CrossRefPubMed
21.
go back to reference Deak PD, Smal Y, Kalender WA (2010) Multisection CT protocols: sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology 257:158–166CrossRefPubMed Deak PD, Smal Y, Kalender WA (2010) Multisection CT protocols: sex- and age-specific conversion factors used to determine effective dose from dose-length product. Radiology 257:158–166CrossRefPubMed
22.
go back to reference Boone JM SK, Cody DD, McCollough CH, McNitt-Gray MF, Toth TL (2011) Size-specific Dose Estimates (SSDE) in Pediatric and Adult Body CT Examinations. Report of Am Assoc Phys Med AAPM Task Group 204 2011 College Park, Md: American Association of Physicists in Medicine Boone JM SK, Cody DD, McCollough CH, McNitt-Gray MF, Toth TL (2011) Size-specific Dose Estimates (SSDE) in Pediatric and Adult Body CT Examinations. Report of Am Assoc Phys Med AAPM Task Group 204 2011 College Park, Md: American Association of Physicists in Medicine
23.
go back to reference Geyer LL, Glenn GR, De Cecco CN et al (2015) CT evaluation of small-diameter coronary artery stents: effect of an integrated circuit detector with iterative reconstruction. Radiology 276:706–714CrossRefPubMed Geyer LL, Glenn GR, De Cecco CN et al (2015) CT evaluation of small-diameter coronary artery stents: effect of an integrated circuit detector with iterative reconstruction. Radiology 276:706–714CrossRefPubMed
24.
go back to reference Wang R, Schoepf UJ, Wu R et al (2012) Image quality and radiation dose of low dose coronary CT angiography in obese patients: sinogram affirmed iterative reconstruction versus filtered back projection. Eur J Radiol 81:3141–3145CrossRefPubMed Wang R, Schoepf UJ, Wu R et al (2012) Image quality and radiation dose of low dose coronary CT angiography in obese patients: sinogram affirmed iterative reconstruction versus filtered back projection. Eur J Radiol 81:3141–3145CrossRefPubMed
25.
go back to reference Wang R, Schoepf UJ, Wu R et al (2014) Diagnostic accuracy of coronary CT angiography: comparison of filtered back projection and iterative reconstruction with different strengths. J Comput Assist Tomogr 38:179–184CrossRefPubMed Wang R, Schoepf UJ, Wu R et al (2014) Diagnostic accuracy of coronary CT angiography: comparison of filtered back projection and iterative reconstruction with different strengths. J Comput Assist Tomogr 38:179–184CrossRefPubMed
26.
go back to reference Moscariello A, Takx RA, Schoepf UJ et al (2011) Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique-comparison with traditional filtered back projection. Eur Radiol 21:2130–2138CrossRefPubMed Moscariello A, Takx RA, Schoepf UJ et al (2011) Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique-comparison with traditional filtered back projection. Eur Radiol 21:2130–2138CrossRefPubMed
27.
go back to reference Gordic S, Desbiolles L, Stolzmann P et al (2014) Advanced modelled iterative reconstruction for abdominal CT: qualitative and quantitative evaluation. Clin Radiol 69:e497–504CrossRefPubMed Gordic S, Desbiolles L, Stolzmann P et al (2014) Advanced modelled iterative reconstruction for abdominal CT: qualitative and quantitative evaluation. Clin Radiol 69:e497–504CrossRefPubMed
28.
go back to reference Moore BM, Brady SL, Mirro AE, Kaufman RA (2014) Size-specific dose estimate (SSDE) provides a simple method to calculate organ dose for pediatric CT examinations. Med Phys 41:071917CrossRefPubMed Moore BM, Brady SL, Mirro AE, Kaufman RA (2014) Size-specific dose estimate (SSDE) provides a simple method to calculate organ dose for pediatric CT examinations. Med Phys 41:071917CrossRefPubMed
29.
go back to reference Leschka S, Stinn B, Schmid F et al (2009) Dual source CT coronary angiography in severely obese patients: trading off temporal resolution and image noise. Invest Radiol 44:720–727CrossRefPubMed Leschka S, Stinn B, Schmid F et al (2009) Dual source CT coronary angiography in severely obese patients: trading off temporal resolution and image noise. Invest Radiol 44:720–727CrossRefPubMed
30.
go back to reference Lee AM, Engel LC, Hui GC et al (2014) Coronary computed tomography angiography at 140 kV versus 120 kV: assessment of image quality and radiation exposure in overweight and moderately obese patients. Acta Radiol 55:554–562CrossRefPubMed Lee AM, Engel LC, Hui GC et al (2014) Coronary computed tomography angiography at 140 kV versus 120 kV: assessment of image quality and radiation exposure in overweight and moderately obese patients. Acta Radiol 55:554–562CrossRefPubMed
Metadata
Title
Automated tube voltage selection for radiation dose and contrast medium reduction at coronary CT angiography using 3rd generation dual-source CT
Authors
Stefanie Mangold
Julian L. Wichmann
U. Joseph Schoepf
Zachary B. Poole
Christian Canstein
Akos Varga-Szemes
Damiano Caruso
Fabian Bamberg
Konstantin Nikolaou
Carlo N. De Cecco
Publication date
01-10-2016
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 10/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-015-4191-4

Other articles of this Issue 10/2016

European Radiology 10/2016 Go to the issue